FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2129367391> ?p ?o ?g. }

• W2129367391 endingPage "366" @default.
• W2129367391 startingPage "344" @default.
• W2129367391 abstract "The influence of different anesthetics on the depressor and pressor as well as the lactic acid stimulating effects of adrenaline were investigated in cats and compared with the corresponding effects in unanesthetized animals. Adrenaline was infused intravenously for 5 minutes in increasing doses ranging from 0.1 to 24.3 μg per kg body weight per minute. In unanesthetized animals the depressor effect was very slight, although adrenaline reduced the total peripheral resistance; this probably because the blood-pressure regulation was better than in the anesthetized animals. In most of the latter the depressor effect emerged, but its magnitude varied considerably according to the anesthetic employed. Broadly speaking, the depressor effect showed a statistically significant correlation both to adrenaline's ability to increase the lactic acid content of the blood and to the basal blood-pressure level. The same factors that amplified the depressor effect of adrenaline weakened its pressor effect. The latter was negatively correlated to the basal blood-pressure level and to the lactic acid producing capacity of adrenaline. Further, the anesthetic had a direct inhibitory effect on adrenaline's vasoconstrictor action. In the individual cases the influence of the different anesthetics on adrenaline's circulatory effect was explained as follows. Ether amplified the lactic acid production and raised the basal blood pressure in relation to adrenaline's effect on unanesthetized animals, the depressor effect was very pronounced and the pressor effect greatly weakened. Urethane did not influence the lactic acid production, but elevated the basal blood pressure; the depressor effect was distinct but the pressor effect weakened. Evipan did not demonstrably influence either the lactic acid production or the basal blood pressure; the depressor effect was somewhat greater and the pressor effect somewhat less than in unanesthetized animals. Dial inhibited the lactic acid production without definitely influencing the basal blood pressure; the depressor effect was weak but the pressor effect amplified. Chlo-ralose inhibited the lactic acid producing action of adrenaline but concurrently raised the basal blood pressure; these effects on adrenaline's action tended to counterbalance each other. Noradrenaline had neither a lactic acid stimulating nor a depressor effect on ether-anesthetized cats." @default.
• W2129367391 created "2016-06-24" @default.
• W2129367391 creator A5034701224 @default.
• W2129367391 date "1957-12-01" @default.
• W2129367391 modified "2023-10-16" @default.
• W2129367391 title "The Mechanism of the Vasodilator Effect of Adrenaline. II. Influence of Anesthetics on the Depressor, Pressor and Lactic Acid Stimulating Effects of Adrenaline." @default.
• W2129367391 cites W1973469830 @default.
• W2129367391 cites W1984705663 @default.
• W2129367391 cites W2023379767 @default.
• W2129367391 cites W2031588753 @default.
• W2129367391 cites W2069687066 @default.
• W2129367391 cites W2266073327 @default.
• W2129367391 cites W2339476521 @default.
• W2129367391 cites W2395218095 @default.
• W2129367391 cites W2420696468 @default.
• W2129367391 cites W2424492893 @default.
• W2129367391 cites W2911993437 @default.
• W2129367391 cites W3158700751 @default.
• W2129367391 cites W4244211643 @default.
• W2129367391 doi "https://doi.org/10.1111/j.1748-1716.1957.tb01503.x" @default.
• W2129367391 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/13478502" @default.
• W2129367391 hasPublicationYear "1957" @default.
• W2129367391 type Work @default.
• W2129367391 sameAs 2129367391 @default.
• W2129367391 citedByCount "13" @default.
• W2129367391 crossrefType "journal-article" @default.
• W2129367391 hasAuthorship W2129367391A5034701224 @default.
• W2129367391 hasConcept C120770815 @default.
• W2129367391 hasConcept C126322002 @default.
• W2129367391 hasConcept C134018914 @default.
• W2129367391 hasConcept C185592680 @default.
• W2129367391 hasConcept C2775859304 @default.
• W2129367391 hasConcept C2775920511 @default.
• W2129367391 hasConcept C2777953023 @default.
• W2129367391 hasConcept C2778024521 @default.
• W2129367391 hasConcept C2778162923 @default.
• W2129367391 hasConcept C2779306644 @default.
• W2129367391 hasConcept C3019263340 @default.
• W2129367391 hasConcept C42219234 @default.
• W2129367391 hasConcept C523546767 @default.
• W2129367391 hasConcept C54355233 @default.
• W2129367391 hasConcept C71924100 @default.
• W2129367391 hasConcept C72859922 @default.
• W2129367391 hasConcept C84393581 @default.
• W2129367391 hasConcept C86803240 @default.
• W2129367391 hasConceptScore W2129367391C120770815 @default.
• W2129367391 hasConceptScore W2129367391C126322002 @default.
• W2129367391 hasConceptScore W2129367391C134018914 @default.
• W2129367391 hasConceptScore W2129367391C185592680 @default.
• W2129367391 hasConceptScore W2129367391C2775859304 @default.
• W2129367391 hasConceptScore W2129367391C2775920511 @default.
• W2129367391 hasConceptScore W2129367391C2777953023 @default.
• W2129367391 hasConceptScore W2129367391C2778024521 @default.
• W2129367391 hasConceptScore W2129367391C2778162923 @default.
• W2129367391 hasConceptScore W2129367391C2779306644 @default.
• W2129367391 hasConceptScore W2129367391C3019263340 @default.
• W2129367391 hasConceptScore W2129367391C42219234 @default.
• W2129367391 hasConceptScore W2129367391C523546767 @default.
• W2129367391 hasConceptScore W2129367391C54355233 @default.
• W2129367391 hasConceptScore W2129367391C71924100 @default.
• W2129367391 hasConceptScore W2129367391C72859922 @default.
• W2129367391 hasConceptScore W2129367391C84393581 @default.
• W2129367391 hasConceptScore W2129367391C86803240 @default.
• W2129367391 hasIssue "4" @default.
• W2129367391 hasLocation W21293673911 @default.
• W2129367391 hasLocation W21293673912 @default.
• W2129367391 hasOpenAccess W2129367391 @default.
• W2129367391 hasPrimaryLocation W21293673911 @default.
• W2129367391 hasRelatedWork W1980042062 @default.
• W2129367391 hasRelatedWork W2026413826 @default.
• W2129367391 hasRelatedWork W2038512896 @default.
• W2129367391 hasRelatedWork W2044985824 @default.
• W2129367391 hasRelatedWork W2052457305 @default.
• W2129367391 hasRelatedWork W2054491688 @default.
• W2129367391 hasRelatedWork W2054777415 @default.
• W2129367391 hasRelatedWork W2089092795 @default.
• W2129367391 hasRelatedWork W2170936196 @default.
• W2129367391 hasRelatedWork W2460584456 @default.
• W2129367391 hasVolume "40" @default.
• W2129367391 isParatext "false" @default.
• W2129367391 isRetracted "false" @default.
• W2129367391 magId "2129367391" @default.
• W2129367391 workType "article" @default.