FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2130032935> ?p ?o ?g. }

• W2130032935 endingPage "503" @default.
• W2130032935 startingPage "498" @default.
• W2130032935 abstract "Aims To investigate clinicopathological significance and prognostic implications of EphA3, CD133 and Ki-67 expression in colorectal cancer. Methods EphA3, CD133 and Ki-67 expression was assessed in 201 cases of paraffin-embedded colorectal carcinoma and 60 cases of distal normal mucosal tissue by immunohistochemistry. Medical records were reviewed and clinicopathological analysis was performed. The differential expression of EphA3 and CD133 protein was detected in 20 cases of fresh resected colorectal carcinoma and 20 cases of matched normal mucosal tissue adjacent to the carcinoma by western blot. Results The expression of EphA3 and CD133 in carcinoma was significantly higher than that in normal mucosal tissue (p=0.008; p=0.004). EphA3 and CD133 were positively correlated with tumour size (p=0.029; p=0.017), histological grade (all p=0.001), infiltrative depth (all p=0.00), lymph node metastasis (all p=0.00), distant metastasis (p=0.017; p=0.030) and TNM stage (all p=0.001). Patients with high expression of EphA3 and CD133 had the lowest survival (all p=0.001) (median survival time of EphA3 positive and negative cases: 34.0 and 72.0 months; median survival time of CD133 positive and negative cases: 34.0 and 77.0 months). Multivariate survival analysis showed that EphA3 and CD133 expression was correlated significantly with shortened survival in patients with colorectal cancer (Cox regression: p=0.001, HR=4.722, 95% CI 2.667 to 8.361; p=0.001, HR=5.224, 95% CI 2.622 to 10.405). EphA3, CD133 and Ki-67 expression in colorectal cancer had positive correlations with each other (all p=0.001). Conclusions EphA3 and CD133 may play an important role in the development and progression of tumours, and thus become useful indicators for clinical assessment of tumour biological behaviour and prognosis in patients with colorectal carcinoma." @default.
• W2130032935 created "2016-06-24" @default.
• W2130032935 creator A5019371142 @default.
• W2130032935 creator A5032679283 @default.
• W2130032935 date "2011-03-17" @default.
• W2130032935 modified "2023-10-16" @default.
• W2130032935 title "Clinicopathological significance and prognostic value of EphA3 and CD133 expression in colorectal carcinoma" @default.
• W2130032935 cites W133253872 @default.
• W2130032935 cites W1556791620 @default.
• W2130032935 cites W1559752086 @default.
• W2130032935 cites W1937853139 @default.
• W2130032935 cites W1978734504 @default.
• W2130032935 cites W1983172551 @default.
• W2130032935 cites W1984645684 @default.
• W2130032935 cites W1987031126 @default.
• W2130032935 cites W2001404876 @default.
• W2130032935 cites W2001544973 @default.
• W2130032935 cites W2009671993 @default.
• W2130032935 cites W2010397777 @default.
• W2130032935 cites W2019893869 @default.
• W2130032935 cites W2019950666 @default.
• W2130032935 cites W2023427658 @default.
• W2130032935 cites W2025338468 @default.
• W2130032935 cites W2029231546 @default.
• W2130032935 cites W2030205108 @default.
• W2130032935 cites W2035008060 @default.
• W2130032935 cites W2035833877 @default.
• W2130032935 cites W2037330590 @default.
• W2130032935 cites W2039169692 @default.
• W2130032935 cites W2049380625 @default.
• W2130032935 cites W2051055358 @default.
• W2130032935 cites W2056829678 @default.
• W2130032935 cites W2061822602 @default.
• W2130032935 cites W2062586342 @default.
• W2130032935 cites W2083998563 @default.
• W2130032935 cites W2088346679 @default.
• W2130032935 cites W2102249975 @default.
• W2130032935 cites W2105283525 @default.
• W2130032935 cites W2121695889 @default.
• W2130032935 cites W2129444165 @default.
• W2130032935 cites W2133538214 @default.
• W2130032935 cites W2159082261 @default.
• W2130032935 cites W2981558981 @default.
• W2130032935 doi "https://doi.org/10.1136/jcp.2010.087213" @default.
• W2130032935 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21415057" @default.
• W2130032935 hasPublicationYear "2011" @default.
• W2130032935 type Work @default.
• W2130032935 sameAs 2130032935 @default.
• W2130032935 citedByCount "58" @default.
• W2130032935 countsByYear W21300329352012 @default.
• W2130032935 countsByYear W21300329352013 @default.
• W2130032935 countsByYear W21300329352014 @default.
• W2130032935 countsByYear W21300329352015 @default.
• W2130032935 countsByYear W21300329352016 @default.
• W2130032935 countsByYear W21300329352017 @default.
• W2130032935 countsByYear W21300329352018 @default.
• W2130032935 countsByYear W21300329352019 @default.
• W2130032935 countsByYear W21300329352020 @default.
• W2130032935 countsByYear W21300329352021 @default.
• W2130032935 countsByYear W21300329352022 @default.
• W2130032935 countsByYear W21300329352023 @default.
• W2130032935 crossrefType "journal-article" @default.
• W2130032935 hasAuthorship W2130032935A5019371142 @default.
• W2130032935 hasAuthorship W2130032935A5032679283 @default.
• W2130032935 hasConcept C10515644 @default.
• W2130032935 hasConcept C121608353 @default.
• W2130032935 hasConcept C126322002 @default.
• W2130032935 hasConcept C142724271 @default.
• W2130032935 hasConcept C143998085 @default.
• W2130032935 hasConcept C146357865 @default.
• W2130032935 hasConcept C151730666 @default.
• W2130032935 hasConcept C193270364 @default.
• W2130032935 hasConcept C204232928 @default.
• W2130032935 hasConcept C2777546739 @default.
• W2130032935 hasConcept C2779013556 @default.
• W2130032935 hasConcept C50382708 @default.
• W2130032935 hasConcept C526805850 @default.
• W2130032935 hasConcept C71924100 @default.
• W2130032935 hasConcept C86803240 @default.
• W2130032935 hasConcept C90924648 @default.
• W2130032935 hasConceptScore W2130032935C10515644 @default.
• W2130032935 hasConceptScore W2130032935C121608353 @default.
• W2130032935 hasConceptScore W2130032935C126322002 @default.
• W2130032935 hasConceptScore W2130032935C142724271 @default.
• W2130032935 hasConceptScore W2130032935C143998085 @default.
• W2130032935 hasConceptScore W2130032935C146357865 @default.
• W2130032935 hasConceptScore W2130032935C151730666 @default.
• W2130032935 hasConceptScore W2130032935C193270364 @default.
• W2130032935 hasConceptScore W2130032935C204232928 @default.
• W2130032935 hasConceptScore W2130032935C2777546739 @default.
• W2130032935 hasConceptScore W2130032935C2779013556 @default.
• W2130032935 hasConceptScore W2130032935C50382708 @default.
• W2130032935 hasConceptScore W2130032935C526805850 @default.
• W2130032935 hasConceptScore W2130032935C71924100 @default.
• W2130032935 hasConceptScore W2130032935C86803240 @default.
• W2130032935 hasConceptScore W2130032935C90924648 @default.
• W2130032935 hasIssue "6" @default.
• W2130032935 hasLocation W21300329351 @default.

• next