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• W2130303232 abstract "Summary Arylamine N ‐acetyltransferases (NATs) are xenobiotic‐metabolizing enzymes involved in the detoxification of numerous aromatic chemicals. The NAT‐dependent N‐acetylation pathway has not previously been detected in plants. We demonstrate here the occurrence of the NAT‐dependent pathway in leguminous plants, due to symbiosis with Mesorhizobium loti . We cloned two NAT enzymes from M. loti and showed that these two recombinant enzymes catalysed the N‐acetylation of several known NAT substrates, including aniline‐derived pesticide residues. We also demonstrate the existence of a functional NAT‐dependent acetylation pathway in the root nodules of Lotus japonicus inoculated with M. loti . M. loti is the first non‐eukaryotic organism shown to express two catalytically active NAT isoforms. This work also provides the first evidence for acquisition of a xenobiotic detoxification pathway by a plant through symbiosis with a soil microbe." @default.
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• W2130303232 date "2006-03-03" @default.
• W2130303232 modified "2023-10-18" @default.
• W2130303232 title "Cloning, functional expression and characterization of <i>Mesorhizobium loti</i> arylamine <i>N</i>‐acetyltransferases: rhizobial symbiosis supplies leguminous plants with the xenobiotic N‐acetylation pathway" @default.
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• W2130303232 doi "https://doi.org/10.1111/j.1365-2958.2006.05114.x" @default.
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