FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2130286046> ?p ?o ?g. }

• W2130286046 endingPage "380" @default.
• W2130286046 startingPage "369" @default.
• W2130286046 abstract "The developmental regulation of sulfogalactosylceramide (sulfatide) synthesis, 2', 3'-cyclic nucleotide-3'-phosphohydrolase activity (CNP), and myelin basic protein (MBP) accumulation, three markers characteristic of myelinogenesis, were observed in dispersed cultures of fetal rat brain in spite of the absence of the formation of compact, multilamellar myelin. Sulfatide synthetic rate and CNP activity began to increase by 8 days in vitro (DIV) (approximately comparable to days post-natal) and reached their maxima by 20 DIV. MBP began to accumulate after 14 DEV and reached a maximum by 38 DIV. Thus, the temporal regulation of the onset of expression of these parameters, which is coordinate in vivo, has been dissociated into two sequential periods in vitro. Similarly, the regulatory mechanisms controlling the subsequent decline of the net expression of these three parameters were dissociated. Whereas, the increase in the net CNP activity ceased on schedule, the decline of sulfatide synthetic rate was delayed 20 days, and the accumulation of MBP underwent a net loss. These data suggest that there are multiple parallel but separate mechanisms of temporal regulation controlling myelinogenic gene expression, and that, among them, those factors that control MBP accumulation are more sensitive to disruption by the rigors of dissociated culture." @default.
• W2130286046 created "2016-06-24" @default.
• W2130286046 creator A5027472835 @default.
• W2130286046 creator A5033833412 @default.
• W2130286046 creator A5047073522 @default.
• W2130286046 date "1981-01-01" @default.
• W2130286046 modified "2023-09-25" @default.
• W2130286046 title "Noncoordinate regulation of myelinogenic parameters in primary cultures of dissociated fetal rat brain" @default.
• W2130286046 cites W111867139 @default.
• W2130286046 cites W1525813631 @default.
• W2130286046 cites W1604013235 @default.
• W2130286046 cites W1775749144 @default.
• W2130286046 cites W1974744225 @default.
• W2130286046 cites W1975101547 @default.
• W2130286046 cites W1987706210 @default.
• W2130286046 cites W1989488364 @default.
• W2130286046 cites W1990036302 @default.
• W2130286046 cites W1995069834 @default.
• W2130286046 cites W1998575728 @default.
• W2130286046 cites W2008609802 @default.
• W2130286046 cites W2015842861 @default.
• W2130286046 cites W2019558153 @default.
• W2130286046 cites W2020553847 @default.
• W2130286046 cites W2024139637 @default.
• W2130286046 cites W2028030425 @default.
• W2130286046 cites W2039579360 @default.
• W2130286046 cites W2040828164 @default.
• W2130286046 cites W2044838139 @default.
• W2130286046 cites W2051823174 @default.
• W2130286046 cites W2053654911 @default.
• W2130286046 cites W2053692112 @default.
• W2130286046 cites W2059994807 @default.
• W2130286046 cites W2061765618 @default.
• W2130286046 cites W2070163587 @default.
• W2130286046 cites W2071600138 @default.
• W2130286046 cites W2076306557 @default.
• W2130286046 cites W2077612016 @default.
• W2130286046 cites W2080001188 @default.
• W2130286046 cites W2084859783 @default.
• W2130286046 cites W2087355971 @default.
• W2130286046 cites W2090291124 @default.
• W2130286046 cites W2091394377 @default.
• W2130286046 cites W2092414271 @default.
• W2130286046 cites W2158459012 @default.
• W2130286046 cites W2162288195 @default.
• W2130286046 cites W2400991030 @default.
• W2130286046 cites W4234697976 @default.
• W2130286046 cites W4244132194 @default.
• W2130286046 cites W82533741 @default.
• W2130286046 cites W990858878 @default.
• W2130286046 doi "https://doi.org/10.1002/jnr.490060312" @default.
• W2130286046 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6170762" @default.
• W2130286046 hasPublicationYear "1981" @default.
• W2130286046 type Work @default.
• W2130286046 sameAs 2130286046 @default.
• W2130286046 citedByCount "65" @default.
• W2130286046 countsByYear W21302860462021 @default.
• W2130286046 crossrefType "journal-article" @default.
• W2130286046 hasAuthorship W2130286046A5027472835 @default.
• W2130286046 hasAuthorship W2130286046A5033833412 @default.
• W2130286046 hasAuthorship W2130286046A5047073522 @default.
• W2130286046 hasConcept C126322002 @default.
• W2130286046 hasConcept C134018914 @default.
• W2130286046 hasConcept C172680121 @default.
• W2130286046 hasConcept C185592680 @default.
• W2130286046 hasConcept C202751555 @default.
• W2130286046 hasConcept C207001950 @default.
• W2130286046 hasConcept C2776985911 @default.
• W2130286046 hasConcept C2778609137 @default.
• W2130286046 hasConcept C2779234561 @default.
• W2130286046 hasConcept C2780064007 @default.
• W2130286046 hasConcept C2780876595 @default.
• W2130286046 hasConcept C529278444 @default.
• W2130286046 hasConcept C54355233 @default.
• W2130286046 hasConcept C55493867 @default.
• W2130286046 hasConcept C71924100 @default.
• W2130286046 hasConcept C86803240 @default.
• W2130286046 hasConcept C95444343 @default.
• W2130286046 hasConceptScore W2130286046C126322002 @default.
• W2130286046 hasConceptScore W2130286046C134018914 @default.
• W2130286046 hasConceptScore W2130286046C172680121 @default.
• W2130286046 hasConceptScore W2130286046C185592680 @default.
• W2130286046 hasConceptScore W2130286046C202751555 @default.
• W2130286046 hasConceptScore W2130286046C207001950 @default.
• W2130286046 hasConceptScore W2130286046C2776985911 @default.
• W2130286046 hasConceptScore W2130286046C2778609137 @default.
• W2130286046 hasConceptScore W2130286046C2779234561 @default.
• W2130286046 hasConceptScore W2130286046C2780064007 @default.
• W2130286046 hasConceptScore W2130286046C2780876595 @default.
• W2130286046 hasConceptScore W2130286046C529278444 @default.
• W2130286046 hasConceptScore W2130286046C54355233 @default.
• W2130286046 hasConceptScore W2130286046C55493867 @default.
• W2130286046 hasConceptScore W2130286046C71924100 @default.
• W2130286046 hasConceptScore W2130286046C86803240 @default.
• W2130286046 hasConceptScore W2130286046C95444343 @default.
• W2130286046 hasIssue "3" @default.
• W2130286046 hasLocation W21302860461 @default.
• W2130286046 hasLocation W21302860462 @default.

• next