FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2130101103> ?p ?o ?g. }

• W2130101103 endingPage "186" @default.
• W2130101103 startingPage "180" @default.
• W2130101103 abstract "Ziziphora tenuior L. known as Kakuti in Persian, is used in traditional medicine for fever, dysentery, uterus infection and as an analgesic. It is used also in the treatment of gastrointestinal disorders as carminative, or remedy of diarrhea or nausea. Major components of plant essential oil including pulegone, isomenthone, thymol, menthone, and piperitone are suggested to be responsible for the mentioned medicinal properties.In the present study, a normal high performance liquid chromatography (HPLC)/photodiode array validated method for quantification of isomenthone, one of the major constituents of Ziziphora, was established for the first time with a simple, rapid and accurate method.HPLC analysis was done on a Waters system, equipped with 515 HPLC pump and waters 2996 photodiode array detector. The column was a Nova-Pak Silica (3.9 × 150 mm), and Empower software was used for the determination of the compounds and processing the data. The method was validated according to USP 32 requirements.A SELECTIVE METHOD FOR THE RESOLUTION OF ISOMENTHONE FROM TWO NEAREST PEAKS, THYMOL, AND CARVACROL WAS OBTAINED WITH GRADIENT SYSTEM OF HEXANE (A), AND HEXANE: ethyl acetate (9:1) (B), starting with A: B (100:0) for 2 minutes, then 0-20% B in 5 minutes, A:B (80:20) for 5 minutes, then 20-30% B in 3 minutes, 30-100% B for 5 minutes, A:B (0:100) for 4 minutes following with equilibrating for 10 minutes. The flow rate was 1 mL/min at 22˚C and the injection volume for the standards and the samples was 20 μL. The retention time for isomenthone was found to be 7.45 minutes. The regression equation was y = 143235x - 2433 with the correlation co-factor R(2) = 0.9992 and the percent recovery of 65.4 ± 3.85%. The sample obtained from 5 g of Z. teniour dried powder in 6 mL extract was standardized to contain 1.14 ± 0.030 μL/mL isomenthone which is equivalent to % 1.37 μL/g of the dried powdered plant. Limit of detection (LOD) and Limit of Quantification (LOQ) were 0.037, and 0.122 µL/mL determined by using the formula based on the signal to noise ratio.Due to this fact that plant extracts may cause irreversible damages to the capillary GC columns, using validated HPLC method for the analysis of these compounds in cruse plant extracts is recommended." @default.
• W2130101103 created "2016-06-24" @default.
• W2130101103 creator A5008097963 @default.
• W2130101103 creator A5031537672 @default.
• W2130101103 creator A5031715817 @default.
• W2130101103 creator A5052484286 @default.
• W2130101103 date "2013-11-02" @default.
• W2130101103 modified "2023-09-26" @default.
• W2130101103 title "Development of a Validated HPLC/Photodiode Array Method for the Determination of Isomenthone in the Aerial Parts of Ziziphora tenuior L." @default.
• W2130101103 cites W1978363760 @default.
• W2130101103 cites W1985341465 @default.
• W2130101103 cites W1991467330 @default.
• W2130101103 cites W2025510848 @default.
• W2130101103 cites W2067947761 @default.
• W2130101103 cites W2078716416 @default.
• W2130101103 cites W2080317273 @default.
• W2130101103 cites W2085236252 @default.
• W2130101103 cites W2121782327 @default.
• W2130101103 cites W2131267282 @default.
• W2130101103 cites W2402522186 @default.
• W2130101103 doi "https://doi.org/10.17795/jjnpp-12504" @default.
• W2130101103 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3941888" @default.
• W2130101103 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24624211" @default.
• W2130101103 hasPublicationYear "2013" @default.
• W2130101103 type Work @default.
• W2130101103 sameAs 2130101103 @default.
• W2130101103 citedByCount "6" @default.
• W2130101103 countsByYear W21301011032014 @default.
• W2130101103 countsByYear W21301011032016 @default.
• W2130101103 countsByYear W21301011032021 @default.
• W2130101103 crossrefType "journal-article" @default.
• W2130101103 hasAuthorship W2130101103A5008097963 @default.
• W2130101103 hasAuthorship W2130101103A5031537672 @default.
• W2130101103 hasAuthorship W2130101103A5031715817 @default.
• W2130101103 hasAuthorship W2130101103A5052484286 @default.
• W2130101103 hasBestOaLocation W21301011032 @default.
• W2130101103 hasConcept C110084920 @default.
• W2130101103 hasConcept C179998833 @default.
• W2130101103 hasConcept C185592680 @default.
• W2130101103 hasConcept C192562407 @default.
• W2130101103 hasConcept C2777278459 @default.
• W2130101103 hasConcept C2779858419 @default.
• W2130101103 hasConcept C2780642067 @default.
• W2130101103 hasConcept C43617362 @default.
• W2130101103 hasConcept C49040817 @default.
• W2130101103 hasConcept C751236 @default.
• W2130101103 hasConceptScore W2130101103C110084920 @default.
• W2130101103 hasConceptScore W2130101103C179998833 @default.
• W2130101103 hasConceptScore W2130101103C185592680 @default.
• W2130101103 hasConceptScore W2130101103C192562407 @default.
• W2130101103 hasConceptScore W2130101103C2777278459 @default.
• W2130101103 hasConceptScore W2130101103C2779858419 @default.
• W2130101103 hasConceptScore W2130101103C2780642067 @default.
• W2130101103 hasConceptScore W2130101103C43617362 @default.
• W2130101103 hasConceptScore W2130101103C49040817 @default.
• W2130101103 hasConceptScore W2130101103C751236 @default.
• W2130101103 hasIssue "4" @default.
• W2130101103 hasLocation W21301011031 @default.
• W2130101103 hasLocation W21301011032 @default.
• W2130101103 hasLocation W21301011033 @default.
• W2130101103 hasLocation W21301011034 @default.
• W2130101103 hasOpenAccess W2130101103 @default.
• W2130101103 hasPrimaryLocation W21301011031 @default.
• W2130101103 hasRelatedWork W1993544909 @default.
• W2130101103 hasRelatedWork W2059451009 @default.
• W2130101103 hasRelatedWork W2079187157 @default.
• W2130101103 hasRelatedWork W2143309686 @default.
• W2130101103 hasRelatedWork W234873409 @default.
• W2130101103 hasRelatedWork W2353733990 @default.
• W2130101103 hasRelatedWork W2362334314 @default.
• W2130101103 hasRelatedWork W2363179112 @default.
• W2130101103 hasRelatedWork W2364345122 @default.
• W2130101103 hasRelatedWork W2894178975 @default.
• W2130101103 hasVolume "8" @default.
• W2130101103 isParatext "false" @default.
• W2130101103 isRetracted "false" @default.
• W2130101103 magId "2130101103" @default.
• W2130101103 workType "article" @default.