Matches in SemOpenAlex for { <https://semopenalex.org/work/W2129311531> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2129311531 endingPage "11" @default.
- W2129311531 startingPage "1" @default.
- W2129311531 abstract "Diabetes mellitus (DM) affects all the process of spermatogenesis. Chronic hyperglycemia in DM increases the expression of receptor for advanced glycosilation end products (RAGE) that is responsible for the activation of signal production of reactive oxygen species (ROS) and caspase 3. Active caspase 3 plays an important role in cell apoptosis. Soybean ( G lycin max ) is reported to have antihyperglycemic and antiadvanced glycosilation end products (antiAGE) and antioxidants activities. The aim of this study was to evaluate the effect of soybean powder suspension on the expression of RAGE and active caspase 3 of diabetic rats’ sperm. This was an experimental study with post test only control group design using 30 male Sprague Dawley rats, aged 11-12 weeks old and weighed 200-250g. The rats were divided into five groups with six rats in each group. Group 1 was non diabetic rats and Group 2 was diabetic rats that were given aquadest. Group 3-5 were diabetic rats that were given a soybean powder suspension at dose of 400; 800 and 1600 mg/kg body weight (BW)/day, respectively. Diabetic rats were made by induction of a single intraperitoneal injection of streptozotocin (STZ) at a dose of 60 mg/kg BW. Soybean powder suspension was ingested for four weeks after 14 days STZ induction. Blood glucose levels were monitored before and three days after STZ induction and four weeks after suspension ingestion. The expression of RAGE and active caspase-3 were analyzed using immunohistochemistry method four weeks after suspension ingestion. The results showed that soybean powder suspension ingestion significantly decreased blood glucose level of diabetic rats toward normality (p<0.05). However, the expression of RAGE and active caspase-3 in diabetic rats’ sperm were not significantly lower than those after suspension ingestion. In conclusion, soybean powder suspension does not significantly affect the expression of RAGE and active caspase-3 in diabetic rats’ sperm." @default.
- W2129311531 created "2016-06-24" @default.
- W2129311531 creator A5023903450 @default.
- W2129311531 creator A5047310218 @default.
- W2129311531 creator A5065043388 @default.
- W2129311531 date "2013-03-01" @default.
- W2129311531 modified "2023-10-03" @default.
- W2129311531 title "Expression of receptor advanced glycosilation end product (RAGE) and active caspase-3 of the streptozotocin-induced chronic diabetes mellitus Sprague Dawley rats’ sperm with soybean (Glycin max) powder suspension treatment" @default.
- W2129311531 doi "https://doi.org/10.19106/jmedscie004501201301" @default.
- W2129311531 hasPublicationYear "2013" @default.
- W2129311531 type Work @default.
- W2129311531 sameAs 2129311531 @default.
- W2129311531 citedByCount "0" @default.
- W2129311531 crossrefType "journal-article" @default.
- W2129311531 hasAuthorship W2129311531A5023903450 @default.
- W2129311531 hasAuthorship W2129311531A5047310218 @default.
- W2129311531 hasAuthorship W2129311531A5065043388 @default.
- W2129311531 hasBestOaLocation W21293115311 @default.
- W2129311531 hasConcept C126322002 @default.
- W2129311531 hasConcept C134018914 @default.
- W2129311531 hasConcept C16685009 @default.
- W2129311531 hasConcept C169760540 @default.
- W2129311531 hasConcept C185592680 @default.
- W2129311531 hasConcept C190283241 @default.
- W2129311531 hasConcept C2778857457 @default.
- W2129311531 hasConcept C2779280383 @default.
- W2129311531 hasConcept C2780159080 @default.
- W2129311531 hasConcept C2781087480 @default.
- W2129311531 hasConcept C55493867 @default.
- W2129311531 hasConcept C555293320 @default.
- W2129311531 hasConcept C71924100 @default.
- W2129311531 hasConcept C86803240 @default.
- W2129311531 hasConceptScore W2129311531C126322002 @default.
- W2129311531 hasConceptScore W2129311531C134018914 @default.
- W2129311531 hasConceptScore W2129311531C16685009 @default.
- W2129311531 hasConceptScore W2129311531C169760540 @default.
- W2129311531 hasConceptScore W2129311531C185592680 @default.
- W2129311531 hasConceptScore W2129311531C190283241 @default.
- W2129311531 hasConceptScore W2129311531C2778857457 @default.
- W2129311531 hasConceptScore W2129311531C2779280383 @default.
- W2129311531 hasConceptScore W2129311531C2780159080 @default.
- W2129311531 hasConceptScore W2129311531C2781087480 @default.
- W2129311531 hasConceptScore W2129311531C55493867 @default.
- W2129311531 hasConceptScore W2129311531C555293320 @default.
- W2129311531 hasConceptScore W2129311531C71924100 @default.
- W2129311531 hasConceptScore W2129311531C86803240 @default.
- W2129311531 hasIssue "01" @default.
- W2129311531 hasLocation W21293115311 @default.
- W2129311531 hasLocation W21293115312 @default.
- W2129311531 hasOpenAccess W2129311531 @default.
- W2129311531 hasPrimaryLocation W21293115311 @default.
- W2129311531 hasRelatedWork W1966333843 @default.
- W2129311531 hasRelatedWork W1970147106 @default.
- W2129311531 hasRelatedWork W1987421851 @default.
- W2129311531 hasRelatedWork W2068155960 @default.
- W2129311531 hasRelatedWork W2380317211 @default.
- W2129311531 hasRelatedWork W2400445066 @default.
- W2129311531 hasRelatedWork W254875709 @default.
- W2129311531 hasRelatedWork W2588257954 @default.
- W2129311531 hasRelatedWork W2754118680 @default.
- W2129311531 hasRelatedWork W3209025627 @default.
- W2129311531 hasVolume "45" @default.
- W2129311531 isParatext "false" @default.
- W2129311531 isRetracted "false" @default.
- W2129311531 magId "2129311531" @default.
- W2129311531 workType "article" @default.