FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2129134470> ?p ?o ?g. }

• W2129134470 endingPage "7008" @default.
• W2129134470 startingPage "7002" @default.
• W2129134470 abstract "The free-energy profile and the classical kinetics of the heme carbomonoxide binding-unbinding reaction have been derived by means of a theoretical method for the separated chains of human (HbA) and Trematomus newnesi major component (HbTn) hemoglobin. The results reveal that the alpha- and beta-chains of HbA have similar values of kinetic constants for the dissociation of the Fe-CO state, in agreement with experimental data. Comparisons of the present findings with the data obtained for the alpha- and beta-chains of HbTn and with theoretical and experimental results previously collected on myoglobin provide a detailed picture of this important biochemical reaction in globins. The sequence and structural differences among the globins are not reflected in meaningful variations in the rate of CO dissociation. These data support the conclusion that the differences observed for the reaction with CO of globins, if any, involve the rate of ligand migration to the solvent, rather than the Fe-CO complex formation/rupture. Furthermore, our results agree with the recent discovery that globin family proteins exhibit common dynamics, thus confirming the observation that the dynamic properties of proteins are strongly related to their overall architecture." @default.
• W2129134470 created "2016-06-24" @default.
• W2129134470 creator A5035401744 @default.
• W2129134470 creator A5051763103 @default.
• W2129134470 creator A5055343051 @default.
• W2129134470 creator A5060901464 @default.
• W2129134470 creator A5068959451 @default.
• W2129134470 creator A5069017579 @default.
• W2129134470 creator A5090817979 @default.
• W2129134470 date "2010-04-30" @default.
• W2129134470 modified "2023-09-26" @default.
• W2129134470 title "Free-Energy Profile for CO Binding to Separated Chains of Human and <i>Trematomus newnesi</i> Hemoglobin: Insights from Molecular Dynamics Simulations and Perturbed Matrix Method" @default.
• W2129134470 cites W1500934039 @default.
• W2129134470 cites W1548036462 @default.
• W2129134470 cites W1554537480 @default.
• W2129134470 cites W1554994168 @default.
• W2129134470 cites W1555755177 @default.
• W2129134470 cites W1560808158 @default.
• W2129134470 cites W1564662973 @default.
• W2129134470 cites W1565582771 @default.
• W2129134470 cites W1570157435 @default.
• W2129134470 cites W1596086690 @default.
• W2129134470 cites W1600719193 @default.
• W2129134470 cites W1965875500 @default.
• W2129134470 cites W1968632708 @default.
• W2129134470 cites W1976195668 @default.
• W2129134470 cites W1976898303 @default.
• W2129134470 cites W1981324267 @default.
• W2129134470 cites W1988159625 @default.
• W2129134470 cites W1993106535 @default.
• W2129134470 cites W2000756554 @default.
• W2129134470 cites W2004828021 @default.
• W2129134470 cites W2007413542 @default.
• W2129134470 cites W2012977027 @default.
• W2129134470 cites W2022950330 @default.
• W2129134470 cites W2023271753 @default.
• W2129134470 cites W2026911129 @default.
• W2129134470 cites W2035266068 @default.
• W2129134470 cites W2038870920 @default.
• W2129134470 cites W2041496578 @default.
• W2129134470 cites W2043263252 @default.
• W2129134470 cites W2046078166 @default.
• W2129134470 cites W2049233747 @default.
• W2129134470 cites W2053384651 @default.
• W2129134470 cites W2053879435 @default.
• W2129134470 cites W2055486927 @default.
• W2129134470 cites W2058269721 @default.
• W2129134470 cites W2063069917 @default.
• W2129134470 cites W2066860243 @default.
• W2129134470 cites W2067174909 @default.
• W2129134470 cites W2068617439 @default.
• W2129134470 cites W2075347439 @default.
• W2129134470 cites W2079109460 @default.
• W2129134470 cites W2085465175 @default.
• W2129134470 cites W2086041288 @default.
• W2129134470 cites W2087005294 @default.
• W2129134470 cites W2087217651 @default.
• W2129134470 cites W2115940223 @default.
• W2129134470 cites W2117510107 @default.
• W2129134470 cites W2141519313 @default.
• W2129134470 cites W2151616151 @default.
• W2129134470 cites W2155365495 @default.
• W2129134470 cites W2157765728 @default.
• W2129134470 cites W2158374287 @default.
• W2129134470 cites W2158785350 @default.
• W2129134470 cites W2165422947 @default.
• W2129134470 cites W2171268876 @default.
• W2129134470 cites W303512692 @default.
• W2129134470 doi "https://doi.org/10.1021/jp908525s" @default.
• W2129134470 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20433181" @default.
• W2129134470 hasPublicationYear "2010" @default.
• W2129134470 type Work @default.
• W2129134470 sameAs 2129134470 @default.
• W2129134470 citedByCount "7" @default.
• W2129134470 countsByYear W21291344702012 @default.
• W2129134470 countsByYear W21291344702013 @default.
• W2129134470 countsByYear W21291344702015 @default.
• W2129134470 countsByYear W21291344702021 @default.
• W2129134470 countsByYear W21291344702022 @default.
• W2129134470 crossrefType "journal-article" @default.
• W2129134470 hasAuthorship W2129134470A5035401744 @default.
• W2129134470 hasAuthorship W2129134470A5051763103 @default.
• W2129134470 hasAuthorship W2129134470A5055343051 @default.
• W2129134470 hasAuthorship W2129134470A5060901464 @default.
• W2129134470 hasAuthorship W2129134470A5068959451 @default.
• W2129134470 hasAuthorship W2129134470A5069017579 @default.
• W2129134470 hasAuthorship W2129134470A5090817979 @default.
• W2129134470 hasConcept C102931765 @default.
• W2129134470 hasConcept C121332964 @default.
• W2129134470 hasConcept C125996951 @default.
• W2129134470 hasConcept C135889238 @default.
• W2129134470 hasConcept C147597530 @default.
• W2129134470 hasConcept C147789679 @default.
• W2129134470 hasConcept C148898269 @default.
• W2129134470 hasConcept C181199279 @default.
• W2129134470 hasConcept C185592680 @default.
• W2129134470 hasConcept C20705724 @default.
• W2129134470 hasConcept C2776217839 @default.

• next