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- W2129374429 abstract "The Gag protein of Rous sarcoma virus (RSV) can direct particle assembly and budding at the plasma membrane independently of the other virus-encoded products. A previous deletion analysis has suggested that the first 86 amino acids of RSV Gag constitute a large membrane-binding domain that is absolutely required for these processes. To test this hypothesis, we inserted these residues in place of the N-terminal membrane-binding domain of the pp60v-src, a transforming protein whose biological activity requires plasma membrane localization. The ability of the Src chimera to induce cellular transformation suggests that the RSV sequence indeed contains an independent, functional domain." @default.
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- W2129374429 date "1996-04-01" @default.
- W2129374429 modified "2023-09-24" @default.
- W2129374429 title "The membrane-binding domain of the Rous sarcoma virus Gag protein" @default.
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- W2129374429 doi "https://doi.org/10.1128/jvi.70.4.2664-2668.1996" @default.
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