FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2130265004> ?p ?o ?g. }

• W2130265004 endingPage "e0134414" @default.
• W2130265004 startingPage "e0134414" @default.
• W2130265004 abstract "Multiple sclerosis (MS) is a neurodegenerative, autoimmune disease of the central nervous system. Genome-wide association studies (GWAS) have identified over hundred polymorphisms with modest individual effects in MS susceptibility and they have confirmed the main individual effect of the Major Histocompatibility Complex. Additional risk loci with immunologically relevant genes were found significantly overrepresented. Nonetheless, it is accepted that most of the genetic architecture underlying susceptibility to the disease remains to be defined. Candidate association studies of the leukocyte immunoglobulin-like receptor LILRA3 gene in MS have been repeatedly reported with inconsistent results.In an attempt to shed some light on these controversial findings, a combined analysis was performed including the previously published datasets and three newly genotyped cohorts. Both wild-type and deleted LILRA3 alleles were discriminated in a single-tube PCR amplification and the resulting products were visualized by their different electrophoretic mobilities.Overall, this meta-analysis involved 3200 MS patients and 3069 matched healthy controls and it did not evidence significant association of the LILRA3 deletion [carriers of LILRA3 deletion: p = 0.25, OR (95% CI) = 1.07 (0.95-1.19)], even after stratification by gender and the HLA-DRB1*15:01 risk allele." @default.
• W2130265004 created "2016-06-24" @default.
• W2130265004 creator A5001625117 @default.
• W2130265004 creator A5026572220 @default.
• W2130265004 creator A5028711312 @default.
• W2130265004 creator A5029606111 @default.
• W2130265004 creator A5031012184 @default.
• W2130265004 creator A5031171090 @default.
• W2130265004 creator A5034569366 @default.
• W2130265004 creator A5035630435 @default.
• W2130265004 creator A5040203488 @default.
• W2130265004 creator A5042890325 @default.
• W2130265004 creator A5043033718 @default.
• W2130265004 creator A5057282973 @default.
• W2130265004 creator A5069196741 @default.
• W2130265004 creator A5070677379 @default.
• W2130265004 creator A5081187567 @default.
• W2130265004 creator A5081510633 @default.
• W2130265004 creator A5091751427 @default.
• W2130265004 date "2015-08-14" @default.
• W2130265004 modified "2023-10-18" @default.
• W2130265004 title "Influence of the LILRA3 Deletion on Multiple Sclerosis Risk: Original Data and Meta-Analysis" @default.
• W2130265004 cites W1496647316 @default.
• W2130265004 cites W1593677984 @default.
• W2130265004 cites W1966869437 @default.
• W2130265004 cites W1994408644 @default.
• W2130265004 cites W2011988297 @default.
• W2130265004 cites W2021191276 @default.
• W2130265004 cites W2040547343 @default.
• W2130265004 cites W2061417776 @default.
• W2130265004 cites W2067559314 @default.
• W2130265004 cites W2074849310 @default.
• W2130265004 cites W2075351740 @default.
• W2130265004 cites W2075797533 @default.
• W2130265004 cites W2081849864 @default.
• W2130265004 cites W2082062343 @default.
• W2130265004 cites W2089987448 @default.
• W2130265004 cites W2094577738 @default.
• W2130265004 cites W2096130676 @default.
• W2130265004 cites W2105490558 @default.
• W2130265004 cites W2110036277 @default.
• W2130265004 cites W2132646449 @default.
• W2130265004 cites W2135403800 @default.
• W2130265004 cites W2142155780 @default.
• W2130265004 cites W2146415150 @default.
• W2130265004 cites W2155397417 @default.
• W2130265004 cites W2164392039 @default.
• W2130265004 doi "https://doi.org/10.1371/journal.pone.0134414" @default.
• W2130265004 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4537248" @default.
• W2130265004 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26274821" @default.
• W2130265004 hasPublicationYear "2015" @default.
• W2130265004 type Work @default.
• W2130265004 sameAs 2130265004 @default.
• W2130265004 citedByCount "4" @default.
• W2130265004 countsByYear W21302650042016 @default.
• W2130265004 countsByYear W21302650042019 @default.
• W2130265004 countsByYear W21302650042020 @default.
• W2130265004 crossrefType "journal-article" @default.
• W2130265004 hasAuthorship W2130265004A5001625117 @default.
• W2130265004 hasAuthorship W2130265004A5026572220 @default.
• W2130265004 hasAuthorship W2130265004A5028711312 @default.
• W2130265004 hasAuthorship W2130265004A5029606111 @default.
• W2130265004 hasAuthorship W2130265004A5031012184 @default.
• W2130265004 hasAuthorship W2130265004A5031171090 @default.
• W2130265004 hasAuthorship W2130265004A5034569366 @default.
• W2130265004 hasAuthorship W2130265004A5035630435 @default.
• W2130265004 hasAuthorship W2130265004A5040203488 @default.
• W2130265004 hasAuthorship W2130265004A5042890325 @default.
• W2130265004 hasAuthorship W2130265004A5043033718 @default.
• W2130265004 hasAuthorship W2130265004A5057282973 @default.
• W2130265004 hasAuthorship W2130265004A5069196741 @default.
• W2130265004 hasAuthorship W2130265004A5070677379 @default.
• W2130265004 hasAuthorship W2130265004A5081187567 @default.
• W2130265004 hasAuthorship W2130265004A5081510633 @default.
• W2130265004 hasAuthorship W2130265004A5091751427 @default.
• W2130265004 hasBestOaLocation W21302650041 @default.
• W2130265004 hasConcept C104317684 @default.
• W2130265004 hasConcept C106208931 @default.
• W2130265004 hasConcept C135763542 @default.
• W2130265004 hasConcept C142724271 @default.
• W2130265004 hasConcept C153209595 @default.
• W2130265004 hasConcept C180754005 @default.
• W2130265004 hasConcept C186413461 @default.
• W2130265004 hasConcept C203014093 @default.
• W2130265004 hasConcept C207936829 @default.
• W2130265004 hasConcept C2779134260 @default.
• W2130265004 hasConcept C2780640218 @default.
• W2130265004 hasConcept C54355233 @default.
• W2130265004 hasConcept C71924100 @default.
• W2130265004 hasConcept C86803240 @default.
• W2130265004 hasConcept C95190672 @default.
• W2130265004 hasConceptScore W2130265004C104317684 @default.
• W2130265004 hasConceptScore W2130265004C106208931 @default.
• W2130265004 hasConceptScore W2130265004C135763542 @default.
• W2130265004 hasConceptScore W2130265004C142724271 @default.
• W2130265004 hasConceptScore W2130265004C153209595 @default.
• W2130265004 hasConceptScore W2130265004C180754005 @default.
• W2130265004 hasConceptScore W2130265004C186413461 @default.

• next