FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2129343311> ?p ?o ?g. }

• W2129343311 endingPage "A1320" @default.
• W2129343311 startingPage "A1320" @default.
• W2129343311 abstract "Following orthotopic liver transplantation (OLT) histological examination of explant livers from patients with alcoholic liver disease (ALD) sometimes shows extensive iron deposits in a distribution suggestive of homozygous haemochromatosis.To use haemochromatosis gene (HFE) assays to distinguish between ALD with notable siderosis and hereditary haemochromatosis. To evaluate the possible influence of spur cell haemolytic anaemia on hepatic iron loading.Thirty seven patients with ALD were abstinent for at least six months prior to OLT. Twenty three patients had transferrin saturations greater than 55%, 16 also had increased serum ferritin (>350 micrograms/l). Eight of 37 (22%) explant livers had grade 3 or 4 hepatic iron deposition, predominantly in hepatocytes. Of these, four had a hepatic iron index greater than 1. 9 and most seemed to have spur cell haemolytic anaemia.Mutation analysis for C282Y and H63D mutations was performed on DNA extracts from peripheral blood or explant liver. Spur cell haemolytic anaemia was diagnosed when the haemoglobin was 105 g/l in the presence of notable acanthocytosis.None of the eight patients with grade 3 or 4 hepatic iron had evidence of the C282Y mutation. Two of the eight were heterozygous for H63D. None of the remaining 28 patients tested showed homozygous HFE mutations. Spur cell anaemia was present in six of the eight patients with heavy iron deposition and only one of the remaining patients.The HFE mutation was not present in these patients with advanced ALD and heavy iron loading. Spur cell haemolytic anaemia provides an alternative potential mechanism for the heavy iron loading." @default.
• W2129343311 created "2016-06-24" @default.
• W2129343311 creator A5017152356 @default.
• W2129343311 creator A5017483194 @default.
• W2129343311 creator A5052118238 @default.
• W2129343311 creator A5063583921 @default.
• W2129343311 creator A5065923165 @default.
• W2129343311 creator A5076303778 @default.
• W2129343311 creator A5084102651 @default.
• W2129343311 creator A5087756518 @default.
• W2129343311 creator A5091597673 @default.
• W2129343311 date "1998-04-01" @default.
• W2129343311 modified "2023-09-27" @default.
• W2129343311 title "Spur cell anemia and hepatic iron stores in patients with alcoholic liver disease undergoing orthotopic liver transplantation" @default.
• W2129343311 cites W1964680735 @default.
• W2129343311 cites W1999956739 @default.
• W2129343311 cites W2002605005 @default.
• W2129343311 cites W2007134203 @default.
• W2129343311 cites W2007224829 @default.
• W2129343311 cites W2027151038 @default.
• W2129343311 cites W2028107207 @default.
• W2129343311 cites W2052779919 @default.
• W2129343311 cites W2062402244 @default.
• W2129343311 cites W2068699645 @default.
• W2129343311 cites W2073843577 @default.
• W2129343311 cites W2080597450 @default.
• W2129343311 cites W2084009696 @default.
• W2129343311 cites W2086823635 @default.
• W2129343311 cites W2088195156 @default.
• W2129343311 cites W2121571764 @default.
• W2129343311 cites W2137766764 @default.
• W2129343311 cites W2141937988 @default.
• W2129343311 cites W2156289531 @default.
• W2129343311 cites W2163469200 @default.
• W2129343311 cites W2312518903 @default.
• W2129343311 cites W2314218964 @default.
• W2129343311 cites W2337117352 @default.
• W2129343311 cites W2337809958 @default.
• W2129343311 doi "https://doi.org/10.1016/s0016-5085(98)85357-2" @default.
• W2129343311 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1727602" @default.
• W2129343311 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10403746" @default.
• W2129343311 hasPublicationYear "1998" @default.
• W2129343311 type Work @default.
• W2129343311 sameAs 2129343311 @default.
• W2129343311 citedByCount "14" @default.
• W2129343311 countsByYear W21293433112016 @default.
• W2129343311 countsByYear W21293433112018 @default.
• W2129343311 countsByYear W21293433112020 @default.
• W2129343311 countsByYear W21293433112021 @default.
• W2129343311 countsByYear W21293433112023 @default.
• W2129343311 crossrefType "journal-article" @default.
• W2129343311 hasAuthorship W2129343311A5017152356 @default.
• W2129343311 hasAuthorship W2129343311A5017483194 @default.
• W2129343311 hasAuthorship W2129343311A5052118238 @default.
• W2129343311 hasAuthorship W2129343311A5063583921 @default.
• W2129343311 hasAuthorship W2129343311A5065923165 @default.
• W2129343311 hasAuthorship W2129343311A5076303778 @default.
• W2129343311 hasAuthorship W2129343311A5084102651 @default.
• W2129343311 hasAuthorship W2129343311A5087756518 @default.
• W2129343311 hasAuthorship W2129343311A5091597673 @default.
• W2129343311 hasConcept C126322002 @default.
• W2129343311 hasConcept C142724271 @default.
• W2129343311 hasConcept C22814914 @default.
• W2129343311 hasConcept C2776590208 @default.
• W2129343311 hasConcept C2777075537 @default.
• W2129343311 hasConcept C2777214474 @default.
• W2129343311 hasConcept C2777575235 @default.
• W2129343311 hasConcept C2778248108 @default.
• W2129343311 hasConcept C2778319317 @default.
• W2129343311 hasConcept C2779609443 @default.
• W2129343311 hasConcept C2779875672 @default.
• W2129343311 hasConcept C2780883591 @default.
• W2129343311 hasConcept C2911091166 @default.
• W2129343311 hasConcept C71924100 @default.
• W2129343311 hasConcept C90924648 @default.
• W2129343311 hasConceptScore W2129343311C126322002 @default.
• W2129343311 hasConceptScore W2129343311C142724271 @default.
• W2129343311 hasConceptScore W2129343311C22814914 @default.
• W2129343311 hasConceptScore W2129343311C2776590208 @default.
• W2129343311 hasConceptScore W2129343311C2777075537 @default.
• W2129343311 hasConceptScore W2129343311C2777214474 @default.
• W2129343311 hasConceptScore W2129343311C2777575235 @default.
• W2129343311 hasConceptScore W2129343311C2778248108 @default.
• W2129343311 hasConceptScore W2129343311C2778319317 @default.
• W2129343311 hasConceptScore W2129343311C2779609443 @default.
• W2129343311 hasConceptScore W2129343311C2779875672 @default.
• W2129343311 hasConceptScore W2129343311C2780883591 @default.
• W2129343311 hasConceptScore W2129343311C2911091166 @default.
• W2129343311 hasConceptScore W2129343311C71924100 @default.
• W2129343311 hasConceptScore W2129343311C90924648 @default.
• W2129343311 hasLocation W21293433111 @default.
• W2129343311 hasLocation W21293433112 @default.
• W2129343311 hasOpenAccess W2129343311 @default.
• W2129343311 hasPrimaryLocation W21293433111 @default.
• W2129343311 hasRelatedWork W1480007741 @default.
• W2129343311 hasRelatedWork W179337756 @default.
• W2129343311 hasRelatedWork W1949160556 @default.
• W2129343311 hasRelatedWork W1999956739 @default.

• next