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• W2130127311 abstract "Dear EditorTheriskofovarianmalignancyislowduringpregnancyandmanycasesareaKrukenbergtumor,emphasizingtheimportanceofmedicalconsultationprior to conception [1]. Any newovariangrowthshouldbeactivelymanagedinwomenwithahistoryofgastrointestinaltractcancers [2]. The following case reportis of sucha situation.A 35-year-old pregnant woman, G1P0, had a history of sigmoidcolon cancer, Dukes' stage C, 2 years ago, which was treated withlow anterior resection and postoperative adjuvant chemotherapy[5-fluorouracil/folinic acid plus oxaliplatin (FOLFOX4)], and had acompleteremission.Shereceivedoneultrasoundexaminationat17weeks' gestation without abnormal findings. Due to abdominalpain, obstetric ultrasound at 32 weeks' gestation showed an 18-cmright adnexal heterogeneous cystic mass with solid components,and the subsequent magnetic resonance imaging showed similarfindings (Fig.1). After a detailed and thorough discussion, she wasscheduled for Cesarean section (C/S) after 37 weeks' gestation.Salpingo-oophorectomy was performed after C/S. Pathologyconfirmed a 20-cm Krukenberg tumor of the right ovary withoutevidence of tumors on other sites. FOLFOX4 therapy was adminis-teredsubsequently 12timesevery2weeks.Shewasstillalive morethan 19 months after salpingo-oophorectomy.To report this case, we used the term “Krukenberg tumor, preg-nancy” (from 1956 to October 16, 2014) to search PubMed for rele-vant English-language articles, and identified only 49 publishedarticles (PubMed.gov. http://www.ncbi.nlm.nih.gov/pubmed/?term¼krukenbergþtumor%2Cþpregnancy. Accessed on 11November, 2014), suggesting that the occurrence of a Krukenbergtumor during pregnancy was extremely rare. The prognosis ofKrukenbergtumorispoor[2,3],especiallyduringpregnancy,whichis often considered to be lethal [4]. This report created a manage-ment dilemma, since the patients refused interventions that werefelt to pose a hazard to the continuation of their pregnancy,including aggressive surgery and chemotherapy. In fact, pretermbirthswereobviouslyatgreatestrisk[5].Therefore,laparotomywasdelayeduntilnearlyfull terminourcurrentcase.However,becauseofthepresenceofunexpectedrisksinpregnantwomenwithovariantumors, an earlier intervention is always suggested [1]. Some stra-tegies have been used to minimize the risks of adverse events,including the following: (1) there is no difference of treatment be-tweenpregnant and nonpregnant status; (2) elective surgerycan, ifpossible, be delayed until or after delivery; (3) if surgery is war-ranted,electronicfetal heart rateanduterinecontraction shouldbemonitored before, during, and after surgery; and (4) preconceptioncounselingandultrasoundevaluationcandecreasetheincidenceofpathological ovarian tumors during pregnancy." @default.
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• W2130127311 date "2015-04-01" @default.
• W2130127311 modified "2023-10-18" @default.
• W2130127311 title "Isolated Krukenberg tumor in pregnancy" @default.
• W2130127311 cites W2022154258 @default.
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• W2130127311 doi "https://doi.org/10.1016/j.tjog.2014.12.006" @default.
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