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- W2130283317 abstract "<h2>Abstract</h2><h3>Aims</h3> To compare the postprandial lipid responses in subjects with prediabetes (IFG and IGT), newly detected diabetes mellitus (NDDM) and normal glucose tolerance (NGT). <h3>Methods</h3> Postprandial lipid responses to a standard oral fat challenge was studied in forty-four subjects who were divided after an OGTT into NGT, pure impaired fasting glucose (PIFG), pure impaired glucose tolerance (PIGT) and NDDM. <h3>Results</h3> There was a significantly higher postprandial triglyceride (PPTg) response with a higher PPTg area under curve (<i>p</i>=0.004) and peak PPTg levels (<i>p</i>=0.003) in patients with NDDM but not with either PIFG (<i>p</i>>0.05) or PIGT (<i>p</i>>0.05) when compared with NGT. Overall, PPTg responses correlated significantly with fasting plasma glucose (<i>p</i>=0.001) and 2h plasma glucose (<i>p</i>=0.001) but not with age, sex, body mass index, waist, or insulin resistance. <h3>Conclusion</h3> Subjects with newly detected diabetes mellitus displayed postprandial hypertriglyceridemia after a standard oral fat meal challenge while no such abnormality could be demonstrated in subjects with IFG or IGT. This defect is probably related to glycemic status and insulin resistance." @default.
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- W2130283317 date "2008-06-01" @default.
- W2130283317 modified "2023-09-23" @default.
- W2130283317 title "Postprandial lipaemia in patients with impaired fasting glucose, impaired glucose tolerance and diabetes mellitus" @default.
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- W2130283317 doi "https://doi.org/10.1016/j.diabres.2008.01.016" @default.
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