FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2129873928> ?p ?o ?g. }

• W2129873928 endingPage "396" @default.
• W2129873928 startingPage "391" @default.
• W2129873928 abstract "In glioblastoma-derived cell lines, PTEN does not significantly alter apoptotic sensitivity or cause complete inhibition of DNA synthesis. However, in these cell lines PTEN regulates hypoxia- and IGF-1-induced angiogenic gene expression by regulating Akt activation of HIF-1 activity. Restoration of wild-type PTEN to glioblastoma cell lines lacking functional PTEN ablates hypoxia and IGF-1 induction of HIF-1-regulated genes. In addition, Akt activation leads to HIF-1α stabilization, whereas PTEN attenuates hypoxia-mediated HIF-1α stabilization. We propose that loss of PTEN during malignant progression contributes to tumor expansion through the deregulation of Akt activity and HIF-1-regulated gene expression." @default.
• W2129873928 created "2016-06-24" @default.
• W2129873928 creator A5000205436 @default.
• W2129873928 creator A5022982252 @default.
• W2129873928 creator A5038524862 @default.
• W2129873928 creator A5040158405 @default.
• W2129873928 creator A5044213465 @default.
• W2129873928 creator A5045581960 @default.
• W2129873928 creator A5056873120 @default.
• W2129873928 creator A5062130793 @default.
• W2129873928 creator A5071185138 @default.
• W2129873928 creator A5080172191 @default.
• W2129873928 creator A5082108617 @default.
• W2129873928 creator A5085032736 @default.
• W2129873928 date "2000-02-15" @default.
• W2129873928 modified "2023-10-10" @default.
• W2129873928 title "Loss of <i>PTEN</i> facilitates HIF-1-mediated gene expression" @default.
• W2129873928 cites W1489145507 @default.
• W2129873928 cites W1567768016 @default.
• W2129873928 cites W1587286343 @default.
• W2129873928 cites W1625966995 @default.
• W2129873928 cites W1637251086 @default.
• W2129873928 cites W1749022239 @default.
• W2129873928 cites W177380973 @default.
• W2129873928 cites W1976399432 @default.
• W2129873928 cites W1982479809 @default.
• W2129873928 cites W1984418041 @default.
• W2129873928 cites W1987970382 @default.
• W2129873928 cites W1993163893 @default.
• W2129873928 cites W1998038367 @default.
• W2129873928 cites W2019759067 @default.
• W2129873928 cites W2028796640 @default.
• W2129873928 cites W2028999918 @default.
• W2129873928 cites W2029219396 @default.
• W2129873928 cites W2033783187 @default.
• W2129873928 cites W2053265248 @default.
• W2129873928 cites W2059692699 @default.
• W2129873928 cites W2068345721 @default.
• W2129873928 cites W2068427129 @default.
• W2129873928 cites W2071686558 @default.
• W2129873928 cites W2073292880 @default.
• W2129873928 cites W2077673188 @default.
• W2129873928 cites W2087841059 @default.
• W2129873928 cites W2090627731 @default.
• W2129873928 cites W2097767970 @default.
• W2129873928 cites W2102369096 @default.
• W2129873928 cites W2108958930 @default.
• W2129873928 cites W2109492293 @default.
• W2129873928 cites W2113255254 @default.
• W2129873928 cites W2118271123 @default.
• W2129873928 cites W2137035181 @default.
• W2129873928 cites W2150233389 @default.
• W2129873928 cites W2156299289 @default.
• W2129873928 cites W2161810908 @default.
• W2129873928 cites W4243559800 @default.
• W2129873928 doi "https://doi.org/10.1101/gad.14.4.391" @default.
• W2129873928 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/316386" @default.
• W2129873928 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10691731" @default.
• W2129873928 hasPublicationYear "2000" @default.
• W2129873928 type Work @default.
• W2129873928 sameAs 2129873928 @default.
• W2129873928 citedByCount "703" @default.
• W2129873928 countsByYear W21298739282012 @default.
• W2129873928 countsByYear W21298739282013 @default.
• W2129873928 countsByYear W21298739282014 @default.
• W2129873928 countsByYear W21298739282015 @default.
• W2129873928 countsByYear W21298739282016 @default.
• W2129873928 countsByYear W21298739282017 @default.
• W2129873928 countsByYear W21298739282018 @default.
• W2129873928 countsByYear W21298739282019 @default.
• W2129873928 countsByYear W21298739282020 @default.
• W2129873928 countsByYear W21298739282021 @default.
• W2129873928 countsByYear W21298739282022 @default.
• W2129873928 countsByYear W21298739282023 @default.
• W2129873928 crossrefType "journal-article" @default.
• W2129873928 hasAuthorship W2129873928A5000205436 @default.
• W2129873928 hasAuthorship W2129873928A5022982252 @default.
• W2129873928 hasAuthorship W2129873928A5038524862 @default.
• W2129873928 hasAuthorship W2129873928A5040158405 @default.
• W2129873928 hasAuthorship W2129873928A5044213465 @default.
• W2129873928 hasAuthorship W2129873928A5045581960 @default.
• W2129873928 hasAuthorship W2129873928A5056873120 @default.
• W2129873928 hasAuthorship W2129873928A5062130793 @default.
• W2129873928 hasAuthorship W2129873928A5071185138 @default.
• W2129873928 hasAuthorship W2129873928A5080172191 @default.
• W2129873928 hasAuthorship W2129873928A5082108617 @default.
• W2129873928 hasAuthorship W2129873928A5085032736 @default.
• W2129873928 hasBestOaLocation W21298739281 @default.
• W2129873928 hasConcept C104317684 @default.
• W2129873928 hasConcept C150194340 @default.
• W2129873928 hasConcept C165864922 @default.
• W2129873928 hasConcept C178790620 @default.
• W2129873928 hasConcept C185592680 @default.
• W2129873928 hasConcept C190283241 @default.
• W2129873928 hasConcept C2777609662 @default.
• W2129873928 hasConcept C502942594 @default.
• W2129873928 hasConcept C540031477 @default.
• W2129873928 hasConcept C54355233 @default.

• next