Matches in SemOpenAlex for { <https://semopenalex.org/work/W2129354881> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2129354881 endingPage "675" @default.
- W2129354881 startingPage "665" @default.
- W2129354881 abstract "Tyrosine kinase inhibitors (TKIs) are the mainstay of the management of advanced gastrointestinal stromal tumors (GISTs). Currently, imatinib, sunitinib and regorafenib are approved treatments for advanced GISTs. However, most standard therapies eventually stop working due to polyclonal evolution of the disease, which results in TKI resistance and overall disease progression. For patients with refractory GISTs after progression on all approved TKIs, resumption of previously effective TKIs may have clinical benefit. However, no randomized trial had been performed to support TKI reuse in patients with advanced GISTs. Recently, a placebo-controlled randomized Phase III trial (RIGHT) found that imatinib resumption significantly prolonged progression-free survival in patients with TKI-refractory GISTs versus placebo. The details of the RIGHT trial and its clinical implications are reviewed here." @default.
- W2129354881 created "2016-06-24" @default.
- W2129354881 creator A5005925636 @default.
- W2129354881 creator A5090754319 @default.
- W2129354881 date "2015-07-01" @default.
- W2129354881 modified "2023-09-25" @default.
- W2129354881 title "Rechallenge with imatinib in advanced gastrointestinal stromal tumors: clinical implications of the RIGHT trial" @default.
- W2129354881 cites W1741335535 @default.
- W2129354881 cites W1967431262 @default.
- W2129354881 cites W1971554504 @default.
- W2129354881 cites W1978304226 @default.
- W2129354881 cites W1982326378 @default.
- W2129354881 cites W1995930366 @default.
- W2129354881 cites W2015015957 @default.
- W2129354881 cites W2019607817 @default.
- W2129354881 cites W2035481521 @default.
- W2129354881 cites W2036092673 @default.
- W2129354881 cites W2045992174 @default.
- W2129354881 cites W2068633458 @default.
- W2129354881 cites W2115504770 @default.
- W2129354881 cites W2116922255 @default.
- W2129354881 cites W2129931005 @default.
- W2129354881 cites W2137086207 @default.
- W2129354881 cites W2139248078 @default.
- W2129354881 cites W2139511378 @default.
- W2129354881 cites W2156143871 @default.
- W2129354881 cites W2156834559 @default.
- W2129354881 cites W2160373161 @default.
- W2129354881 cites W2163672915 @default.
- W2129354881 cites W2167903658 @default.
- W2129354881 cites W2169363650 @default.
- W2129354881 cites W2324850882 @default.
- W2129354881 cites W4210999713 @default.
- W2129354881 cites W4238208852 @default.
- W2129354881 doi "https://doi.org/10.4155/cli.15.26" @default.
- W2129354881 hasPublicationYear "2015" @default.
- W2129354881 type Work @default.
- W2129354881 sameAs 2129354881 @default.
- W2129354881 citedByCount "1" @default.
- W2129354881 countsByYear W21293548812022 @default.
- W2129354881 crossrefType "journal-article" @default.
- W2129354881 hasAuthorship W2129354881A5005925636 @default.
- W2129354881 hasAuthorship W2129354881A5090754319 @default.
- W2129354881 hasConcept C126322002 @default.
- W2129354881 hasConcept C142724271 @default.
- W2129354881 hasConcept C143998085 @default.
- W2129354881 hasConcept C16930146 @default.
- W2129354881 hasConcept C2775922572 @default.
- W2129354881 hasConcept C2777007597 @default.
- W2129354881 hasConcept C2777583451 @default.
- W2129354881 hasConcept C2778729363 @default.
- W2129354881 hasConcept C3019892230 @default.
- W2129354881 hasConcept C502942594 @default.
- W2129354881 hasConcept C535046627 @default.
- W2129354881 hasConcept C71924100 @default.
- W2129354881 hasConceptScore W2129354881C126322002 @default.
- W2129354881 hasConceptScore W2129354881C142724271 @default.
- W2129354881 hasConceptScore W2129354881C143998085 @default.
- W2129354881 hasConceptScore W2129354881C16930146 @default.
- W2129354881 hasConceptScore W2129354881C2775922572 @default.
- W2129354881 hasConceptScore W2129354881C2777007597 @default.
- W2129354881 hasConceptScore W2129354881C2777583451 @default.
- W2129354881 hasConceptScore W2129354881C2778729363 @default.
- W2129354881 hasConceptScore W2129354881C3019892230 @default.
- W2129354881 hasConceptScore W2129354881C502942594 @default.
- W2129354881 hasConceptScore W2129354881C535046627 @default.
- W2129354881 hasConceptScore W2129354881C71924100 @default.
- W2129354881 hasIssue "7" @default.
- W2129354881 hasLocation W21293548811 @default.
- W2129354881 hasOpenAccess W2129354881 @default.
- W2129354881 hasPrimaryLocation W21293548811 @default.
- W2129354881 hasRelatedWork W1968814687 @default.
- W2129354881 hasRelatedWork W1973863491 @default.
- W2129354881 hasRelatedWork W1980194317 @default.
- W2129354881 hasRelatedWork W2005081096 @default.
- W2129354881 hasRelatedWork W2079642245 @default.
- W2129354881 hasRelatedWork W2367850073 @default.
- W2129354881 hasRelatedWork W2809726097 @default.
- W2129354881 hasRelatedWork W3030442802 @default.
- W2129354881 hasRelatedWork W3117440509 @default.
- W2129354881 hasRelatedWork W3127233814 @default.
- W2129354881 hasVolume "5" @default.
- W2129354881 isParatext "false" @default.
- W2129354881 isRetracted "false" @default.
- W2129354881 magId "2129354881" @default.
- W2129354881 workType "article" @default.