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- W2129901401 abstract "The major antiasthma drugs currently are prescribed most often in aerosol form, with the use of a variety of inhaled-drug delivery devices. The 20th century has seen the evolution of ever more sophisticated aerosol delivery devices from the crude, medicated mist generators of questionable efficacy developed in the 19th century, to small-volume nebulizers, to the latest generation of metered-dose inhalers (MDIs) and dry-powder inhalers (DPIs).1 It is hoped that further refinements in these devices will occur in the 21st century to make aerosol drug delivery even more efficient and convenient, as well as environmentally friendly. MDIs are currently the most widely used aerosol delivery devices. Over the last two decades, auxilliary devices for MDIs have been developed, such as spacers or aerosol holding chambers, to overcome problems associated with press-andbreathe MDI use. In addition, a growing interest has emerged in microelectronic monitoring devices to help physicians and patients monitor their own inhaler use, to assess and improve compliance, and, at least with one device, to optimize drug delivery from MDIs. The purpose of this review is to provide a broad overview of both current and experimental devices for use in asthma and a brief discussion of what improvements are needed in such devices as we enter the new century." @default.
- W2129901401 created "2016-06-24" @default.
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- W2129901401 date "1998-02-01" @default.
- W2129901401 modified "2023-09-27" @default.
- W2129901401 title "New devices for asthma" @default.
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- W2129901401 doi "https://doi.org/10.1016/s0091-6749(98)70233-7" @default.
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