FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2130192989> ?p ?o ?g. }

• W2130192989 endingPage "857" @default.
• W2130192989 startingPage "857" @default.
• W2130192989 abstract "Major depresssion (MD) and coronary artery disease (CAD) frequently co-occur. The mechanisms of comorbidity are uncertain.To clarify sources of MD-CAD comorbidity.Major depression was assessed at the time of the personal interview, and CAD from hospital discharge records and death certificates.Swedish population-based twin registry.The study included 30 374 twins with a mean age of 57 years. Main Outcome Measure Modified DSM-IV diagnosis of MD or diagnosis of CAD.Lifetime association between MD and CAD was modest (odds ratio, approximately 1.3). In time-dependent Cox analyses, onset of CAD produced concurrent and ongoing hazard ratios for MD of 2.83 and 1.75. These risks increased if the diagnosis of CAD was restricted to myocardial infarction. Onset of MD increased the concurrent and ongoing hazard ratios for CAD to 2.53 and 1.17. The ongoing CAD risk was strongly associated with depressive severity and recurrence. Twin models showed that the modest comorbidity between MD and CAD in women arose primarily from shared genetic effects, although the genetic correlation was small (+0.16). In men, the source of comorbidity was moderated by age, being environmental in older members and largely genetic in younger members of the sample.Although the MD-CAD relationship across the lifespan is modest, time-dependent models reveal stronger associations. The sustained effect of CAD onset on MD risk is much stronger than vice versa. The effect of MD on CAD is largely acute, and the longer-term effects are apparently mediated via depressive recurrence. When examined separately, in men, environmental effects, which are often acute, play a large role in MD-CAD comorbidity, whereas in women, chronic effects, which are in part genetic, are more important. In men, genetic sources of MD-CAD comorbidity are more important in younger members of the sample." @default.
• W2130192989 created "2016-06-24" @default.
• W2130192989 creator A5011961838 @default.
• W2130192989 creator A5063732312 @default.
• W2130192989 creator A5066718217 @default.
• W2130192989 creator A5074112909 @default.
• W2130192989 date "2009-08-01" @default.
• W2130192989 modified "2023-10-03" @default.
• W2130192989 title "Major Depression and Coronary Artery Disease in the Swedish Twin Registry" @default.
• W2130192989 cites W1963772921 @default.
• W2130192989 cites W1972264702 @default.
• W2130192989 cites W1984959091 @default.
• W2130192989 cites W1987816992 @default.
• W2130192989 cites W1994000850 @default.
• W2130192989 cites W1999551423 @default.
• W2130192989 cites W2005518353 @default.
• W2130192989 cites W2008739372 @default.
• W2130192989 cites W2023288605 @default.
• W2130192989 cites W2027386656 @default.
• W2130192989 cites W2037806725 @default.
• W2130192989 cites W2040367735 @default.
• W2130192989 cites W2057885025 @default.
• W2130192989 cites W2062420892 @default.
• W2130192989 cites W2065084164 @default.
• W2130192989 cites W2066876424 @default.
• W2130192989 cites W2067964977 @default.
• W2130192989 cites W2084079665 @default.
• W2130192989 cites W2086124484 @default.
• W2130192989 cites W2086711080 @default.
• W2130192989 cites W2087310911 @default.
• W2130192989 cites W2091126023 @default.
• W2130192989 cites W2097740790 @default.
• W2130192989 cites W2101291212 @default.
• W2130192989 cites W2112334970 @default.
• W2130192989 cites W2112636231 @default.
• W2130192989 cites W2121762361 @default.
• W2130192989 cites W2122898463 @default.
• W2130192989 cites W2137171237 @default.
• W2130192989 cites W2137296158 @default.
• W2130192989 cites W2140660757 @default.
• W2130192989 cites W2144741700 @default.
• W2130192989 cites W2157786951 @default.
• W2130192989 cites W2158752703 @default.
• W2130192989 cites W2159011576 @default.
• W2130192989 cites W2159123213 @default.
• W2130192989 cites W2166302161 @default.
• W2130192989 cites W2995133996 @default.
• W2130192989 doi "https://doi.org/10.1001/archgenpsychiatry.2009.94" @default.
• W2130192989 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2844894" @default.
• W2130192989 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19652125" @default.
• W2130192989 hasPublicationYear "2009" @default.
• W2130192989 type Work @default.
• W2130192989 sameAs 2130192989 @default.
• W2130192989 citedByCount "130" @default.
• W2130192989 countsByYear W21301929892012 @default.
• W2130192989 countsByYear W21301929892013 @default.
• W2130192989 countsByYear W21301929892014 @default.
• W2130192989 countsByYear W21301929892015 @default.
• W2130192989 countsByYear W21301929892016 @default.
• W2130192989 countsByYear W21301929892017 @default.
• W2130192989 countsByYear W21301929892018 @default.
• W2130192989 countsByYear W21301929892019 @default.
• W2130192989 countsByYear W21301929892020 @default.
• W2130192989 countsByYear W21301929892021 @default.
• W2130192989 countsByYear W21301929892022 @default.
• W2130192989 countsByYear W21301929892023 @default.
• W2130192989 crossrefType "journal-article" @default.
• W2130192989 hasAuthorship W2130192989A5011961838 @default.
• W2130192989 hasAuthorship W2130192989A5063732312 @default.
• W2130192989 hasAuthorship W2130192989A5066718217 @default.
• W2130192989 hasAuthorship W2130192989A5074112909 @default.
• W2130192989 hasBestOaLocation W21301929891 @default.
• W2130192989 hasConcept C126322002 @default.
• W2130192989 hasConcept C127413603 @default.
• W2130192989 hasConcept C139719470 @default.
• W2130192989 hasConcept C156957248 @default.
• W2130192989 hasConcept C161890455 @default.
• W2130192989 hasConcept C162324750 @default.
• W2130192989 hasConcept C169594400 @default.
• W2130192989 hasConcept C194789388 @default.
• W2130192989 hasConcept C199639397 @default.
• W2130192989 hasConcept C207103383 @default.
• W2130192989 hasConcept C2776867660 @default.
• W2130192989 hasConcept C2778213512 @default.
• W2130192989 hasConcept C2779159551 @default.
• W2130192989 hasConcept C2908647359 @default.
• W2130192989 hasConcept C44249647 @default.
• W2130192989 hasConcept C500558357 @default.
• W2130192989 hasConcept C50382708 @default.
• W2130192989 hasConcept C54355233 @default.
• W2130192989 hasConcept C71924100 @default.
• W2130192989 hasConcept C86803240 @default.
• W2130192989 hasConcept C99454951 @default.
• W2130192989 hasConceptScore W2130192989C126322002 @default.
• W2130192989 hasConceptScore W2130192989C127413603 @default.
• W2130192989 hasConceptScore W2130192989C139719470 @default.
• W2130192989 hasConceptScore W2130192989C156957248 @default.
• W2130192989 hasConceptScore W2130192989C161890455 @default.

• next