FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2129350002> ?p ?o ?g. }

• W2129350002 endingPage "603" @default.
• W2129350002 startingPage "584" @default.
• W2129350002 abstract "In the retina of warm-blooded vertebrates, photoreceptors are specified many days before the onset of synaptogenesis and the expression of photopigments. The factors that regulate the maturation of photoreceptors in the developing retina remain unknown. We report here that photoreceptors transiently express LIM-domain transcription factors during the development of the chicken retina. We examined the differentiation of photoreceptors through the normal course of embryonic development and at the far periphery of the postnatal retina, where the differentiation of photoreceptors is slowed and persists across a spatial gradient. In the embryonic retina, we find visinin-positive photoreceptors that transiently express Islet2 and Lim3 starting at E8 and ending around E15, but persisting in far peripheral regions of the retina through the first 2 weeks of postnatal development. During early stages of photoreceptor maturation, there is coincident and transient expression of the LIM-domain factors with axonin1, a cell surface glycoprotein that is a member of the immunoglobulin superfamily. Coincident with the downregulation of Islet2 and Lim3, we find the upregulation of calbindin, red/green opsin, rhodopsin, and a synaptic marker in the outer plexiform layer (OPL; dystrophin). In the periphery of the postnatal retina, photoreceptors that express Islet2, Lim3, and axonin1 do not overlap with photoreceptors that express calbindin, red/green opsin, rhodopsin, and dystrophin. We propose that Islet2 and Lim3 may promote the expression of genes that are involved in the early stages of differentiation but may suppress the expression of genes that are required in the mature photoreceptors. J. Comp. Neurol. 506:584–603, 2008. © 2007 Wiley-Liss, Inc." @default.
• W2129350002 created "2016-06-24" @default.
• W2129350002 creator A5021402716 @default.
• W2129350002 creator A5052840139 @default.
• W2129350002 creator A5063139808 @default.
• W2129350002 creator A5071938054 @default.
• W2129350002 date "2008-02-01" @default.
• W2129350002 modified "2023-10-02" @default.
• W2129350002 title "Transient expression of LIM-domain transcription factors is coincident with delayed maturation of photoreceptors in the chicken retina" @default.
• W2129350002 cites W1487433380 @default.
• W2129350002 cites W1488709092 @default.
• W2129350002 cites W1520825673 @default.
• W2129350002 cites W1533241880 @default.
• W2129350002 cites W1573546761 @default.
• W2129350002 cites W1587507760 @default.
• W2129350002 cites W1942735643 @default.
• W2129350002 cites W1963802469 @default.
• W2129350002 cites W1966563415 @default.
• W2129350002 cites W1969751305 @default.
• W2129350002 cites W1973632581 @default.
• W2129350002 cites W1975395796 @default.
• W2129350002 cites W1976616514 @default.
• W2129350002 cites W1976833281 @default.
• W2129350002 cites W1978511926 @default.
• W2129350002 cites W1982630660 @default.
• W2129350002 cites W1986727202 @default.
• W2129350002 cites W1997668305 @default.
• W2129350002 cites W1998625959 @default.
• W2129350002 cites W2000067302 @default.
• W2129350002 cites W2000700429 @default.
• W2129350002 cites W2001025502 @default.
• W2129350002 cites W2001296529 @default.
• W2129350002 cites W2006551649 @default.
• W2129350002 cites W2007238959 @default.
• W2129350002 cites W2008277743 @default.
• W2129350002 cites W2021189161 @default.
• W2129350002 cites W2029390749 @default.
• W2129350002 cites W2031880789 @default.
• W2129350002 cites W2031927234 @default.
• W2129350002 cites W2033508386 @default.
• W2129350002 cites W2033972057 @default.
• W2129350002 cites W2046399652 @default.
• W2129350002 cites W2048249023 @default.
• W2129350002 cites W2052035608 @default.
• W2129350002 cites W2056846577 @default.
• W2129350002 cites W2058403725 @default.
• W2129350002 cites W2061033163 @default.
• W2129350002 cites W2065473909 @default.
• W2129350002 cites W2067114202 @default.
• W2129350002 cites W2070625860 @default.
• W2129350002 cites W2076521138 @default.
• W2129350002 cites W2084582407 @default.
• W2129350002 cites W2084644999 @default.
• W2129350002 cites W2085924238 @default.
• W2129350002 cites W2090923280 @default.
• W2129350002 cites W2102567777 @default.
• W2129350002 cites W2105995626 @default.
• W2129350002 cites W2109876648 @default.
• W2129350002 cites W2111434225 @default.
• W2129350002 cites W2119675301 @default.
• W2129350002 cites W2122555407 @default.
• W2129350002 cites W2130966063 @default.
• W2129350002 cites W2141150300 @default.
• W2129350002 cites W2142352838 @default.
• W2129350002 cites W2143952717 @default.
• W2129350002 cites W2153073720 @default.
• W2129350002 cites W2154702270 @default.
• W2129350002 cites W2160391559 @default.
• W2129350002 cites W2169344378 @default.
• W2129350002 cites W2121865262 @default.
• W2129350002 doi "https://doi.org/10.1002/cne.21578" @default.
• W2129350002 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2774723" @default.
• W2129350002 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18072193" @default.
• W2129350002 hasPublicationYear "2008" @default.
• W2129350002 type Work @default.
• W2129350002 sameAs 2129350002 @default.
• W2129350002 citedByCount "52" @default.
• W2129350002 countsByYear W21293500022012 @default.
• W2129350002 countsByYear W21293500022013 @default.
• W2129350002 countsByYear W21293500022014 @default.
• W2129350002 countsByYear W21293500022015 @default.
• W2129350002 countsByYear W21293500022017 @default.
• W2129350002 countsByYear W21293500022018 @default.
• W2129350002 countsByYear W21293500022019 @default.
• W2129350002 countsByYear W21293500022020 @default.
• W2129350002 countsByYear W21293500022021 @default.
• W2129350002 countsByYear W21293500022022 @default.
• W2129350002 countsByYear W21293500022023 @default.
• W2129350002 crossrefType "journal-article" @default.
• W2129350002 hasAuthorship W2129350002A5021402716 @default.
• W2129350002 hasAuthorship W2129350002A5052840139 @default.
• W2129350002 hasAuthorship W2129350002A5063139808 @default.
• W2129350002 hasAuthorship W2129350002A5071938054 @default.
• W2129350002 hasBestOaLocation W21293500022 @default.
• W2129350002 hasConcept C104317684 @default.
• W2129350002 hasConcept C127561419 @default.
• W2129350002 hasConcept C145103041 @default.
• W2129350002 hasConcept C169760540 @default.

• next