Matches in SemOpenAlex for { <https://semopenalex.org/work/W2129449690> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2129449690 abstract "Early clinical studies investigating the role of angiotensin-converting enzyme (ACE) inhibitors in the treatment of heart failure unexpectedly demonstrated a possible reduction in coronary heart disease endpoints. Two large scale clinical trials, HOPE and EUROPA, both studies in patients with coronary artery disease (CAD) but without clinical evidence of heart failure, showed a highly significant improvement in coronary heart disease outcomes on treatment with ramipril and perindopril, respectively, in contrast, in a similar population, PEACE was unable to demonstrate such benefit with trandolapril. Meta-analyses of all trials involving ACE-inhibitors showed a highly significant improvement in coronary heart disease endpoints. Current ESC guidelines recommend ACE-inhibitor therapy in CAD patients with co-existing indications for ACE-inhibitors, such as hypertension, heart failure, left ventricular dysfunction, prior MI was left ventricular dysfunction, or diabetes (class I, level of evidence A). These guidelines also recommend ACE-inhibitor therapy in all patients with angina and proven coronary disease (class IIa, level of evidence B). However, in angina patients without independent indication for ACE-inhibitor treatment, the anticipated benefit should be weighted against the costs and risks of side effects; in these patients, only agents and doses of proven efficacy for secondary prevention should be employed." @default.
- W2129449690 created "2016-06-24" @default.
- W2129449690 creator A5007737202 @default.
- W2129449690 creator A5018419311 @default.
- W2129449690 creator A5062655570 @default.
- W2129449690 creator A5072856915 @default.
- W2129449690 date "2006-08-09" @default.
- W2129449690 modified "2023-10-16" @default.
- W2129449690 title "Should angiotensin-converting enzyme-inhibitors be used to improve outcome in patients with coronary artery disease and 'preserved' left ventricular function?" @default.
- W2129449690 cites W1680510 @default.
- W2129449690 cites W175023260 @default.
- W2129449690 cites W180946569 @default.
- W2129449690 cites W1984456541 @default.
- W2129449690 cites W1988569489 @default.
- W2129449690 cites W1997180684 @default.
- W2129449690 cites W200018444 @default.
- W2129449690 cites W2023755744 @default.
- W2129449690 cites W2049394372 @default.
- W2129449690 cites W2072952396 @default.
- W2129449690 cites W2103648677 @default.
- W2129449690 cites W2106244081 @default.
- W2129449690 cites W2120934006 @default.
- W2129449690 cites W2121504382 @default.
- W2129449690 cites W2125730125 @default.
- W2129449690 cites W2135262484 @default.
- W2129449690 cites W2145981382 @default.
- W2129449690 cites W2161372989 @default.
- W2129449690 cites W2305118939 @default.
- W2129449690 cites W2326354230 @default.
- W2129449690 cites W2946929330 @default.
- W2129449690 cites W2244522312 @default.
- W2129449690 doi "https://doi.org/10.1093/eurheartj/ehl122" @default.
- W2129449690 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16905555" @default.
- W2129449690 hasPublicationYear "2006" @default.
- W2129449690 type Work @default.
- W2129449690 sameAs 2129449690 @default.
- W2129449690 citedByCount "15" @default.
- W2129449690 countsByYear W21294496902014 @default.
- W2129449690 crossrefType "journal-article" @default.
- W2129449690 hasAuthorship W2129449690A5007737202 @default.
- W2129449690 hasAuthorship W2129449690A5018419311 @default.
- W2129449690 hasAuthorship W2129449690A5062655570 @default.
- W2129449690 hasAuthorship W2129449690A5072856915 @default.
- W2129449690 hasBestOaLocation W21294496901 @default.
- W2129449690 hasConcept C126322002 @default.
- W2129449690 hasConcept C134018914 @default.
- W2129449690 hasConcept C164705383 @default.
- W2129449690 hasConcept C27016395 @default.
- W2129449690 hasConcept C2778198053 @default.
- W2129449690 hasConcept C2778213512 @default.
- W2129449690 hasConcept C2778425758 @default.
- W2129449690 hasConcept C2778728240 @default.
- W2129449690 hasConcept C2779200603 @default.
- W2129449690 hasConcept C2779611605 @default.
- W2129449690 hasConcept C2779888176 @default.
- W2129449690 hasConcept C2908647359 @default.
- W2129449690 hasConcept C500558357 @default.
- W2129449690 hasConcept C555293320 @default.
- W2129449690 hasConcept C71924100 @default.
- W2129449690 hasConcept C84393581 @default.
- W2129449690 hasConcept C99454951 @default.
- W2129449690 hasConceptScore W2129449690C126322002 @default.
- W2129449690 hasConceptScore W2129449690C134018914 @default.
- W2129449690 hasConceptScore W2129449690C164705383 @default.
- W2129449690 hasConceptScore W2129449690C27016395 @default.
- W2129449690 hasConceptScore W2129449690C2778198053 @default.
- W2129449690 hasConceptScore W2129449690C2778213512 @default.
- W2129449690 hasConceptScore W2129449690C2778425758 @default.
- W2129449690 hasConceptScore W2129449690C2778728240 @default.
- W2129449690 hasConceptScore W2129449690C2779200603 @default.
- W2129449690 hasConceptScore W2129449690C2779611605 @default.
- W2129449690 hasConceptScore W2129449690C2779888176 @default.
- W2129449690 hasConceptScore W2129449690C2908647359 @default.
- W2129449690 hasConceptScore W2129449690C500558357 @default.
- W2129449690 hasConceptScore W2129449690C555293320 @default.
- W2129449690 hasConceptScore W2129449690C71924100 @default.
- W2129449690 hasConceptScore W2129449690C84393581 @default.
- W2129449690 hasConceptScore W2129449690C99454951 @default.
- W2129449690 hasLocation W21294496901 @default.
- W2129449690 hasLocation W21294496902 @default.
- W2129449690 hasOpenAccess W2129449690 @default.
- W2129449690 hasPrimaryLocation W21294496901 @default.
- W2129449690 hasRelatedWork W1880353971 @default.
- W2129449690 hasRelatedWork W2028956624 @default.
- W2129449690 hasRelatedWork W2034220803 @default.
- W2129449690 hasRelatedWork W2066929182 @default.
- W2129449690 hasRelatedWork W2081820212 @default.
- W2129449690 hasRelatedWork W2120528784 @default.
- W2129449690 hasRelatedWork W2129449690 @default.
- W2129449690 hasRelatedWork W2419053307 @default.
- W2129449690 hasRelatedWork W2012852867 @default.
- W2129449690 hasRelatedWork W3145006148 @default.
- W2129449690 isParatext "false" @default.
- W2129449690 isRetracted "false" @default.
- W2129449690 magId "2129449690" @default.
- W2129449690 workType "article" @default.