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- W2129850344 abstract "La artritis reumatoide es una enfermedad inflamatoria crónica sistémica que ocasiona una significativa morbilidad y mortalidad. El uso combinado de metotrexato y agentes biológicos dirigidos contra el factor de necrosis tumoral (TNF) ha logrado mejorías significativas en parámetros clínicos, radiográficos y funcionales que no se habían visto previamente y que han revolucionado el objetivo terapéutico de conseguir la remisión en parámetros clínicos, estructurales y funcionales. El próximo objetivo debería ser alcanzar la remisión sin el uso de fármacos biológicos y posteriormente sin medicación. Aunque hay evidencia acerca de la eficacia y la seguridad de los inhibidores del TNF, no la hay acerca de remisión sin el empleo de agentes biológicos ni fármacos modificadores de la enfermedad. Rheumatoid arthritis is a chronic systemic inflammatory disease that causes significant morbidity and mortality. The combined use of methotrexate and biological agents directed against tumor necrosis factor (TNF) has achieved significant improvement in clinical, radiographic and functional parameters not seen previously and has revolutionized the therapeutic goal of achieving remission in clinical, structural and functional parameters. The next goal should be to achieve remission without the use of biological drugs and later without medication. Although there is evidence about the efficacy and safety of TNF inhibitors, there is none on remission without the use of biological agents or disease modifying drugs." @default.
- W2129850344 created "2016-06-24" @default.
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- W2129850344 date "2012-01-01" @default.
- W2129850344 modified "2023-09-25" @default.
- W2129850344 title "¿Se puede suspender la medicación en los pacientes con artritis reumatoide en remisión?" @default.
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- W2129850344 doi "https://doi.org/10.1016/j.reuma.2011.08.003" @default.
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