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- W2129827225 abstract "To investigate whether the production of acetate which occurs after exposure of respiring Saccharomyces cerevisiae cells to excess glucose can be reduced by overproduction of acetyl-CoA synthetase (ACS, EC 6.2.1.1), the ACS1 and ACS2 genes were introduced on multi-copy plasmids. For each isoenzyme, the level in glucose-limited chemostat cultures was increased by 3-6-fold, relative to an isogenic reference strain. However, ACS overproduction did not result in a reduced production of acetate after a glucose pulse (100 mmol l-1) to these cultures. This indicates that a limited capacity of ACS is not the sole cause of acetate accumulation in S. cerevisiae." @default.
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- W2129827225 date "1998-08-01" @default.
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- W2129827225 title "Overproduction of acetyl-coenzyme A synthetase isoenzymes in respiringSaccharomyces cerevisiaecells does not reduce acetate production after exposure to glucose excess" @default.
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- W2129827225 doi "https://doi.org/10.1111/j.1574-6968.1998.tb13121.x" @default.
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