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- W2129491010 abstract "Soluble adenylyl cyclase (sAC) is poised to play multiple physiological roles as an acid/base (A/B) sensor in aquatic organisms. Many of these roles are probably similar to those in mammals; a striking example is the evolutionary conservation of a mechanism involving sAC, carbonic anhydrase and vacuolar H⁺-ATPase that acts as a sensor system and regulator of extracellular A/B in shark gills and mammalian epididymis and kidney. Additionally, the aquatic environment presents unique A/B and physiological challenges; therefore, sACs from aquatic organisms have likely evolved distinct kinetic properties as well as distinct physiological roles. sACs from aquatic organisms offer an excellent opportunity for studying the evolution of A/B sensing at both the molecular and whole organism levels. Moreover, this information could help understand and predict organismal responses to environmental stress based on mechanistic models.This article is part of a Special Issue entitled The Role of Soluble Adenylyl Cyclase in Health and Disease, guest edited by J. Buck and L. R. Levin." @default.
- W2129491010 created "2016-06-24" @default.
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- W2129491010 date "2014-12-01" @default.
- W2129491010 modified "2023-10-06" @default.
- W2129491010 title "sAC from aquatic organisms as a model to study the evolution of acid/base sensing" @default.
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- W2129491010 cites W1970061319 @default.
- W2129491010 cites W1972442071 @default.
- W2129491010 cites W1974031867 @default.
- W2129491010 cites W1974383861 @default.
- W2129491010 cites W1974514289 @default.
- W2129491010 cites W1980934904 @default.
- W2129491010 cites W1986742807 @default.
- W2129491010 cites W1986985081 @default.
- W2129491010 cites W1988655765 @default.
- W2129491010 cites W1992403833 @default.
- W2129491010 cites W1998310999 @default.
- W2129491010 cites W1999992114 @default.
- W2129491010 cites W2003769012 @default.
- W2129491010 cites W2004936317 @default.
- W2129491010 cites W2011398547 @default.
- W2129491010 cites W2016935803 @default.
- W2129491010 cites W2018229529 @default.
- W2129491010 cites W2018849882 @default.
- W2129491010 cites W2028718122 @default.
- W2129491010 cites W2030024497 @default.
- W2129491010 cites W2033362878 @default.
- W2129491010 cites W2038142046 @default.
- W2129491010 cites W2039031569 @default.
- W2129491010 cites W2039444927 @default.
- W2129491010 cites W2040841039 @default.
- W2129491010 cites W2052877849 @default.
- W2129491010 cites W2058002822 @default.
- W2129491010 cites W2063496837 @default.
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- W2129491010 doi "https://doi.org/10.1016/j.bbadis.2014.06.021" @default.
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