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- W2129463218 abstract "Abstract Previously we identified a novel antigenic open reading frame (ORF), designated as ORF‐14, on the RD1 region of Mycobacterium tuberculosis that was not originally predicted by Mahairas or by annotation of the M. tuberculosis H37 Rv genome. Here we show that anti‐ORF‐14 antibodies either from mice immunized with recombinant ORF‐14 protein or isolated from serum samples from tuberculosis patients, react with a protein in culture filtrate but not in cytoplasmic or cell wall fractions from M. tuberculosis . Our data indicate that the ORF‐14 protein is expressed as a secreted protein, representing one more secreted protein antigen not previously identified by genomics." @default.
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- W2129463218 date "2007-06-27" @default.
- W2129463218 modified "2023-10-12" @default.
- W2129463218 title "Demonstration of In vivo Expression of a Hypothetical Open Reading Frame (ORF-14) Encoded by the RD1 Region of Mycobacterium tuberculosis" @default.
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- W2129463218 doi "https://doi.org/10.1111/j.1365-3083.2007.01961.x" @default.
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