Matches in SemOpenAlex for { <https://semopenalex.org/work/W2129160980> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2129160980 endingPage "1658" @default.
- W2129160980 startingPage "1649" @default.
- W2129160980 abstract "Introduction: Carcinoid tumors are uncommon neoplasms that offer unique therapeutic challenges to practicing physicians. Several chemotherapy combinations and IFN-α have been used for the treatment of unresectable carcinoid tumors over the last decades, but they have shown variable clinical results. Given the heterogeneity of these tumors, there is no clear therapeutic agent or combination that confers a significant advantage over others. Areas covered: The authors provide a comprehensive evaluation of the existing therapies for advanced carcinoid tumors such as traditional agents, combination therapies and newer drugs. Expert opinion: Somatostatin analogs are known to provide symptomatic relief in patients with carcinoid syndrome, but their antiproliferative effect has not been proven beyond the reasonable doubt. Traditional streptozocin-based regimens may offer a survival benefit in patients with advanced carcinoids, yet their toxicity is not negligible. Temozolomide has shown efficacy alone and in combination with other agents, and its further testing in advanced carcinoid tumors appears warranted. Efficacy of various tyrosine kinase inhibitors, VEGF inhibitors and mTOR inhibitors appears promising, and should be explored in patients with metastatic carcinoid tumors. In addition, use of these agents in combination with traditional chemotherapeutic agents should also be investigated." @default.
- W2129160980 created "2016-06-24" @default.
- W2129160980 creator A5001190634 @default.
- W2129160980 creator A5006357848 @default.
- W2129160980 date "2013-06-08" @default.
- W2129160980 modified "2023-09-26" @default.
- W2129160980 title "Management of advanced and/or metastatic carcinoid tumors: historical perspectives and emerging therapies" @default.
- W2129160980 cites W1934218182 @default.
- W2129160980 cites W1964709676 @default.
- W2129160980 cites W1972776708 @default.
- W2129160980 cites W1975686877 @default.
- W2129160980 cites W1981791928 @default.
- W2129160980 cites W1993653750 @default.
- W2129160980 cites W2005782011 @default.
- W2129160980 cites W2016826196 @default.
- W2129160980 cites W2027212248 @default.
- W2129160980 cites W2039261671 @default.
- W2129160980 cites W2046130951 @default.
- W2129160980 cites W2057866936 @default.
- W2129160980 cites W205878571 @default.
- W2129160980 cites W2060370107 @default.
- W2129160980 cites W2061116727 @default.
- W2129160980 cites W2070739652 @default.
- W2129160980 cites W2071250852 @default.
- W2129160980 cites W2090232354 @default.
- W2129160980 cites W2098482546 @default.
- W2129160980 cites W2099933501 @default.
- W2129160980 cites W2100030097 @default.
- W2129160980 cites W2101632061 @default.
- W2129160980 cites W2102012621 @default.
- W2129160980 cites W2103931078 @default.
- W2129160980 cites W2107276199 @default.
- W2129160980 cites W2112064092 @default.
- W2129160980 cites W2114789973 @default.
- W2129160980 cites W2115686439 @default.
- W2129160980 cites W2118672029 @default.
- W2129160980 cites W2128112055 @default.
- W2129160980 cites W2128879260 @default.
- W2129160980 cites W2131492952 @default.
- W2129160980 cites W2131538638 @default.
- W2129160980 cites W2133106090 @default.
- W2129160980 cites W2133933220 @default.
- W2129160980 cites W2135657152 @default.
- W2129160980 cites W2135659425 @default.
- W2129160980 cites W2137142564 @default.
- W2129160980 cites W2148933046 @default.
- W2129160980 cites W2154819798 @default.
- W2129160980 cites W2161837928 @default.
- W2129160980 cites W2166100060 @default.
- W2129160980 cites W2261012745 @default.
- W2129160980 doi "https://doi.org/10.1517/14656566.2013.808623" @default.
- W2129160980 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23746075" @default.
- W2129160980 hasPublicationYear "2013" @default.
- W2129160980 type Work @default.
- W2129160980 sameAs 2129160980 @default.
- W2129160980 citedByCount "4" @default.
- W2129160980 countsByYear W21291609802016 @default.
- W2129160980 countsByYear W21291609802018 @default.
- W2129160980 countsByYear W21291609802019 @default.
- W2129160980 countsByYear W21291609802021 @default.
- W2129160980 crossrefType "journal-article" @default.
- W2129160980 hasAuthorship W2129160980A5001190634 @default.
- W2129160980 hasAuthorship W2129160980A5006357848 @default.
- W2129160980 hasConcept C126322002 @default.
- W2129160980 hasConcept C143998085 @default.
- W2129160980 hasConcept C177713679 @default.
- W2129160980 hasConcept C2776297358 @default.
- W2129160980 hasConcept C2776694085 @default.
- W2129160980 hasConcept C2777389519 @default.
- W2129160980 hasConcept C2778506435 @default.
- W2129160980 hasConcept C2779066768 @default.
- W2129160980 hasConcept C2781025020 @default.
- W2129160980 hasConcept C2781151469 @default.
- W2129160980 hasConcept C3020580240 @default.
- W2129160980 hasConcept C71924100 @default.
- W2129160980 hasConceptScore W2129160980C126322002 @default.
- W2129160980 hasConceptScore W2129160980C143998085 @default.
- W2129160980 hasConceptScore W2129160980C177713679 @default.
- W2129160980 hasConceptScore W2129160980C2776297358 @default.
- W2129160980 hasConceptScore W2129160980C2776694085 @default.
- W2129160980 hasConceptScore W2129160980C2777389519 @default.
- W2129160980 hasConceptScore W2129160980C2778506435 @default.
- W2129160980 hasConceptScore W2129160980C2779066768 @default.
- W2129160980 hasConceptScore W2129160980C2781025020 @default.
- W2129160980 hasConceptScore W2129160980C2781151469 @default.
- W2129160980 hasConceptScore W2129160980C3020580240 @default.
- W2129160980 hasConceptScore W2129160980C71924100 @default.
- W2129160980 hasIssue "12" @default.
- W2129160980 hasLocation W21291609801 @default.
- W2129160980 hasLocation W21291609802 @default.
- W2129160980 hasOpenAccess W2129160980 @default.
- W2129160980 hasPrimaryLocation W21291609801 @default.
- W2129160980 hasVolume "14" @default.
- W2129160980 isParatext "false" @default.
- W2129160980 isRetracted "false" @default.
- W2129160980 magId "2129160980" @default.
- W2129160980 workType "article" @default.