FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2129614711> ?p ?o ?g. }

• W2129614711 endingPage "803" @default.
• W2129614711 startingPage "797" @default.
• W2129614711 abstract "Clonal expansion of virus-specific naive T cells during an acute viral infection results in the formation of memory CD8 T cells that provide the host with long-term protective immunity against the pathogen. Memory CD8 T cells display enhanced effector functions compared with their naive precursors, allowing them to respond more rapidly and effectively to antigen re-encounter. The enhanced functions of memory CD8 T cells are mediated by heritable changes in gene regulation. Expression of select transcription factors along with locus-specific epigenetic modifications are coupled to and are essential in the formation of memory-specific gene expression patterns. Here, we will review the changes in gene expression that accompany development of memory CD8 T cells and discuss chromatin modifications as a potential means for heritable propagation of these changes during homeostatic cell division of self-renewing memory CD8 T cells. Also, we will discuss therapies that manipulate heritable gene regulation as a potential mechanism to restore function to non-functional memory CD8 T cells to combat chronic viral infection." @default.
• W2129614711 created "2016-06-24" @default.
• W2129614711 creator A5016808814 @default.
• W2129614711 creator A5054876564 @default.
• W2129614711 creator A5083532018 @default.
• W2129614711 date "2010-08-23" @default.
• W2129614711 modified "2023-09-26" @default.
• W2129614711 title "Making memories that last a lifetime: heritable functions of self-renewing memory CD8 T cells" @default.
• W2129614711 cites W1504303645 @default.
• W2129614711 cites W1523147669 @default.
• W2129614711 cites W1534177339 @default.
• W2129614711 cites W1563453316 @default.
• W2129614711 cites W1603412780 @default.
• W2129614711 cites W1603918837 @default.
• W2129614711 cites W1636607180 @default.
• W2129614711 cites W1970735079 @default.
• W2129614711 cites W1972169216 @default.
• W2129614711 cites W1974842026 @default.
• W2129614711 cites W1974906492 @default.
• W2129614711 cites W1976355501 @default.
• W2129614711 cites W1976785514 @default.
• W2129614711 cites W1981281783 @default.
• W2129614711 cites W1981821080 @default.
• W2129614711 cites W1987337968 @default.
• W2129614711 cites W1993068868 @default.
• W2129614711 cites W1997955204 @default.
• W2129614711 cites W1999140113 @default.
• W2129614711 cites W1999344688 @default.
• W2129614711 cites W2001220448 @default.
• W2129614711 cites W2002129512 @default.
• W2129614711 cites W2002698073 @default.
• W2129614711 cites W2002726823 @default.
• W2129614711 cites W2008261028 @default.
• W2129614711 cites W2008697182 @default.
• W2129614711 cites W2014766736 @default.
• W2129614711 cites W2015688630 @default.
• W2129614711 cites W2016804485 @default.
• W2129614711 cites W2021936785 @default.
• W2129614711 cites W2027132663 @default.
• W2129614711 cites W2029128444 @default.
• W2129614711 cites W2029154862 @default.
• W2129614711 cites W2048157537 @default.
• W2129614711 cites W2048640680 @default.
• W2129614711 cites W2050531099 @default.
• W2129614711 cites W2051001415 @default.
• W2129614711 cites W2054344840 @default.
• W2129614711 cites W2063308082 @default.
• W2129614711 cites W2064656497 @default.
• W2129614711 cites W2069717852 @default.
• W2129614711 cites W2073157961 @default.
• W2129614711 cites W2085140645 @default.
• W2129614711 cites W2085918020 @default.
• W2129614711 cites W2089689396 @default.
• W2129614711 cites W2091623080 @default.
• W2129614711 cites W2092263607 @default.
• W2129614711 cites W2100626956 @default.
• W2129614711 cites W2102264469 @default.
• W2129614711 cites W2102650038 @default.
• W2129614711 cites W2103735500 @default.
• W2129614711 cites W2110459643 @default.
• W2129614711 cites W2118362622 @default.
• W2129614711 cites W2121417064 @default.
• W2129614711 cites W2127910733 @default.
• W2129614711 cites W2130089202 @default.
• W2129614711 cites W2131748930 @default.
• W2129614711 cites W2131881730 @default.
• W2129614711 cites W2133567701 @default.
• W2129614711 cites W2134916334 @default.
• W2129614711 cites W2138323449 @default.
• W2129614711 cites W2141615498 @default.
• W2129614711 cites W2145369044 @default.
• W2129614711 cites W2148224923 @default.
• W2129614711 cites W2149426454 @default.
• W2129614711 cites W2152014155 @default.
• W2129614711 cites W2153769207 @default.
• W2129614711 cites W2153886009 @default.
• W2129614711 cites W2157493506 @default.
• W2129614711 cites W2162543584 @default.
• W2129614711 cites W2163408209 @default.
• W2129614711 cites W2293648610 @default.
• W2129614711 cites W4361772937 @default.
• W2129614711 doi "https://doi.org/10.1093/intimm/dxq437" @default.
• W2129614711 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2946216" @default.
• W2129614711 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20732857" @default.
• W2129614711 hasPublicationYear "2010" @default.
• W2129614711 type Work @default.
• W2129614711 sameAs 2129614711 @default.
• W2129614711 citedByCount "40" @default.
• W2129614711 countsByYear W21296147112012 @default.
• W2129614711 countsByYear W21296147112013 @default.
• W2129614711 countsByYear W21296147112014 @default.
• W2129614711 countsByYear W21296147112015 @default.
• W2129614711 countsByYear W21296147112016 @default.
• W2129614711 countsByYear W21296147112017 @default.
• W2129614711 countsByYear W21296147112018 @default.
• W2129614711 countsByYear W21296147112020 @default.
• W2129614711 countsByYear W21296147112021 @default.
• W2129614711 countsByYear W21296147112022 @default.

• next