Matches in SemOpenAlex for { <https://semopenalex.org/work/W2130143669> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2130143669 endingPage "86" @default.
- W2130143669 startingPage "80" @default.
- W2130143669 abstract "Isobutyl 2-cyanoacrylate monomer placed in an osseous defect excited an intense acute inflammatory response in the early stages of repair. Fibrous encapsulation of the adhesive followed, and chronic inflammation supervened for as long as the cyanoacrylate remaine. Damage to established bone, presumable due to toxic breakdown products, occurred even at a distance from the adhesive. Osteoblastic activity was retarded where cyanoacrylate was in close proximity, recovering as fibrous encapsulation and macrophage activity provided protection. Extensive marrow damage was seen, recovery similarly following fibrous protection. Repair progressed as cyanoacrylate was removed. The findings of this investigation, together with other reports of unfavourable bone reaction to isobutyl 2-cyanoacrylate (Kerr & Smyth, 1971; Corn et al., 1972) suggest that it should not be used in bone surgery. An ideal adhesive for use in bone repair should promote rather than retard osteoblastic activity, and should resorb apace with bone regeneration. Thus isobutyl 2-cyanoacrylate does not fulfil the criteria for the ideal adhesive. Hopefully, future development of the cyanoacrylates will circumvent their current disadvantages, resulting in an adhesive acceptable for clinical use in osseous repair." @default.
- W2130143669 created "2016-06-24" @default.
- W2130143669 creator A5061797392 @default.
- W2130143669 date "1976-07-01" @default.
- W2130143669 modified "2023-09-27" @default.
- W2130143669 title "Cyanoacrylate tissue adhesive in osseous repair" @default.
- W2130143669 cites W1908463587 @default.
- W2130143669 cites W2008948680 @default.
- W2130143669 cites W2017593647 @default.
- W2130143669 cites W2022729900 @default.
- W2130143669 cites W2041156270 @default.
- W2130143669 cites W2079168467 @default.
- W2130143669 cites W2080617564 @default.
- W2130143669 cites W2084461661 @default.
- W2130143669 cites W2339371365 @default.
- W2130143669 cites W2436581594 @default.
- W2130143669 doi "https://doi.org/10.1016/0007-117x(76)90098-6" @default.
- W2130143669 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1066161" @default.
- W2130143669 hasPublicationYear "1976" @default.
- W2130143669 type Work @default.
- W2130143669 sameAs 2130143669 @default.
- W2130143669 citedByCount "18" @default.
- W2130143669 countsByYear W21301436692012 @default.
- W2130143669 countsByYear W21301436692021 @default.
- W2130143669 countsByYear W21301436692023 @default.
- W2130143669 crossrefType "journal-article" @default.
- W2130143669 hasAuthorship W2130143669A5061797392 @default.
- W2130143669 hasConcept C141071460 @default.
- W2130143669 hasConcept C159985019 @default.
- W2130143669 hasConcept C192562407 @default.
- W2130143669 hasConcept C2778171257 @default.
- W2130143669 hasConcept C2779227376 @default.
- W2130143669 hasConcept C2909647318 @default.
- W2130143669 hasConcept C68928338 @default.
- W2130143669 hasConcept C71924100 @default.
- W2130143669 hasConceptScore W2130143669C141071460 @default.
- W2130143669 hasConceptScore W2130143669C159985019 @default.
- W2130143669 hasConceptScore W2130143669C192562407 @default.
- W2130143669 hasConceptScore W2130143669C2778171257 @default.
- W2130143669 hasConceptScore W2130143669C2779227376 @default.
- W2130143669 hasConceptScore W2130143669C2909647318 @default.
- W2130143669 hasConceptScore W2130143669C68928338 @default.
- W2130143669 hasConceptScore W2130143669C71924100 @default.
- W2130143669 hasIssue "1" @default.
- W2130143669 hasLocation W21301436691 @default.
- W2130143669 hasLocation W21301436692 @default.
- W2130143669 hasOpenAccess W2130143669 @default.
- W2130143669 hasPrimaryLocation W21301436691 @default.
- W2130143669 hasRelatedWork W2031567172 @default.
- W2130143669 hasRelatedWork W2035901117 @default.
- W2130143669 hasRelatedWork W2058128786 @default.
- W2130143669 hasRelatedWork W2068401459 @default.
- W2130143669 hasRelatedWork W2075209620 @default.
- W2130143669 hasRelatedWork W2216205024 @default.
- W2130143669 hasRelatedWork W2416630317 @default.
- W2130143669 hasRelatedWork W2803577850 @default.
- W2130143669 hasRelatedWork W2927815452 @default.
- W2130143669 hasRelatedWork W359699857 @default.
- W2130143669 hasVolume "14" @default.
- W2130143669 isParatext "false" @default.
- W2130143669 isRetracted "false" @default.
- W2130143669 magId "2130143669" @default.
- W2130143669 workType "article" @default.