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• W2129207434 abstract "Brain white matter myelin abnormalities and cell membrane fatty acid abnormalities have been implicated in schizophrenia and other psychiatric disorders. We investigated in young adults with a psychotic disorder (n=12) whether (poly)unsaturated fatty acid concentrations in erythrocyte membranes are related to an MRI measure of brain white matter, which depends on the degree of myelination. A significant correlation was found between total (poly)unsaturated fatty acid concentration and fractional anisotropy of a fronto-temporal white matter tract (r=0.503, P=0.048). Unsaturated fatty acids may be necessary for the myelinating activity of oligodendrocytes or for myelin maintenance. These results warrant further investigation." @default.
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• W2129207434 date "2009-07-01" @default.
• W2129207434 modified "2023-10-01" @default.
• W2129207434 title "Polyunsaturated fatty acids and brain white matter anisotropy in recent-onset schizophrenia: A preliminary study" @default.
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• W2129207434 doi "https://doi.org/10.1016/j.plefa.2009.04.007" @default.
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• W2129207434 hasPublicationYear "2009" @default.
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