Matches in SemOpenAlex for { <https://semopenalex.org/work/W2129501023> ?p ?o ?g. }
- W2129501023 endingPage "1262" @default.
- W2129501023 startingPage "1258" @default.
- W2129501023 abstract "Because of a critical shortage in suitable organs, many patients with terminal liver disease die each year before liver transplantation can be performed. Transplantation of isolated hepatocytes has been proposed for the temporary metabolic support of patients awaiting liver transplantation or spontaneous reversion of their liver disease. A major limitation of this form of therapy is the present inability to isolate an adequate number of transplantable hepatocytes. A highly differentiated cell line, NKNT-3, was generated by retroviral transfer in normal primary adult human hepatocytes of an immortalizing gene that can be subsequently and completely excised by Cre/Lox site-specific recombination. When transplanted into the spleen of rats under transient immunosuppression, reversibly immortalized NKNT-3 cells provided life-saving metabolic support during acute liver failure induced by 90% hepatectomy." @default.
- W2129501023 created "2016-06-24" @default.
- W2129501023 creator A5003021411 @default.
- W2129501023 creator A5020887225 @default.
- W2129501023 creator A5021126434 @default.
- W2129501023 creator A5021973822 @default.
- W2129501023 creator A5029014038 @default.
- W2129501023 creator A5057211368 @default.
- W2129501023 creator A5059745520 @default.
- W2129501023 creator A5067360623 @default.
- W2129501023 creator A5068717107 @default.
- W2129501023 creator A5069853713 @default.
- W2129501023 creator A5078855662 @default.
- W2129501023 date "2000-02-18" @default.
- W2129501023 modified "2023-10-12" @default.
- W2129501023 title "Prevention of Acute Liver Failure in Rats with Reversibly Immortalized Human Hepatocytes" @default.
- W2129501023 cites W1480965863 @default.
- W2129501023 cites W1979686921 @default.
- W2129501023 cites W1981581728 @default.
- W2129501023 cites W1986942920 @default.
- W2129501023 cites W1991625157 @default.
- W2129501023 cites W2005275397 @default.
- W2129501023 cites W2026796585 @default.
- W2129501023 cites W2042962210 @default.
- W2129501023 cites W2043300139 @default.
- W2129501023 cites W2070991874 @default.
- W2129501023 cites W2076129653 @default.
- W2129501023 cites W2081046108 @default.
- W2129501023 cites W2086231230 @default.
- W2129501023 cites W2092896174 @default.
- W2129501023 cites W2325199355 @default.
- W2129501023 doi "https://doi.org/10.1126/science.287.5456.1258" @default.
- W2129501023 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10678831" @default.
- W2129501023 hasPublicationYear "2000" @default.
- W2129501023 type Work @default.
- W2129501023 sameAs 2129501023 @default.
- W2129501023 citedByCount "316" @default.
- W2129501023 countsByYear W21295010232012 @default.
- W2129501023 countsByYear W21295010232013 @default.
- W2129501023 countsByYear W21295010232014 @default.
- W2129501023 countsByYear W21295010232015 @default.
- W2129501023 countsByYear W21295010232016 @default.
- W2129501023 countsByYear W21295010232017 @default.
- W2129501023 countsByYear W21295010232018 @default.
- W2129501023 countsByYear W21295010232019 @default.
- W2129501023 countsByYear W21295010232020 @default.
- W2129501023 countsByYear W21295010232021 @default.
- W2129501023 countsByYear W21295010232022 @default.
- W2129501023 countsByYear W21295010232023 @default.
- W2129501023 crossrefType "journal-article" @default.
- W2129501023 hasAuthorship W2129501023A5003021411 @default.
- W2129501023 hasAuthorship W2129501023A5020887225 @default.
- W2129501023 hasAuthorship W2129501023A5021126434 @default.
- W2129501023 hasAuthorship W2129501023A5021973822 @default.
- W2129501023 hasAuthorship W2129501023A5029014038 @default.
- W2129501023 hasAuthorship W2129501023A5057211368 @default.
- W2129501023 hasAuthorship W2129501023A5059745520 @default.
- W2129501023 hasAuthorship W2129501023A5067360623 @default.
- W2129501023 hasAuthorship W2129501023A5068717107 @default.
- W2129501023 hasAuthorship W2129501023A5069853713 @default.
- W2129501023 hasAuthorship W2129501023A5078855662 @default.
- W2129501023 hasConcept C104317684 @default.
- W2129501023 hasConcept C126322002 @default.
- W2129501023 hasConcept C127716648 @default.
- W2129501023 hasConcept C138885662 @default.
- W2129501023 hasConcept C1491633281 @default.
- W2129501023 hasConcept C194051981 @default.
- W2129501023 hasConcept C202751555 @default.
- W2129501023 hasConcept C203014093 @default.
- W2129501023 hasConcept C2776200302 @default.
- W2129501023 hasConcept C2777075537 @default.
- W2129501023 hasConcept C2778137410 @default.
- W2129501023 hasConcept C2779609443 @default.
- W2129501023 hasConcept C2780252810 @default.
- W2129501023 hasConcept C2780931953 @default.
- W2129501023 hasConcept C2911091166 @default.
- W2129501023 hasConcept C2994427840 @default.
- W2129501023 hasConcept C41895202 @default.
- W2129501023 hasConcept C55493867 @default.
- W2129501023 hasConcept C6045943 @default.
- W2129501023 hasConcept C70883133 @default.
- W2129501023 hasConcept C71867830 @default.
- W2129501023 hasConcept C71924100 @default.
- W2129501023 hasConcept C86803240 @default.
- W2129501023 hasConceptScore W2129501023C104317684 @default.
- W2129501023 hasConceptScore W2129501023C126322002 @default.
- W2129501023 hasConceptScore W2129501023C127716648 @default.
- W2129501023 hasConceptScore W2129501023C138885662 @default.
- W2129501023 hasConceptScore W2129501023C1491633281 @default.
- W2129501023 hasConceptScore W2129501023C194051981 @default.
- W2129501023 hasConceptScore W2129501023C202751555 @default.
- W2129501023 hasConceptScore W2129501023C203014093 @default.
- W2129501023 hasConceptScore W2129501023C2776200302 @default.
- W2129501023 hasConceptScore W2129501023C2777075537 @default.
- W2129501023 hasConceptScore W2129501023C2778137410 @default.
- W2129501023 hasConceptScore W2129501023C2779609443 @default.
- W2129501023 hasConceptScore W2129501023C2780252810 @default.
- W2129501023 hasConceptScore W2129501023C2780931953 @default.