FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2129992678> ?p ?o ?g. }

• W2129992678 endingPage "367" @default.
• W2129992678 startingPage "355" @default.
• W2129992678 abstract "Small cell lung cancer accounts for approximately 15% of bronchogenic carcinomas. It is the cancer most commonly associated with various paraneoplastic syndromes, including the syndrome of inappropriate antidiuretic hormone secretion, paraneoplastic cerebellar degeneration, and Lambert-Eaton myasthenic syndrome. Because of the high propensity of small cell lung cancer to metastasize early, surgery has a limited role as primary therapy. Although the disease is highly sensitive to chemotherapy and radiation, cure is difficult to achieve. The combination of platinum and etoposide is the accepted standard chemotherapeutic regimen. It is also the accepted standard therapy in combination with thoracic radiotherapy (TRT) for limited-stage disease. Adding TRT increases absolute survival by approximately 5% over chemotherapy alone. Thoracic radiotherapy administered concurrently with chemotherapy is more efficacious than sequential therapy. Furthermore, the survival benefit is greater if TRT is given early rather than late in the course of chemotherapy. Regardless of disease stage, no relevant survival benefit results from increased chemotherapy dose intensity or dose density, altered mode of administration (eg, alternating or sequential administration) of various chemotherapeutic agents, or maintenance chemotherapy. Prophylactic cranial radiation prevents central nervous system recurrence and can improve survival. In Japan and some other Asian countries, the combination of irinotecan and cisplatin is the standard chemotherapeutic regimen. Clinical trials using thalidomide, gefitinib, imatinib, temsirolimus, and farnesyltransferase inhibitors have not shown clinical benefit. Other novel agents such as bevacizumab have shown promising early results and are being evaluated in larger trials." @default.
• W2129992678 created "2016-06-24" @default.
• W2129992678 creator A5013824370 @default.
• W2129992678 creator A5025646273 @default.
• W2129992678 creator A5041114807 @default.
• W2129992678 date "2008-03-01" @default.
• W2129992678 modified "2023-10-16" @default.
• W2129992678 title "Small Cell Lung Cancer" @default.
• W2129992678 cites W104685179 @default.
• W2129992678 cites W1489284756 @default.
• W2129992678 cites W1495781375 @default.
• W2129992678 cites W1839348318 @default.
• W2129992678 cites W1884032213 @default.
• W2129992678 cites W1898381946 @default.
• W2129992678 cites W1898563448 @default.
• W2129992678 cites W1903188031 @default.
• W2129992678 cites W1905406155 @default.
• W2129992678 cites W1907795058 @default.
• W2129992678 cites W1918962731 @default.
• W2129992678 cites W1932169383 @default.
• W2129992678 cites W1934533231 @default.
• W2129992678 cites W1961129053 @default.
• W2129992678 cites W1961171505 @default.
• W2129992678 cites W1966823692 @default.
• W2129992678 cites W1971382968 @default.
• W2129992678 cites W1971501057 @default.
• W2129992678 cites W1973510243 @default.
• W2129992678 cites W1973865448 @default.
• W2129992678 cites W1979045387 @default.
• W2129992678 cites W1984015441 @default.
• W2129992678 cites W1985147506 @default.
• W2129992678 cites W1987981667 @default.
• W2129992678 cites W1988939419 @default.
• W2129992678 cites W1989452576 @default.
• W2129992678 cites W1990674638 @default.
• W2129992678 cites W1992971010 @default.
• W2129992678 cites W1994027559 @default.
• W2129992678 cites W1996661703 @default.
• W2129992678 cites W1997569032 @default.
• W2129992678 cites W2003322206 @default.
• W2129992678 cites W2003415418 @default.
• W2129992678 cites W2004706142 @default.
• W2129992678 cites W2031263930 @default.
• W2129992678 cites W203615578 @default.
• W2129992678 cites W2038051729 @default.
• W2129992678 cites W2047047219 @default.
• W2129992678 cites W2053301922 @default.
• W2129992678 cites W2057580337 @default.
• W2129992678 cites W2058237771 @default.
• W2129992678 cites W2059422367 @default.
• W2129992678 cites W2062410878 @default.
• W2129992678 cites W2067010063 @default.
• W2129992678 cites W2073683299 @default.
• W2129992678 cites W2073700431 @default.
• W2129992678 cites W2077372889 @default.
• W2129992678 cites W2079399000 @default.
• W2129992678 cites W2081860177 @default.
• W2129992678 cites W2085419794 @default.
• W2129992678 cites W2085757096 @default.
• W2129992678 cites W2089993835 @default.
• W2129992678 cites W2090913926 @default.
• W2129992678 cites W2091109753 @default.
• W2129992678 cites W2094953852 @default.
• W2129992678 cites W2094991315 @default.
• W2129992678 cites W2101096093 @default.
• W2129992678 cites W2104380111 @default.
• W2129992678 cites W2105527005 @default.
• W2129992678 cites W2106567289 @default.
• W2129992678 cites W2108348820 @default.
• W2129992678 cites W2110530327 @default.
• W2129992678 cites W2112226419 @default.
• W2129992678 cites W2115465348 @default.
• W2129992678 cites W2116531093 @default.
• W2129992678 cites W211855203 @default.
• W2129992678 cites W2129216844 @default.
• W2129992678 cites W2129638180 @default.
• W2129992678 cites W2131664752 @default.
• W2129992678 cites W2131681882 @default.
• W2129992678 cites W2133495180 @default.
• W2129992678 cites W2138683149 @default.
• W2129992678 cites W2139238985 @default.
• W2129992678 cites W2142858201 @default.
• W2129992678 cites W2147352197 @default.
• W2129992678 cites W2148064743 @default.
• W2129992678 cites W2150878803 @default.
• W2129992678 cites W2153563691 @default.
• W2129992678 cites W2153883696 @default.
• W2129992678 cites W2156307964 @default.
• W2129992678 cites W2160012348 @default.
• W2129992678 cites W2161125717 @default.
• W2129992678 cites W2163530272 @default.
• W2129992678 cites W2164306710 @default.
• W2129992678 cites W2165132221 @default.
• W2129992678 cites W2165701939 @default.
• W2129992678 cites W2168585061 @default.
• W2129992678 cites W2169999184 @default.
• W2129992678 cites W2182825613 @default.
• W2129992678 cites W2265126036 @default.

• next