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- W2129969680 abstract "Fibulin-5 plays an important role in elastic fibre formation in vivo. We have investigated the molecular interactions between fibulin-5 and components of fibrillin-rich microfibrils which form a template for elastin. Fibulin-5 interacted in a dose-dependent manner with a fibrillin-1 N-terminal sequence and with tropoelastin, but not with MAGP-1 (microfibril-associated glycoprotein-1) or decorin. Fibulin-5 did not inhibit interactions between fibrillin-1 N- and C-terminal fragments, or fibrillin-1 interactions with tropoelastin. Fibulin-5 may provide a link between tropoelastin and microfibrils in the pericellular space during elastic fibre assembly." @default.
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- W2129969680 date "2005-05-10" @default.
- W2129969680 modified "2023-09-30" @default.
- W2129969680 title "Fibulin-5 interacts with fibrillin-1 molecules and microfibrils" @default.
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- W2129969680 doi "https://doi.org/10.1042/bj20050368" @default.
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