FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2130127752> ?p ?o ?g. }

• W2130127752 endingPage "1915" @default.
• W2130127752 startingPage "1906" @default.
• W2130127752 abstract "ABSTRACT Fungal glycosylphosphatidylinositol (GPI)-anchored proteins localize to the plasma membrane (PM), cell wall (CW), or both. To study signals that regulate PM versus CW targeting in Candida albicans , we (i) fused the N and/or C termini of the GPI CW protein Hwp1p and the GPI PM protein Ecm331p to green fluorescent protein (GFP) and (ii) expressed and localized the resulting fusions. Forty-seven amino acids from the C terminus of Hwp1p were sufficient to target GFP to the CW, and 66 amino acids from the C terminus of Ecm331p were sufficient to target GFP to the PM. Truncation and mutagenesis studies showed that G390 was the ω cleavage site in Ecm331p. Domain exchange and mutagenesis studies showed that (i) the 5 amino acids immediately N-terminal to the ω sites (the ω − 5 to ω − 1 amino acids) played key roles in targeting to the PM or CW; (ii) KK and FE residues at positions ω − 1 and ω − 2, respectively, targeted to the PM and CW; and (iii) a loss of I at position ω − 5 increased PM retention. Small fluorescent reporters can be used to study the peptide signals that regulate PM versus CW targeting of GPI proteins and may be useful for identifying proteins that interact with key targeting signals." @default.
• W2130127752 created "2016-06-24" @default.
• W2130127752 creator A5010936468 @default.
• W2130127752 creator A5036950412 @default.
• W2130127752 creator A5039562453 @default.
• W2130127752 creator A5042716043 @default.
• W2130127752 date "2008-11-01" @default.
• W2130127752 modified "2023-09-26" @default.
• W2130127752 title "C-Terminal Signals Regulate Targeting of Glycosylphosphatidylinositol-Anchored Proteins to the Cell Wall or Plasma Membrane in Candida albicans" @default.
• W2130127752 cites W1507738894 @default.
• W2130127752 cites W1515034295 @default.
• W2130127752 cites W1535701124 @default.
• W2130127752 cites W1540763009 @default.
• W2130127752 cites W1737498497 @default.
• W2130127752 cites W1893303563 @default.
• W2130127752 cites W1922008447 @default.
• W2130127752 cites W1968271109 @default.
• W2130127752 cites W1968502165 @default.
• W2130127752 cites W1996218114 @default.
• W2130127752 cites W1996677209 @default.
• W2130127752 cites W2004093637 @default.
• W2130127752 cites W2006698828 @default.
• W2130127752 cites W2007083562 @default.
• W2130127752 cites W2025805745 @default.
• W2130127752 cites W2040556195 @default.
• W2130127752 cites W2041673555 @default.
• W2130127752 cites W2043980298 @default.
• W2130127752 cites W2056605430 @default.
• W2130127752 cites W2067163578 @default.
• W2130127752 cites W2095854759 @default.
• W2130127752 cites W2099992860 @default.
• W2130127752 cites W2106860332 @default.
• W2130127752 cites W2109110922 @default.
• W2130127752 cites W2116634636 @default.
• W2130127752 cites W2116794461 @default.
• W2130127752 cites W2117903782 @default.
• W2130127752 cites W2120927037 @default.
• W2130127752 cites W2126541230 @default.
• W2130127752 cites W2129371499 @default.
• W2130127752 cites W2138126650 @default.
• W2130127752 cites W2154747365 @default.
• W2130127752 cites W2163176484 @default.
• W2130127752 cites W2163317482 @default.
• W2130127752 cites W4239539690 @default.
• W2130127752 cites W4248906151 @default.
• W2130127752 doi "https://doi.org/10.1128/ec.00148-08" @default.
• W2130127752 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2583546" @default.
• W2130127752 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18723603" @default.
• W2130127752 hasPublicationYear "2008" @default.
• W2130127752 type Work @default.
• W2130127752 sameAs 2130127752 @default.
• W2130127752 citedByCount "25" @default.
• W2130127752 countsByYear W21301277522012 @default.
• W2130127752 countsByYear W21301277522013 @default.
• W2130127752 countsByYear W21301277522014 @default.
• W2130127752 countsByYear W21301277522015 @default.
• W2130127752 countsByYear W21301277522016 @default.
• W2130127752 countsByYear W21301277522017 @default.
• W2130127752 countsByYear W21301277522018 @default.
• W2130127752 countsByYear W21301277522019 @default.
• W2130127752 crossrefType "journal-article" @default.
• W2130127752 hasAuthorship W2130127752A5010936468 @default.
• W2130127752 hasAuthorship W2130127752A5036950412 @default.
• W2130127752 hasAuthorship W2130127752A5039562453 @default.
• W2130127752 hasAuthorship W2130127752A5042716043 @default.
• W2130127752 hasBestOaLocation W21301277521 @default.
• W2130127752 hasConcept C104317684 @default.
• W2130127752 hasConcept C10858879 @default.
• W2130127752 hasConcept C14053116 @default.
• W2130127752 hasConcept C142613039 @default.
• W2130127752 hasConcept C1491633281 @default.
• W2130127752 hasConcept C151730666 @default.
• W2130127752 hasConcept C16318435 @default.
• W2130127752 hasConcept C167625842 @default.
• W2130127752 hasConcept C175156509 @default.
• W2130127752 hasConcept C2778106830 @default.
• W2130127752 hasConcept C2780917455 @default.
• W2130127752 hasConcept C43369102 @default.
• W2130127752 hasConcept C501734568 @default.
• W2130127752 hasConcept C515207424 @default.
• W2130127752 hasConcept C55493867 @default.
• W2130127752 hasConcept C57711820 @default.
• W2130127752 hasConcept C86803240 @default.
• W2130127752 hasConcept C89423630 @default.
• W2130127752 hasConcept C95444343 @default.
• W2130127752 hasConceptScore W2130127752C104317684 @default.
• W2130127752 hasConceptScore W2130127752C10858879 @default.
• W2130127752 hasConceptScore W2130127752C14053116 @default.
• W2130127752 hasConceptScore W2130127752C142613039 @default.
• W2130127752 hasConceptScore W2130127752C1491633281 @default.
• W2130127752 hasConceptScore W2130127752C151730666 @default.
• W2130127752 hasConceptScore W2130127752C16318435 @default.
• W2130127752 hasConceptScore W2130127752C167625842 @default.
• W2130127752 hasConceptScore W2130127752C175156509 @default.
• W2130127752 hasConceptScore W2130127752C2778106830 @default.
• W2130127752 hasConceptScore W2130127752C2780917455 @default.
• W2130127752 hasConceptScore W2130127752C43369102 @default.
• W2130127752 hasConceptScore W2130127752C501734568 @default.

• next