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• W2129302316 abstract "t l t m It is hard to believe today that the concept of reentrant xcitation as an important cause of cardiac arrhythmias as questioned in my professional lifetime. However, nce the occurrence of reentry was proven, first in animal odels of arrhythmias and later in patients, it led to the evelopment of interventional electrophysiology with a oal of being able to destroy (ablate) a crucial part of the eentrant circuit, thereby preventing the reentrant arhythmia. This idea stemmed from what Waldo (Personal ommunication) called the “Mines’ test” in our discusions about reentry. In his classic paper on circus moveent in the early 20th century, Gregory Mines showed hat cutting through the loop that formed the reentrant athway in a simple in vitro model stopped reentry. The ines’ test was first used successfully to prevent arrhythias associated with bypass tracts, which seemed like an mazing accomplishment at the time. Since then, the rocedure of ablation has proved very effective for some upraventricular arrhythmias, such as AV nodal reentrant achycardia and some types of atrial flutter. The success f ablation in these circumstances is due to the predictble location of the reentrant circuits that are targeted for estruction. Unfortunately, ablation of ventricular tachyardia (VT) associated with healed myocardial infarction as been less successful because locating the reentrant ircuit is problematic and procedures for doing so are xtremely time consuming. Current approaches include nduction of the tachycardia with programmed stimulaion, mapping activation with multiple roving catheters, nd entrainment from multiple sites. Because tachycarias must be sustained and hemodynamically tolerated in rder for these techniques to be applied, only some tachyardias are amenable to this approach. To add to the omplexity, patients can have tachycardias with multiple orphologies, suggesting the possibility that different achycardias arise from different reentrant circuits and" @default.
• W2129302316 created "2016-06-24" @default.
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• W2129302316 date "2006-02-01" @default.
• W2129302316 modified "2023-10-14" @default.
• W2129302316 title "Ablation of ventricular tachycardia: Does anyone have any new ideas?" @default.
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• W2129302316 doi "https://doi.org/10.1016/j.hrthm.2005.12.007" @default.
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