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- W2130208052 abstract "The glucose utilization during specific delta opiate agonist-induced epileptiform phenomena, determined by the [14C]2-deoxyglucose technique (2-DG), was examined in various rat brain areas at different time intervals. The peak in EEG spiking response and the most intensive 2-DG uptake occurred 5 min after intraventricular (i.v.t.) administration of the delta opiate receptor agonist. The most pronounced 2-DG uptake at this time interval can be observed in the subiculum, including the CA1 hippocampal area, frontal cortex and central amygdala. A general decrease of glucose consumption, compared to control values, is observed after 10 min, in all regions, with exception of the subiculum. Since functional activity and 2-DG uptake are correlated, we suggest that the subiculum and/or CA1 area, are probably the brain regions most involved in the enkephalin-induced epileptic phenomena." @default.
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- W2130208052 date "1984-06-01" @default.
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- W2130208052 title "Metabolic rate in different rat brain areas during seizures induced by a specific delta opiate receptor agonist" @default.
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- W2130208052 doi "https://doi.org/10.1016/0006-8993(84)91290-3" @default.
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