FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2129672275> ?p ?o ?g. }

• W2129672275 abstract "Insufficient leukocyte recruitment may be one reason for the high incidence of life-threatening infections in preterm infants. Since the receptor of advanced glycation end products (RAGE) is a known leukocyte adhesion molecule and highly expressed during early development, we asked whether RAGE plays a role for leukocyte recruitment in preterm and term infants. Leukocyte adhesion was analyzed in dynamic flow chamber experiments using isolated leukocytes of cord blood from extremely premature (<30 weeks of gestation), moderately premature (30-35 weeks of gestation) and mature neonates (>35 weeks of gestation) and compared to the results of adults. For fluorescent microscopy leukocytes were labeled with rhodamine 6G. In the respective age groups we also measured the plasma concentration of soluble RAGE (sRAGE) by ELISA and Mac-1 and LFA-1 expression on neutrophils by flow cytometry. The adhesive functions of fetal leukocytes significantly increase with gestational age. In all age groups, leukocyte adhesion was crucially dependent on RAGE. In particular, RAGE was equally effective to mediate leukocyte adhesion when compared to ICAM-1. The plasma levels of sRAGE were high in extremely premature infants and decreased with increasing gestational age. In contrast, expression of β2-Integrins Mac-1 and LFA-1 which are known ligands for RAGE and ICAM-1 did not change during fetal development. We conclude that RAGE is a crucial leukocyte adhesion molecule in both preterm and term infants." @default.
• W2129672275 created "2016-06-24" @default.
• W2129672275 creator A5005661844 @default.
• W2129672275 creator A5018355585 @default.
• W2129672275 creator A5035741224 @default.
• W2129672275 creator A5037732727 @default.
• W2129672275 creator A5039857937 @default.
• W2129672275 creator A5054677191 @default.
• W2129672275 creator A5076050764 @default.
• W2129672275 creator A5086162081 @default.
• W2129672275 date "2014-11-27" @default.
• W2129672275 modified "2023-10-14" @default.
• W2129672275 title "RAGE controls leukocyte adhesion in preterm and term infants" @default.
• W2129672275 cites W1600560134 @default.
• W2129672275 cites W162166184 @default.
• W2129672275 cites W1972921168 @default.
• W2129672275 cites W1981491852 @default.
• W2129672275 cites W1981689863 @default.
• W2129672275 cites W1982947936 @default.
• W2129672275 cites W1983701023 @default.
• W2129672275 cites W1991471550 @default.
• W2129672275 cites W1999652376 @default.
• W2129672275 cites W2000186876 @default.
• W2129672275 cites W2009534517 @default.
• W2129672275 cites W2015837671 @default.
• W2129672275 cites W2018686118 @default.
• W2129672275 cites W2021567384 @default.
• W2129672275 cites W2021627883 @default.
• W2129672275 cites W2021882325 @default.
• W2129672275 cites W2023915714 @default.
• W2129672275 cites W20272483 @default.
• W2129672275 cites W2027819189 @default.
• W2129672275 cites W2035387676 @default.
• W2129672275 cites W2035809865 @default.
• W2129672275 cites W2039398836 @default.
• W2129672275 cites W2045442917 @default.
• W2129672275 cites W2062242135 @default.
• W2129672275 cites W2064027586 @default.
• W2129672275 cites W2068966033 @default.
• W2129672275 cites W2078433449 @default.
• W2129672275 cites W2083419397 @default.
• W2129672275 cites W2086327676 @default.
• W2129672275 cites W2089130340 @default.
• W2129672275 cites W2091280521 @default.
• W2129672275 cites W2102316212 @default.
• W2129672275 cites W2104938297 @default.
• W2129672275 cites W2109202597 @default.
• W2129672275 cites W2109334664 @default.
• W2129672275 cites W2112079611 @default.
• W2129672275 cites W2117783767 @default.
• W2129672275 cites W2123333906 @default.
• W2129672275 cites W2132404990 @default.
• W2129672275 cites W2133205894 @default.
• W2129672275 cites W2141924291 @default.
• W2129672275 cites W2148599633 @default.
• W2129672275 cites W2163464980 @default.
• W2129672275 cites W2167916551 @default.
• W2129672275 cites W2267975722 @default.
• W2129672275 cites W2278111142 @default.
• W2129672275 cites W2331879955 @default.
• W2129672275 cites W2404652029 @default.
• W2129672275 cites W2406384025 @default.
• W2129672275 cites W2412334556 @default.
• W2129672275 cites W2444675328 @default.
• W2129672275 cites W4236240401 @default.
• W2129672275 cites W4245060634 @default.
• W2129672275 doi "https://doi.org/10.1186/s12865-014-0053-0" @default.
• W2129672275 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4256735" @default.
• W2129672275 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25428166" @default.
• W2129672275 hasPublicationYear "2014" @default.
• W2129672275 type Work @default.
• W2129672275 sameAs 2129672275 @default.
• W2129672275 citedByCount "15" @default.
• W2129672275 countsByYear W21296722752013 @default.
• W2129672275 countsByYear W21296722752016 @default.
• W2129672275 countsByYear W21296722752017 @default.
• W2129672275 countsByYear W21296722752018 @default.
• W2129672275 countsByYear W21296722752019 @default.
• W2129672275 countsByYear W21296722752020 @default.
• W2129672275 countsByYear W21296722752021 @default.
• W2129672275 countsByYear W21296722752023 @default.
• W2129672275 crossrefType "journal-article" @default.
• W2129672275 hasAuthorship W2129672275A5005661844 @default.
• W2129672275 hasAuthorship W2129672275A5018355585 @default.
• W2129672275 hasAuthorship W2129672275A5035741224 @default.
• W2129672275 hasAuthorship W2129672275A5037732727 @default.
• W2129672275 hasAuthorship W2129672275A5039857937 @default.
• W2129672275 hasAuthorship W2129672275A5054677191 @default.
• W2129672275 hasAuthorship W2129672275A5076050764 @default.
• W2129672275 hasAuthorship W2129672275A5086162081 @default.
• W2129672275 hasBestOaLocation W21296722751 @default.
• W2129672275 hasConcept C155619193 @default.
• W2129672275 hasConcept C16224149 @default.
• W2129672275 hasConcept C16685009 @default.
• W2129672275 hasConcept C169760540 @default.
• W2129672275 hasConcept C171779818 @default.
• W2129672275 hasConcept C172680121 @default.
• W2129672275 hasConcept C178790620 @default.
• W2129672275 hasConcept C185592680 @default.
• W2129672275 hasConcept C203014093 @default.

• next