FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2129865769> ?p ?o ?g. }

• W2129865769 abstract "Vascular disorders have been implicated in the development of cognitive decline and dementia and atherosclerosis is believed to be involved in the development of the most common type of dementia, Alzheimer's disease. Although a low ankle-brachial index (ABI) reflects the presence of atherosclerosis of the arterial walls in the lower extremities and is a good indicator of generalized atherosclerosis, data on cognitive prognosis of patients with a low ABI are limited. This study aimed to investigate the association of the ABI to several grades of cognitive impairment including normal cognition (NC), amnestic mild cognitive impairment (MCI) and Alzheimer's disesase (AD) in the Korean elderly. Five hundred ninety five subjects (NC 100, amnestic MCI 291 and probable AD 204) aged 60 years old and over enrolled in the Dementia and Age-associated Cognitive Decline Clinic of an university hospital and in a service program for the early detection and management of dementia in the community. The ABI was measured as a generalized atherosclerosis. The subjects were divided into 3 groups according to the ABI tertiles and and a multivariate logistic regression analysis was applied to determine the association between the ABI and the grades of cognitive impairment. Measurement included height, weight, body mass index (BMI), blood pressure, serum total cholesterol, LDL cholesterol, triglyceride, hemostatic factors, and presence of cardiovascular diseases. Subjects with NC were significantly younger than those with either of amnestic MCI or probable AD and well educated than those with probable AD. Subjects with NC also was higher in height and lower in body weight, systolic and diastolic blood pressure, serum total cholesterol, LDL cholesterol and various hemostatic factors. When the subjects were divided into 2 groups (NC versus aMCI and AD), after adjusting for confounding factors, the lowest ABI tertile was significantly associated with an increased risk of cognitive impairment such as aMCI and AD. (OR=2.65, 95%CI=1.43–4.95). This cross-sectional study suggests that the ABI may be an independent risk factor for cognitive impairment and useful in identifying older individuals at higher risk of AD and amnestic MCI, a prodromal stage of AD." @default.
• W2129865769 created "2016-06-24" @default.
• W2129865769 creator A5006680872 @default.
• W2129865769 creator A5009560777 @default.
• W2129865769 creator A5011863774 @default.
• W2129865769 creator A5023962924 @default.
• W2129865769 creator A5051618759 @default.
• W2129865769 creator A5070033243 @default.
• W2129865769 creator A5073284312 @default.
• W2129865769 creator A5073307814 @default.
• W2129865769 creator A5073695188 @default.
• W2129865769 creator A5077092088 @default.
• W2129865769 creator A5078175720 @default.
• W2129865769 date "2013-07-01" @default.
• W2129865769 modified "2023-10-16" @default.
• W2129865769 title "P4-069: Association of ankle brachial index among the elderly with normal cognition, amnestic mild cognitive impairment and Alzheimer's disease" @default.
• W2129865769 doi "https://doi.org/10.1016/j.jalz.2013.05.1458" @default.
• W2129865769 hasPublicationYear "2013" @default.
• W2129865769 type Work @default.
• W2129865769 sameAs 2129865769 @default.
• W2129865769 citedByCount "0" @default.
• W2129865769 crossrefType "journal-article" @default.
• W2129865769 hasAuthorship W2129865769A5006680872 @default.
• W2129865769 hasAuthorship W2129865769A5009560777 @default.
• W2129865769 hasAuthorship W2129865769A5011863774 @default.
• W2129865769 hasAuthorship W2129865769A5023962924 @default.
• W2129865769 hasAuthorship W2129865769A5051618759 @default.
• W2129865769 hasAuthorship W2129865769A5070033243 @default.
• W2129865769 hasAuthorship W2129865769A5073284312 @default.
• W2129865769 hasAuthorship W2129865769A5073307814 @default.
• W2129865769 hasAuthorship W2129865769A5073695188 @default.
• W2129865769 hasAuthorship W2129865769A5077092088 @default.
• W2129865769 hasAuthorship W2129865769A5078175720 @default.
• W2129865769 hasBestOaLocation W21298657691 @default.
• W2129865769 hasConcept C118552586 @default.
• W2129865769 hasConcept C126322002 @default.
• W2129865769 hasConcept C151956035 @default.
• W2129865769 hasConcept C164705383 @default.
• W2129865769 hasConcept C169900460 @default.
• W2129865769 hasConcept C1862650 @default.
• W2129865769 hasConcept C2779134260 @default.
• W2129865769 hasConcept C2779483572 @default.
• W2129865769 hasConcept C2780221984 @default.
• W2129865769 hasConcept C2984863031 @default.
• W2129865769 hasConcept C2984915365 @default.
• W2129865769 hasConcept C502032728 @default.
• W2129865769 hasConcept C71924100 @default.
• W2129865769 hasConcept C84393581 @default.
• W2129865769 hasConceptScore W2129865769C118552586 @default.
• W2129865769 hasConceptScore W2129865769C126322002 @default.
• W2129865769 hasConceptScore W2129865769C151956035 @default.
• W2129865769 hasConceptScore W2129865769C164705383 @default.
• W2129865769 hasConceptScore W2129865769C169900460 @default.
• W2129865769 hasConceptScore W2129865769C1862650 @default.
• W2129865769 hasConceptScore W2129865769C2779134260 @default.
• W2129865769 hasConceptScore W2129865769C2779483572 @default.
• W2129865769 hasConceptScore W2129865769C2780221984 @default.
• W2129865769 hasConceptScore W2129865769C2984863031 @default.
• W2129865769 hasConceptScore W2129865769C2984915365 @default.
• W2129865769 hasConceptScore W2129865769C502032728 @default.
• W2129865769 hasConceptScore W2129865769C71924100 @default.
• W2129865769 hasConceptScore W2129865769C84393581 @default.
• W2129865769 hasIssue "4S_Part_18" @default.
• W2129865769 hasLocation W21298657691 @default.
• W2129865769 hasOpenAccess W2129865769 @default.
• W2129865769 hasPrimaryLocation W21298657691 @default.
• W2129865769 hasRelatedWork W1552932904 @default.
• W2129865769 hasRelatedWork W182016951 @default.
• W2129865769 hasRelatedWork W2005941035 @default.
• W2129865769 hasRelatedWork W2064114605 @default.
• W2129865769 hasRelatedWork W2070165017 @default.
• W2129865769 hasRelatedWork W2077992747 @default.
• W2129865769 hasRelatedWork W2561267217 @default.
• W2129865769 hasRelatedWork W2963614523 @default.
• W2129865769 hasRelatedWork W2992906473 @default.
• W2129865769 hasRelatedWork W4312389194 @default.
• W2129865769 hasVolume "9" @default.
• W2129865769 isParatext "false" @default.
• W2129865769 isRetracted "false" @default.
• W2129865769 magId "2129865769" @default.
• W2129865769 workType "article" @default.