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- W2129702378 endingPage "715" @default.
- W2129702378 startingPage "692" @default.
- W2129702378 abstract "A pregnancy rate of approximately 15% per cycle renders the process of human reproduction inefficient. The cycle-dependent expression of molecules involved in the embryo-endometrial dialogue has lead to the identification of a 'window of implantation'. This is the unique temporal and spatial expression of factors that allows the embryo to implant (via signalling, appositioning, attachment and invasion) in a specific time frame of 48 h, 7-10 days after ovulation. Integrin molecules, L-selectin ligands, mucin-1, heparin-binding epidermal growth factor and pinopodes are involved in appositioning and attachment. The embryo produces cytokines and growth factors [interleukins, prostaglandins, vascular endothelial growth factor (VEGF)] and receptors for endometrial signals (leukaemia inhibitory factor receptor, colony stimulating factor receptor, insulin-like growth factors and heparin binding epidermal growth factor receptor). The immune system plays an important role. Immunomodulatory factors such as glycodelin, inhibin and interleukin prevent a graft-versus-host reaction. Angiogenesis controlled by VEGF and prostaglandins is needed for formation of a receptive endometrium and a placenta. Identification of these factors has led to their use as markers of implantation that may identify defects causing subfertility. An ideal marker of implantation is sensitive and specific, and easy to obtain without disturbing implantation. Glycodelin and leukaemia inhibitory factor (serum) and integrins and pinopodes (biopsies) are promising candidates." @default.
- W2129702378 created "2016-06-24" @default.
- W2129702378 creator A5016039667 @default.
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- W2129702378 creator A5040405473 @default.
- W2129702378 creator A5059035543 @default.
- W2129702378 date "2004-01-01" @default.
- W2129702378 modified "2023-10-06" @default.
- W2129702378 title "Human embryo implantation: current knowledge and clinical implications in assisted reproductive technology" @default.
- W2129702378 cites W1451684643 @default.
- W2129702378 cites W1483372572 @default.
- W2129702378 cites W150117591 @default.
- W2129702378 cites W1533158188 @default.
- W2129702378 cites W1537712767 @default.
- W2129702378 cites W1586250986 @default.
- W2129702378 cites W1679229092 @default.
- W2129702378 cites W182589694 @default.
- W2129702378 cites W1858991678 @default.
- W2129702378 cites W1913535692 @default.
- W2129702378 cites W1917321164 @default.
- W2129702378 cites W193754658 @default.
- W2129702378 cites W1949419678 @default.
- W2129702378 cites W1964764413 @default.
- W2129702378 cites W1965498412 @default.
- W2129702378 cites W1966007893 @default.
- W2129702378 cites W1966025834 @default.
- W2129702378 cites W1967348430 @default.
- W2129702378 cites W1967906263 @default.
- W2129702378 cites W1970357508 @default.
- W2129702378 cites W1970398896 @default.
- W2129702378 cites W1971784353 @default.
- W2129702378 cites W1971943219 @default.
- W2129702378 cites W1974456378 @default.
- W2129702378 cites W1976598098 @default.
- W2129702378 cites W1978410153 @default.
- W2129702378 cites W1978677754 @default.
- W2129702378 cites W1980584021 @default.
- W2129702378 cites W1983001210 @default.
- W2129702378 cites W1983705943 @default.
- W2129702378 cites W1983754168 @default.
- W2129702378 cites W1985079327 @default.
- W2129702378 cites W1985145404 @default.
- W2129702378 cites W1985458988 @default.
- W2129702378 cites W1986605550 @default.
- W2129702378 cites W1989730434 @default.
- W2129702378 cites W1990030459 @default.
- W2129702378 cites W1990389515 @default.
- W2129702378 cites W1990754470 @default.
- W2129702378 cites W1990778555 @default.
- W2129702378 cites W1991482386 @default.
- W2129702378 cites W1992160731 @default.
- W2129702378 cites W1995559307 @default.
- W2129702378 cites W1995804923 @default.
- W2129702378 cites W1996007721 @default.
- W2129702378 cites W1998498869 @default.
- W2129702378 cites W1998569665 @default.
- W2129702378 cites W2001738627 @default.
- W2129702378 cites W2002049222 @default.
- W2129702378 cites W2002341416 @default.
- W2129702378 cites W2003415827 @default.
- W2129702378 cites W2003885969 @default.
- W2129702378 cites W2005247421 @default.
- W2129702378 cites W2006556586 @default.
- W2129702378 cites W2007582427 @default.
- W2129702378 cites W2008812115 @default.
- W2129702378 cites W2009856290 @default.
- W2129702378 cites W2010086960 @default.
- W2129702378 cites W2011409004 @default.
- W2129702378 cites W2011647496 @default.
- W2129702378 cites W2011809207 @default.
- W2129702378 cites W2012199238 @default.
- W2129702378 cites W2012293206 @default.
- W2129702378 cites W2012313039 @default.
- W2129702378 cites W2013155203 @default.
- W2129702378 cites W2014797276 @default.
- W2129702378 cites W2015851954 @default.
- W2129702378 cites W2018855387 @default.
- W2129702378 cites W2019689572 @default.
- W2129702378 cites W2020682411 @default.
- W2129702378 cites W2022617452 @default.
- W2129702378 cites W2024149482 @default.
- W2129702378 cites W2025448279 @default.
- W2129702378 cites W2027464280 @default.
- W2129702378 cites W2027737545 @default.
- W2129702378 cites W2028604572 @default.
- W2129702378 cites W2028829895 @default.
- W2129702378 cites W2031399745 @default.
- W2129702378 cites W2031628629 @default.
- W2129702378 cites W2031779604 @default.
- W2129702378 cites W2033526345 @default.
- W2129702378 cites W2035058854 @default.
- W2129702378 cites W2036538992 @default.
- W2129702378 cites W2037535156 @default.
- W2129702378 cites W2037990541 @default.
- W2129702378 cites W2039585575 @default.
- W2129702378 cites W2040875968 @default.
- W2129702378 cites W2041633092 @default.