FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2129602016> ?p ?o ?g. }

• W2129602016 endingPage "279" @default.
• W2129602016 startingPage "265" @default.
• W2129602016 abstract "Abstract The recent action of positive selection is expected to influence patterns of intraspecific DNA sequence variation in chromosomal regions linked to the selected locus. These effects include decreased polymorphism, increased linkage disequilibrium, and an increased frequency of derived variants. These effects are all expected to dissipate with distance from the selected locus due to recombination. Therefore, in regions of high recombination, it should be possible to localize a target of selection to a relatively small interval. Previously described patterns of intraspecific variation in three tandemly arranged, testes-expressed genes (janusA, janusB, and ocnus) in Drosophila simulans included all three of these features. Here we expand the original sample and also survey nucleotide polymorphism at three neighboring loci. On the basis of recombination events between derived and ancestral alleles, we localize the target of selection to a 1.5-kb region surrounding janusB. A composite-likelihood-ratio test based on the spatial distribution and frequency of derived polymorphic variants corroborates this result and provides an estimate of the strength of selection. However, the data are difficult to reconcile with the simplest model of positive selection, whereas a new composite-likelihood method suggests that the data are better described by a model in which the selected allele has not yet gone to fixation." @default.
• W2129602016 created "2016-06-24" @default.
• W2129602016 creator A5035799601 @default.
• W2129602016 creator A5038430822 @default.
• W2129602016 creator A5061240448 @default.
• W2129602016 creator A5067272625 @default.
• W2129602016 date "2004-09-01" @default.
• W2129602016 modified "2023-09-27" @default.
• W2129602016 title "Identification of a Locus Under Complex Positive Selection in Drosophila simulans by Haplotype Mapping and Composite-Likelihood Estimation" @default.
• W2129602016 cites W1802808450 @default.
• W2129602016 cites W1848929312 @default.
• W2129602016 cites W1895970757 @default.
• W2129602016 cites W1913866456 @default.
• W2129602016 cites W1928220195 @default.
• W2129602016 cites W1932538605 @default.
• W2129602016 cites W1946694389 @default.
• W2129602016 cites W1947714123 @default.
• W2129602016 cites W1949557888 @default.
• W2129602016 cites W1978224130 @default.
• W2129602016 cites W1982603712 @default.
• W2129602016 cites W1990442358 @default.
• W2129602016 cites W1993351732 @default.
• W2129602016 cites W2000898218 @default.
• W2129602016 cites W2008711748 @default.
• W2129602016 cites W2012944745 @default.
• W2129602016 cites W2014673667 @default.
• W2129602016 cites W2024239836 @default.
• W2129602016 cites W2024745007 @default.
• W2129602016 cites W2041993291 @default.
• W2129602016 cites W2052955546 @default.
• W2129602016 cites W2055543630 @default.
• W2129602016 cites W2071537172 @default.
• W2129602016 cites W2082967637 @default.
• W2129602016 cites W2083365573 @default.
• W2129602016 cites W2087453262 @default.
• W2129602016 cites W2097382368 @default.
• W2129602016 cites W2102234847 @default.
• W2129602016 cites W2102714038 @default.
• W2129602016 cites W2106175530 @default.
• W2129602016 cites W2109183238 @default.
• W2129602016 cites W2109261977 @default.
• W2129602016 cites W2113950360 @default.
• W2129602016 cites W2124653005 @default.
• W2129602016 cites W2124684030 @default.
• W2129602016 cites W2124876671 @default.
• W2129602016 cites W2125726783 @default.
• W2129602016 cites W2127864194 @default.
• W2129602016 cites W2127971017 @default.
• W2129602016 cites W2131825880 @default.
• W2129602016 cites W2132393729 @default.
• W2129602016 cites W2132430202 @default.
• W2129602016 cites W2135588481 @default.
• W2129602016 cites W2135818404 @default.
• W2129602016 cites W2140784970 @default.
• W2129602016 cites W2141652419 @default.
• W2129602016 cites W2141672406 @default.
• W2129602016 cites W2142696575 @default.
• W2129602016 cites W2148556963 @default.
• W2129602016 cites W2149313908 @default.
• W2129602016 cites W2152195140 @default.
• W2129602016 cites W2155294402 @default.
• W2129602016 cites W2155670634 @default.
• W2129602016 cites W2156158902 @default.
• W2129602016 cites W2157149092 @default.
• W2129602016 cites W2161499761 @default.
• W2129602016 cites W2169509509 @default.
• W2129602016 cites W2171207150 @default.
• W2129602016 cites W2171545344 @default.
• W2129602016 cites W2277048347 @default.
• W2129602016 cites W2322144223 @default.
• W2129602016 cites W4251304755 @default.
• W2129602016 cites W4256073354 @default.
• W2129602016 doi "https://doi.org/10.1534/genetics.103.025494" @default.
• W2129602016 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1448127" @default.
• W2129602016 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15454542" @default.
• W2129602016 hasPublicationYear "2004" @default.
• W2129602016 type Work @default.
• W2129602016 sameAs 2129602016 @default.
• W2129602016 citedByCount "44" @default.
• W2129602016 countsByYear W21296020162012 @default.
• W2129602016 countsByYear W21296020162013 @default.
• W2129602016 countsByYear W21296020162015 @default.
• W2129602016 countsByYear W21296020162016 @default.
• W2129602016 countsByYear W21296020162019 @default.
• W2129602016 crossrefType "journal-article" @default.
• W2129602016 hasAuthorship W2129602016A5035799601 @default.
• W2129602016 hasAuthorship W2129602016A5038430822 @default.
• W2129602016 hasAuthorship W2129602016A5061240448 @default.
• W2129602016 hasAuthorship W2129602016A5067272625 @default.
• W2129602016 hasBestOaLocation W21296020161 @default.
• W2129602016 hasConcept C104317684 @default.
• W2129602016 hasConcept C131892835 @default.
• W2129602016 hasConcept C137848329 @default.
• W2129602016 hasConcept C146249460 @default.
• W2129602016 hasConcept C156695909 @default.
• W2129602016 hasConcept C180754005 @default.
• W2129602016 hasConcept C197754878 @default.
• W2129602016 hasConcept C35605836 @default.

• next