Matches in SemOpenAlex for { <https://semopenalex.org/work/W2130126775> ?p ?o ?g. }
- W2130126775 endingPage "2051" @default.
- W2130126775 startingPage "2044" @default.
- W2130126775 abstract "ABSTRACT Gibberella zeae (asexual state Fusarium graminearum ) is a major causal agent of wheat head blight and maize ear rot in North America and is responsible for contamination of grain with deoxynivalenol and related trichothecene mycotoxins. To identify additional trichothecene biosynthetic genes, cDNA libraries were prepared from fungal cultures under trichothecene-inducing conditions in culture and in planta. A gene designated LH1 that was highly expressed under these conditions exhibited only moderate (59%) similarity to known trichothecene biosynthetic cytochrome P450s. To determine the function of LH1 , gene disruptants were produced and assessed for trichothecene production. Gene disruptants no longer produced 15-acetyldeoxynivalenol, which is oxygenated at carbon 7 (C-7) and C-8, but rather accumulated calonectrin and 3-deacetylcalonectrin, which are not oxygenated at either C-7 or C-8. These results indicate that gene LH1 encodes a cytochrome P450 responsible for oxygenation at one or both of these positions. Despite the relatively low level of DNA and amino acid sequence similarity between the two genes, LH1 from G. zeae is the probable homologue of Tri1 , which encodes a cytochrome P450 required for C-8 oxygenation in F. sporotrichioides ." @default.
- W2130126775 created "2016-06-24" @default.
- W2130126775 creator A5009043761 @default.
- W2130126775 creator A5013676676 @default.
- W2130126775 creator A5026610699 @default.
- W2130126775 creator A5045843054 @default.
- W2130126775 creator A5063175531 @default.
- W2130126775 creator A5063748229 @default.
- W2130126775 creator A5070823149 @default.
- W2130126775 date "2004-04-01" @default.
- W2130126775 modified "2023-10-01" @default.
- W2130126775 title "<i>Tri1</i> in <i>Fusarium graminearum</i> Encodes a P450 Oxygenase" @default.
- W2130126775 cites W158839569 @default.
- W2130126775 cites W1990384969 @default.
- W2130126775 cites W2012617920 @default.
- W2130126775 cites W2018273981 @default.
- W2130126775 cites W2026273381 @default.
- W2130126775 cites W2042037628 @default.
- W2130126775 cites W2066695588 @default.
- W2130126775 cites W2066947345 @default.
- W2130126775 cites W2069907479 @default.
- W2130126775 cites W2078257800 @default.
- W2130126775 cites W2081888856 @default.
- W2130126775 cites W2083358836 @default.
- W2130126775 cites W2093784855 @default.
- W2130126775 cites W2098217287 @default.
- W2130126775 cites W2099830698 @default.
- W2130126775 cites W2106529938 @default.
- W2130126775 cites W2113271516 @default.
- W2130126775 cites W2115348608 @default.
- W2130126775 cites W2136597124 @default.
- W2130126775 cites W2141571911 @default.
- W2130126775 cites W2142965990 @default.
- W2130126775 cites W2145629452 @default.
- W2130126775 cites W2152460774 @default.
- W2130126775 cites W2162046720 @default.
- W2130126775 cites W2167367711 @default.
- W2130126775 cites W2333761520 @default.
- W2130126775 doi "https://doi.org/10.1128/aem.70.4.2044-2051.2004" @default.
- W2130126775 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/383062" @default.
- W2130126775 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15066795" @default.
- W2130126775 hasPublicationYear "2004" @default.
- W2130126775 type Work @default.
- W2130126775 sameAs 2130126775 @default.
- W2130126775 citedByCount "109" @default.
- W2130126775 countsByYear W21301267752012 @default.
- W2130126775 countsByYear W21301267752013 @default.
- W2130126775 countsByYear W21301267752014 @default.
- W2130126775 countsByYear W21301267752015 @default.
- W2130126775 countsByYear W21301267752016 @default.
- W2130126775 countsByYear W21301267752017 @default.
- W2130126775 countsByYear W21301267752018 @default.
- W2130126775 countsByYear W21301267752019 @default.
- W2130126775 countsByYear W21301267752020 @default.
- W2130126775 countsByYear W21301267752021 @default.
- W2130126775 countsByYear W21301267752022 @default.
- W2130126775 countsByYear W21301267752023 @default.
- W2130126775 crossrefType "journal-article" @default.
- W2130126775 hasAuthorship W2130126775A5009043761 @default.
- W2130126775 hasAuthorship W2130126775A5013676676 @default.
- W2130126775 hasAuthorship W2130126775A5026610699 @default.
- W2130126775 hasAuthorship W2130126775A5045843054 @default.
- W2130126775 hasAuthorship W2130126775A5063175531 @default.
- W2130126775 hasAuthorship W2130126775A5063748229 @default.
- W2130126775 hasAuthorship W2130126775A5070823149 @default.
- W2130126775 hasBestOaLocation W21301267752 @default.
- W2130126775 hasConcept C104317684 @default.
- W2130126775 hasConcept C181199279 @default.
- W2130126775 hasConcept C187882448 @default.
- W2130126775 hasConcept C2776889654 @default.
- W2130126775 hasConcept C2777140777 @default.
- W2130126775 hasConcept C2778867309 @default.
- W2130126775 hasConcept C2779741023 @default.
- W2130126775 hasConcept C2781266966 @default.
- W2130126775 hasConcept C526171541 @default.
- W2130126775 hasConcept C54355233 @default.
- W2130126775 hasConcept C55493867 @default.
- W2130126775 hasConcept C59822182 @default.
- W2130126775 hasConcept C84699730 @default.
- W2130126775 hasConcept C86803240 @default.
- W2130126775 hasConcept C89423630 @default.
- W2130126775 hasConceptScore W2130126775C104317684 @default.
- W2130126775 hasConceptScore W2130126775C181199279 @default.
- W2130126775 hasConceptScore W2130126775C187882448 @default.
- W2130126775 hasConceptScore W2130126775C2776889654 @default.
- W2130126775 hasConceptScore W2130126775C2777140777 @default.
- W2130126775 hasConceptScore W2130126775C2778867309 @default.
- W2130126775 hasConceptScore W2130126775C2779741023 @default.
- W2130126775 hasConceptScore W2130126775C2781266966 @default.
- W2130126775 hasConceptScore W2130126775C526171541 @default.
- W2130126775 hasConceptScore W2130126775C54355233 @default.
- W2130126775 hasConceptScore W2130126775C55493867 @default.
- W2130126775 hasConceptScore W2130126775C59822182 @default.
- W2130126775 hasConceptScore W2130126775C84699730 @default.
- W2130126775 hasConceptScore W2130126775C86803240 @default.
- W2130126775 hasConceptScore W2130126775C89423630 @default.
- W2130126775 hasIssue "4" @default.
- W2130126775 hasLocation W21301267751 @default.