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• W2129743025 endingPage "135" @default.
• W2129743025 startingPage "130" @default.
• W2129743025 abstract "To explore the time and pattern of recurrence of proximal gastric cancer and estimate the risk factors and prognostic factors for it. Considering these risk factors, postoperative adjuvant therapies and follow-up program can be individualized.The data of 135 recurrence proximal gastric cancer patients were extracted and analyzed.In 135 recurrence patients, the median time to recurrence was 14.0 months, 116 (85.9%) patients had recurrences within 2 years. Loco-regional recurrence was the most prevalent pattern. Hematogenous metastasis was next prevalent pattern in which the liver was the most common organ. Peritoneal recurrence occurred in 32 patients. Five patients recurred in distant lymph nodes. The deeper invasion was associated with higher incidence of hematogenous metastases and peritoneal recurrence. The histological type, depth of invasion, and lymph node metastasis were independent risk factors for overall recurrence. While, negative lymph nodes counts were another independent risk factors for early recurrence. Patients with systemic recurrence and early recurrence patients had poorer prognosis.Total gastrectomy and adequate lymph nodes dissection were rational choice of proximal gastric cancer with deeper invasion. Pathologic predictors of invasion, histological type, lymph nodes metastasis and negative lymph node counts could guide individualized, risk-oriented adjuvant treatment, and follow-up plan." @default.
• W2129743025 created "2016-06-24" @default.
• W2129743025 creator A5006884460 @default.
• W2129743025 creator A5044301848 @default.
• W2129743025 creator A5055859642 @default.
• W2129743025 creator A5068464160 @default.
• W2129743025 creator A5089349047 @default.
• W2129743025 date "2012-09-04" @default.
• W2129743025 modified "2023-10-05" @default.
• W2129743025 title "The pattern and risk factors of recurrence of proximal gastric cancer after curative resection" @default.
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• W2129743025 doi "https://doi.org/10.1002/jso.23252" @default.
• W2129743025 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22949400" @default.
• W2129743025 hasPublicationYear "2012" @default.
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