Matches in SemOpenAlex for { <https://semopenalex.org/work/W2129327996> ?p ?o ?g. }
- W2129327996 endingPage "944" @default.
- W2129327996 startingPage "939" @default.
- W2129327996 abstract "Background/Aims: Forty-two patients with the diagnosis of acute hepatitis C virus hepatitis were studied to investigate the relationship between hepatitis C virus genotype and progression to chronic infection. Methods: The patients were followed for more than 1 year (mean age 29 years, male/female ratio 2.5). Intravenous drug use was documented in 15 cases, blood transfusion in four, surgical intervention, dental therapy or other parenteral exposure in 15, and unknown factors in the remaining eight. The evolution to chronicity was diagnosed on the basis of a persistent increase in transaminase levels, the presence of HCV RNA and the histological pattern of chronic hepatitis. Results:The majority of cases presented hepatitis C virus infection of substype 1a (38.1%) or 1b (33.9%). Six cases showed the presence of genotype 3a (14.3%). Subtype 2c was observed in three out of four cases infected with genotype 2. No significant association was demonstrated with documented risk factors. The overall chronicity rate was 59.5%. This value increased to 92% in individuals infected with genotype 1b. By multivariate analysis the age-adjusted odds ratio for infection with genotype 1b as compared with all other genotypes was 14.4 (95% confidence interval; 1.52–137). Moreover, significant differences (p=0.0002) were present in this group for histological activity index (8.7 as compared with 5–7). Conclusions: The results of this prospective study are consistent with an independent association between hepatitis C virus genotype 1b and a poor prognosis." @default.
- W2129327996 created "2016-06-24" @default.
- W2129327996 creator A5019688645 @default.
- W2129327996 creator A5020059497 @default.
- W2129327996 creator A5023823071 @default.
- W2129327996 creator A5030772725 @default.
- W2129327996 creator A5031621445 @default.
- W2129327996 creator A5045472214 @default.
- W2129327996 creator A5051515112 @default.
- W2129327996 creator A5052156980 @default.
- W2129327996 creator A5054908504 @default.
- W2129327996 creator A5066899550 @default.
- W2129327996 creator A5084550895 @default.
- W2129327996 date "1998-06-01" @default.
- W2129327996 modified "2023-09-26" @default.
- W2129327996 title "Correlation between virus genotype and chronicity rate in acute hepatitis C" @default.
- W2129327996 cites W1975188685 @default.
- W2129327996 cites W1981812015 @default.
- W2129327996 cites W1997368021 @default.
- W2129327996 cites W2001241073 @default.
- W2129327996 cites W2004350674 @default.
- W2129327996 cites W2006309458 @default.
- W2129327996 cites W2022263369 @default.
- W2129327996 cites W2033199408 @default.
- W2129327996 cites W2057381677 @default.
- W2129327996 cites W2067186215 @default.
- W2129327996 cites W2073585022 @default.
- W2129327996 cites W2085600385 @default.
- W2129327996 cites W2090162548 @default.
- W2129327996 cites W2099536639 @default.
- W2129327996 cites W2108222646 @default.
- W2129327996 cites W2109048688 @default.
- W2129327996 cites W2110309669 @default.
- W2129327996 cites W2111424027 @default.
- W2129327996 cites W2115956200 @default.
- W2129327996 cites W2122216714 @default.
- W2129327996 cites W2127869931 @default.
- W2129327996 cites W2132290252 @default.
- W2129327996 cites W2143174310 @default.
- W2129327996 cites W2149685209 @default.
- W2129327996 cites W2163692778 @default.
- W2129327996 cites W2165837787 @default.
- W2129327996 cites W2205037079 @default.
- W2129327996 cites W2313300349 @default.
- W2129327996 cites W2328171401 @default.
- W2129327996 cites W3186377935 @default.
- W2129327996 cites W4232088988 @default.
- W2129327996 doi "https://doi.org/10.1016/s0168-8278(98)80340-1" @default.
- W2129327996 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9672167" @default.
- W2129327996 hasPublicationYear "1998" @default.
- W2129327996 type Work @default.
- W2129327996 sameAs 2129327996 @default.
- W2129327996 citedByCount "112" @default.
- W2129327996 countsByYear W21293279962012 @default.
- W2129327996 countsByYear W21293279962013 @default.
- W2129327996 countsByYear W21293279962014 @default.
- W2129327996 countsByYear W21293279962015 @default.
- W2129327996 countsByYear W21293279962016 @default.
- W2129327996 countsByYear W21293279962017 @default.
- W2129327996 countsByYear W21293279962018 @default.
- W2129327996 countsByYear W21293279962019 @default.
- W2129327996 countsByYear W21293279962021 @default.
- W2129327996 countsByYear W21293279962022 @default.
- W2129327996 countsByYear W21293279962023 @default.
- W2129327996 crossrefType "journal-article" @default.
- W2129327996 hasAuthorship W2129327996A5019688645 @default.
- W2129327996 hasAuthorship W2129327996A5020059497 @default.
- W2129327996 hasAuthorship W2129327996A5023823071 @default.
- W2129327996 hasAuthorship W2129327996A5030772725 @default.
- W2129327996 hasAuthorship W2129327996A5031621445 @default.
- W2129327996 hasAuthorship W2129327996A5045472214 @default.
- W2129327996 hasAuthorship W2129327996A5051515112 @default.
- W2129327996 hasAuthorship W2129327996A5052156980 @default.
- W2129327996 hasAuthorship W2129327996A5054908504 @default.
- W2129327996 hasAuthorship W2129327996A5066899550 @default.
- W2129327996 hasAuthorship W2129327996A5084550895 @default.
- W2129327996 hasConcept C104317684 @default.
- W2129327996 hasConcept C126322002 @default.
- W2129327996 hasConcept C135763542 @default.
- W2129327996 hasConcept C156957248 @default.
- W2129327996 hasConcept C203014093 @default.
- W2129327996 hasConcept C2522874641 @default.
- W2129327996 hasConcept C2776029263 @default.
- W2129327996 hasConcept C2776408679 @default.
- W2129327996 hasConcept C2778606649 @default.
- W2129327996 hasConcept C2780567839 @default.
- W2129327996 hasConcept C44249647 @default.
- W2129327996 hasConcept C55493867 @default.
- W2129327996 hasConcept C71924100 @default.
- W2129327996 hasConcept C86803240 @default.
- W2129327996 hasConcept C90924648 @default.
- W2129327996 hasConceptScore W2129327996C104317684 @default.
- W2129327996 hasConceptScore W2129327996C126322002 @default.
- W2129327996 hasConceptScore W2129327996C135763542 @default.
- W2129327996 hasConceptScore W2129327996C156957248 @default.
- W2129327996 hasConceptScore W2129327996C203014093 @default.
- W2129327996 hasConceptScore W2129327996C2522874641 @default.
- W2129327996 hasConceptScore W2129327996C2776029263 @default.