FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2129402364> ?p ?o ?g. }

• W2129402364 endingPage "1344" @default.
• W2129402364 startingPage "1337" @default.
• W2129402364 abstract "Mice that were intranasally immunized with different influenza A virus hemagglutinins (HA), derived from PR8 (H1N1), A/Yamagata (H1N1) or A/Fukuoka (H3N2) virus, together with cholera toxin B subunit as an adjuvant, were examined for protection against PR8 infection; PR8 HA and A/Yamagata HA immunization conferred complete protection, while A/Fukuoka HA immunization failed to confer protection. In parallel with protection, PR8 HA-, A/Yamagata HA-, and A/Fukuoka HA-immunized mice produced a high, a moderate and a low level of PR8 HA-reactive IgA in the respiratory tract, respectively. These IgA antibodies were not only higher in content in the nasal secretions, but also more cross-reactive than IgG. The purified IgA antibodies from respiratory tract washings of PR8 HA-immunized mice, which contained the HA-specific IgA corresponding to the amount deteced in the nasal wash, were able to protect mice from PR8 challenge when transferred to the respiratory tract of naive mice. The transfer of IgA from A/Yamagata HA-immunized mice also afforded cross-protection against PR8 infection, whereas the IgA from A/Fukuoka HA-immunized mice failed to provide protection. The ability of transferred IgA to prevent viral infection was dependent on the amount of HA-reactive IgA remaining in the respiratory tract of the host at the time of infection. These experiments directly demonstrate that IgA antibodies to influenza A virus HA by themselves play a pivotal role in defence not only against homologous virus infection, but also against heterologous drift virus infection at the respiratory mucosa, the portal of entry for the viruses." @default.
• W2129402364 created "2016-06-24" @default.
• W2129402364 creator A5007362359 @default.
• W2129402364 creator A5007921825 @default.
• W2129402364 creator A5044176693 @default.
• W2129402364 creator A5044309425 @default.
• W2129402364 creator A5055542819 @default.
• W2129402364 creator A5063817865 @default.
• W2129402364 creator A5083371290 @default.
• W2129402364 date "1991-06-01" @default.
• W2129402364 modified "2023-09-27" @default.
• W2129402364 title "Cross-protection against influenza A virus infection by passively transferred respiratory tract IgA antibodies to different hemagglutinin molecules" @default.
• W2129402364 cites W1502859775 @default.
• W2129402364 cites W1572227522 @default.
• W2129402364 cites W1618733816 @default.
• W2129402364 cites W1655175605 @default.
• W2129402364 cites W1808739935 @default.
• W2129402364 cites W1811768630 @default.
• W2129402364 cites W1897992263 @default.
• W2129402364 cites W1907805545 @default.
• W2129402364 cites W1983826199 @default.
• W2129402364 cites W1988725751 @default.
• W2129402364 cites W1989908697 @default.
• W2129402364 cites W2001118304 @default.
• W2129402364 cites W2001772964 @default.
• W2129402364 cites W2006453243 @default.
• W2129402364 cites W2024619850 @default.
• W2129402364 cites W2043831246 @default.
• W2129402364 cites W2051906249 @default.
• W2129402364 cites W2058944751 @default.
• W2129402364 cites W2062207296 @default.
• W2129402364 cites W2063036448 @default.
• W2129402364 cites W2117355212 @default.
• W2129402364 cites W2130468660 @default.
• W2129402364 cites W2150853896 @default.
• W2129402364 cites W2154116964 @default.
• W2129402364 cites W2157547565 @default.
• W2129402364 cites W2161030974 @default.
• W2129402364 cites W2164926164 @default.
• W2129402364 cites W2167409545 @default.
• W2129402364 cites W2171149861 @default.
• W2129402364 cites W2314977185 @default.
• W2129402364 doi "https://doi.org/10.1002/eji.1830210602" @default.
• W2129402364 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1646112" @default.
• W2129402364 hasPublicationYear "1991" @default.
• W2129402364 type Work @default.
• W2129402364 sameAs 2129402364 @default.
• W2129402364 citedByCount "144" @default.
• W2129402364 countsByYear W21294023642012 @default.
• W2129402364 countsByYear W21294023642013 @default.
• W2129402364 countsByYear W21294023642014 @default.
• W2129402364 countsByYear W21294023642015 @default.
• W2129402364 countsByYear W21294023642016 @default.
• W2129402364 countsByYear W21294023642017 @default.
• W2129402364 countsByYear W21294023642018 @default.
• W2129402364 countsByYear W21294023642019 @default.
• W2129402364 countsByYear W21294023642020 @default.
• W2129402364 countsByYear W21294023642021 @default.
• W2129402364 countsByYear W21294023642022 @default.
• W2129402364 countsByYear W21294023642023 @default.
• W2129402364 crossrefType "journal-article" @default.
• W2129402364 hasAuthorship W2129402364A5007362359 @default.
• W2129402364 hasAuthorship W2129402364A5007921825 @default.
• W2129402364 hasAuthorship W2129402364A5044176693 @default.
• W2129402364 hasAuthorship W2129402364A5044309425 @default.
• W2129402364 hasAuthorship W2129402364A5055542819 @default.
• W2129402364 hasAuthorship W2129402364A5063817865 @default.
• W2129402364 hasAuthorship W2129402364A5083371290 @default.
• W2129402364 hasConcept C105702510 @default.
• W2129402364 hasConcept C159047783 @default.
• W2129402364 hasConcept C159654299 @default.
• W2129402364 hasConcept C203014093 @default.
• W2129402364 hasConcept C2522874641 @default.
• W2129402364 hasConcept C2777546802 @default.
• W2129402364 hasConcept C2778692840 @default.
• W2129402364 hasConcept C2779102806 @default.
• W2129402364 hasConcept C2779644171 @default.
• W2129402364 hasConcept C2780801004 @default.
• W2129402364 hasConcept C2780898057 @default.
• W2129402364 hasConcept C2781416681 @default.
• W2129402364 hasConcept C534529494 @default.
• W2129402364 hasConcept C85663871 @default.
• W2129402364 hasConcept C86803240 @default.
• W2129402364 hasConcept C89423630 @default.
• W2129402364 hasConceptScore W2129402364C105702510 @default.
• W2129402364 hasConceptScore W2129402364C159047783 @default.
• W2129402364 hasConceptScore W2129402364C159654299 @default.
• W2129402364 hasConceptScore W2129402364C203014093 @default.
• W2129402364 hasConceptScore W2129402364C2522874641 @default.
• W2129402364 hasConceptScore W2129402364C2777546802 @default.
• W2129402364 hasConceptScore W2129402364C2778692840 @default.
• W2129402364 hasConceptScore W2129402364C2779102806 @default.
• W2129402364 hasConceptScore W2129402364C2779644171 @default.
• W2129402364 hasConceptScore W2129402364C2780801004 @default.
• W2129402364 hasConceptScore W2129402364C2780898057 @default.
• W2129402364 hasConceptScore W2129402364C2781416681 @default.
• W2129402364 hasConceptScore W2129402364C534529494 @default.
• W2129402364 hasConceptScore W2129402364C85663871 @default.

• next