FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2130291707> ?p ?o ?g. }

• W2130291707 endingPage "179" @default.
• W2130291707 startingPage "78" @default.
• W2130291707 abstract "It is now over 10 years since the first avian genome [International Chicken Genome Sequencing Consortium, 2004] and the first complete avian karyotype [Masabanda et al., 2004] were both published; however, until 2014, avian cytogenetics has focused heavily on descriptive studies [e.g. Griffin et al., 2007, 2008; Skinner et al., 2009; Volker et al., 2010] with less attention to its functional relevance. Last year, however, saw 2 landmark efforts in the chromosomal studies of birds: a special issue of Chromosome Research in April and the announcement of recently completed sequences of multiple new avian genomes in Science and the BMC journals (taking the total number sequenced to over 50) in December. Studying the chromosomes of birds is, perhaps for the first time, telling us more about avian biology, function and evolution than it ever has... Conclusions. The most recent advances in avian cytogenetics have culminated in great promise not only for the study of bird karyotypes, but also for providing insight into the mechanisms of chromosome evolution in general. New avenues for investigation include gene regulation; for instance, it will become necessary to map accurately the physical location of polyadenylation and transcription start sites, important reference points that define promoters and post-transcriptional regulation. It will also become possible to sequence full-length transcripts, to allow accurate identification of alternate splicing events and their controlling elements. The ENCODE (Encyclopedia of DNA Elements) project has helped to define functional elements of the human genome, including those aforementioned as well as other chromatin signals, e.g. active chromatin, enhancers, insulators, methylation domains, etc. An effort of agENCODE is underway to include agriculturally important birds such as chicken, turkey, duck, quail, and perhaps ostrich. The study of cytogenetics will be essential here in helping to define higher-order structures in nuclear organization that show regulatory interactions within and between chromosomes. Finally, reconstruction of evolutionary events allows us to study genome organization and function not only in extant but, by extrapolation, in extinct species also. Reconstruction of avian-reptilian ancestral karyotypes will allow us to define chromosomal rearrangements in long-dead species that have captured the public imagination. Here be dragons!" @default.
• W2130291707 created "2016-06-24" @default.
• W2130291707 creator A5043379066 @default.
• W2130291707 date "2015-01-01" @default.
• W2130291707 modified "2023-10-04" @default.
• W2130291707 title "Third Report on Chicken Genes and Chromosomes 2015" @default.
• W2130291707 cites W105290573 @default.
• W2130291707 cites W10839406 @default.
• W2130291707 cites W124224637 @default.
• W2130291707 cites W14042003 @default.
• W2130291707 cites W1483519527 @default.
• W2130291707 cites W1483826831 @default.
• W2130291707 cites W1487239999 @default.
• W2130291707 cites W1492641165 @default.
• W2130291707 cites W1497909849 @default.
• W2130291707 cites W1500824227 @default.
• W2130291707 cites W1500914419 @default.
• W2130291707 cites W1510017237 @default.
• W2130291707 cites W1517914487 @default.
• W2130291707 cites W1521638283 @default.
• W2130291707 cites W1543796220 @default.
• W2130291707 cites W1566787063 @default.
• W2130291707 cites W1576019242 @default.
• W2130291707 cites W1576944993 @default.
• W2130291707 cites W1594381616 @default.
• W2130291707 cites W1603297093 @default.
• W2130291707 cites W1648352264 @default.
• W2130291707 cites W1767772592 @default.
• W2130291707 cites W1789091457 @default.
• W2130291707 cites W1834014666 @default.
• W2130291707 cites W1899959926 @default.
• W2130291707 cites W1903430549 @default.
• W2130291707 cites W1907205561 @default.
• W2130291707 cites W1921457844 @default.
• W2130291707 cites W1945579058 @default.
• W2130291707 cites W1954269708 @default.
• W2130291707 cites W1963581046 @default.
• W2130291707 cites W1963590871 @default.
• W2130291707 cites W1963818196 @default.
• W2130291707 cites W1964264035 @default.
• W2130291707 cites W1965056999 @default.
• W2130291707 cites W1965196031 @default.
• W2130291707 cites W1965283918 @default.
• W2130291707 cites W1965542501 @default.
• W2130291707 cites W1965621126 @default.
• W2130291707 cites W1965939735 @default.
• W2130291707 cites W1966175418 @default.
• W2130291707 cites W1966696179 @default.
• W2130291707 cites W1968430116 @default.
• W2130291707 cites W1968471467 @default.
• W2130291707 cites W1969109779 @default.
• W2130291707 cites W1971037720 @default.
• W2130291707 cites W1971041510 @default.
• W2130291707 cites W1971503861 @default.
• W2130291707 cites W1972344755 @default.
• W2130291707 cites W1973631950 @default.
• W2130291707 cites W1973937629 @default.
• W2130291707 cites W1973946419 @default.
• W2130291707 cites W1974450464 @default.
• W2130291707 cites W1974721505 @default.
• W2130291707 cites W1975599680 @default.
• W2130291707 cites W1976578360 @default.
• W2130291707 cites W1976859294 @default.
• W2130291707 cites W1977709885 @default.
• W2130291707 cites W1978001117 @default.
• W2130291707 cites W1978304604 @default.
• W2130291707 cites W1979997225 @default.
• W2130291707 cites W1980023815 @default.
• W2130291707 cites W1980515758 @default.
• W2130291707 cites W1980542019 @default.
• W2130291707 cites W1980659089 @default.
• W2130291707 cites W1982230962 @default.
• W2130291707 cites W1982517331 @default.
• W2130291707 cites W1982850452 @default.
• W2130291707 cites W1983016244 @default.
• W2130291707 cites W1984066495 @default.
• W2130291707 cites W1984693396 @default.
• W2130291707 cites W1984783889 @default.
• W2130291707 cites W1985163071 @default.
• W2130291707 cites W1985360406 @default.
• W2130291707 cites W1985514028 @default.
• W2130291707 cites W1985518511 @default.
• W2130291707 cites W1986211583 @default.
• W2130291707 cites W1986287091 @default.
• W2130291707 cites W1986389578 @default.
• W2130291707 cites W1986840186 @default.
• W2130291707 cites W1987600685 @default.
• W2130291707 cites W1987669043 @default.
• W2130291707 cites W1988539724 @default.
• W2130291707 cites W1988746491 @default.
• W2130291707 cites W1988763030 @default.
• W2130291707 cites W198983146 @default.
• W2130291707 cites W1991214829 @default.
• W2130291707 cites W1991321871 @default.
• W2130291707 cites W1991325956 @default.
• W2130291707 cites W1991466548 @default.
• W2130291707 cites W1991489644 @default.
• W2130291707 cites W1992380787 @default.

• next