FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2130096583> ?p ?o ?g. }

• W2130096583 endingPage "7383" @default.
• W2130096583 startingPage "7375" @default.
• W2130096583 abstract "Nucleocytoplasmic transport of viral ribonucleoproteins (vRNPs) is an essential aspect of the replication cycle for influenza A, B, and C viruses. These viruses replicate and transcribe their genomes in the nuclei of infected cells. During the late stages of infection, vRNPs must be exported from the nucleus to the cytoplasm prior to transport to viral assembly sites on the cellular plasma membrane. Previously, we demonstrated that the influenza A virus nuclear export protein (NEP, formerly referred to as the NS2 protein) mediates the export of vRNPs. In this report, we suggest that for influenza B and C viruses the nuclear export function is also performed by the orthologous NEP proteins (formerly referred to as the NS2 protein). The influenza virus B and C NEP proteins interact in the yeast two-hybrid assay with a subset of nucleoporins and with the Crm1 nuclear export factor and can functionally replace the effector domain from the human immunodeficiency virus type 1 Rev protein. We established a plasmid transfection system for the generation of virus-like particles (VLPs) in which a functional viral RNA-like chloramphenicol acetyltransferase (CAT) gene is delivered to a new cell. VLPs generated in the absence of the influenza B virus NEP protein were unable to transfer the viral RNA-like CAT gene to a new cell. From these data, we suggest that the nuclear export of the influenza B and C vRNPs are mediated through interaction between NEP proteins and the cellular nucleocytoplasmic export machinery." @default.
• W2130096583 created "2016-06-24" @default.
• W2130096583 creator A5002023063 @default.
• W2130096583 creator A5004404612 @default.
• W2130096583 creator A5009078209 @default.
• W2130096583 creator A5011821997 @default.
• W2130096583 creator A5025223877 @default.
• W2130096583 creator A5035050904 @default.
• W2130096583 date "2001-08-15" @default.
• W2130096583 modified "2023-10-18" @default.
• W2130096583 title "Influenza B and C Virus NEP (NS2) Proteins Possess Nuclear Export Activities" @default.
• W2130096583 cites W1484393797 @default.
• W2130096583 cites W1551446447 @default.
• W2130096583 cites W1562998360 @default.
• W2130096583 cites W1577035872 @default.
• W2130096583 cites W1760236457 @default.
• W2130096583 cites W1915841854 @default.
• W2130096583 cites W1944956309 @default.
• W2130096583 cites W1964400951 @default.
• W2130096583 cites W1964916693 @default.
• W2130096583 cites W1966895511 @default.
• W2130096583 cites W1969900938 @default.
• W2130096583 cites W1973052124 @default.
• W2130096583 cites W1977013948 @default.
• W2130096583 cites W1979585903 @default.
• W2130096583 cites W1993595529 @default.
• W2130096583 cites W1996945369 @default.
• W2130096583 cites W2004004385 @default.
• W2130096583 cites W2008922773 @default.
• W2130096583 cites W2012718799 @default.
• W2130096583 cites W2015394327 @default.
• W2130096583 cites W2015984055 @default.
• W2130096583 cites W2022546848 @default.
• W2130096583 cites W2024251630 @default.
• W2130096583 cites W2024313766 @default.
• W2130096583 cites W2033005386 @default.
• W2130096583 cites W2034606699 @default.
• W2130096583 cites W2046182783 @default.
• W2130096583 cites W2048162805 @default.
• W2130096583 cites W2062364477 @default.
• W2130096583 cites W2069971894 @default.
• W2130096583 cites W2071993841 @default.
• W2130096583 cites W2076938612 @default.
• W2130096583 cites W2086215878 @default.
• W2130096583 cites W2091621138 @default.
• W2130096583 cites W2103287127 @default.
• W2130096583 cites W2103375345 @default.
• W2130096583 cites W2108036827 @default.
• W2130096583 cites W2108270951 @default.
• W2130096583 cites W2109324124 @default.
• W2130096583 cites W2110789340 @default.
• W2130096583 cites W2118216256 @default.
• W2130096583 cites W2121348641 @default.
• W2130096583 cites W2122806729 @default.
• W2130096583 cites W2126052872 @default.
• W2130096583 cites W2126182028 @default.
• W2130096583 cites W2127919461 @default.
• W2130096583 cites W2135038732 @default.
• W2130096583 cites W2135751163 @default.
• W2130096583 cites W2140555147 @default.
• W2130096583 cites W2142331338 @default.
• W2130096583 cites W2143866572 @default.
• W2130096583 cites W2146389912 @default.
• W2130096583 cites W2149134545 @default.
• W2130096583 cites W2150087939 @default.
• W2130096583 cites W2157469282 @default.
• W2130096583 cites W2158374311 @default.
• W2130096583 cites W2171258458 @default.
• W2130096583 cites W2171391835 @default.
• W2130096583 cites W2333689051 @default.
• W2130096583 cites W4240631677 @default.
• W2130096583 doi "https://doi.org/10.1128/jvi.75.16.7375-7383.2001" @default.
• W2130096583 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/114972" @default.
• W2130096583 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11462009" @default.
• W2130096583 hasPublicationYear "2001" @default.
• W2130096583 type Work @default.
• W2130096583 sameAs 2130096583 @default.
• W2130096583 citedByCount "58" @default.
• W2130096583 countsByYear W21300965832012 @default.
• W2130096583 countsByYear W21300965832013 @default.
• W2130096583 countsByYear W21300965832014 @default.
• W2130096583 countsByYear W21300965832016 @default.
• W2130096583 countsByYear W21300965832017 @default.
• W2130096583 countsByYear W21300965832018 @default.
• W2130096583 countsByYear W21300965832019 @default.
• W2130096583 countsByYear W21300965832020 @default.
• W2130096583 countsByYear W21300965832021 @default.
• W2130096583 countsByYear W21300965832023 @default.
• W2130096583 crossrefType "journal-article" @default.
• W2130096583 hasAuthorship W2130096583A5002023063 @default.
• W2130096583 hasAuthorship W2130096583A5004404612 @default.
• W2130096583 hasAuthorship W2130096583A5009078209 @default.
• W2130096583 hasAuthorship W2130096583A5011821997 @default.
• W2130096583 hasAuthorship W2130096583A5025223877 @default.
• W2130096583 hasAuthorship W2130096583A5035050904 @default.
• W2130096583 hasBestOaLocation W21300965831 @default.
• W2130096583 hasConcept C104317684 @default.
• W2130096583 hasConcept C140704245 @default.

• next