Matches in SemOpenAlex for { <https://semopenalex.org/work/W2130303756> ?p ?o ?g. }
- W2130303756 endingPage "1409" @default.
- W2130303756 startingPage "1396" @default.
- W2130303756 abstract "Two experiments are reported in which rats with selective hippocampal lesions were tested on 2 prefrontal-dependent tasks. In Experiment 1, we compared the effects of lesions of the ventral hippocampus (vHC), dorsal hippocampus (dHC), and sham control surgery on the 5-choice reaction time task. Whereas rats with lesions of the dHC were indistinguishable from sham controls, those with vHC lesions showed increased premature responses and reduced accuracy throughout the experiment. The subsequent administration of systemic escitalopram (5 mg/kg), a selective serotonin reuptake inhibitor, reduced the number of premature responses in the vHC animals to control levels. In contrast, systemic injections of GBR 12909, a dopamine reuptake inhibitor, failed to ameliorate the impulsive deficit in the vHC group and, in addition, elevated perseverative responding in the vHC group only. In Experiment 2, we tested a separate group of rats with vHC lesions on a touchscreen visual discrimination and reversal learning task. Rats with vHC lesions acquired the visual discrimination as well as sham controls and showed normal inhibitory control of a previously reinforced response during reversal learning. These data support a role for the vHC in inhibitory control functions, especially in the inhibitory control of impulsive actions." @default.
- W2130303756 created "2016-06-24" @default.
- W2130303756 creator A5026513802 @default.
- W2130303756 creator A5033481694 @default.
- W2130303756 creator A5040576344 @default.
- W2130303756 creator A5084408913 @default.
- W2130303756 creator A5087099860 @default.
- W2130303756 date "2012-05-21" @default.
- W2130303756 modified "2023-10-13" @default.
- W2130303756 title "Inhibitory Control Deficits in Rats with Ventral Hippocampal Lesions" @default.
- W2130303756 cites W1481546376 @default.
- W2130303756 cites W1485480795 @default.
- W2130303756 cites W1545592082 @default.
- W2130303756 cites W1948130162 @default.
- W2130303756 cites W1969275478 @default.
- W2130303756 cites W1971669832 @default.
- W2130303756 cites W1972575894 @default.
- W2130303756 cites W1975355627 @default.
- W2130303756 cites W1978611927 @default.
- W2130303756 cites W1980137851 @default.
- W2130303756 cites W1980300126 @default.
- W2130303756 cites W1984214648 @default.
- W2130303756 cites W1986445373 @default.
- W2130303756 cites W1993481893 @default.
- W2130303756 cites W1995551635 @default.
- W2130303756 cites W1996762183 @default.
- W2130303756 cites W2000335045 @default.
- W2130303756 cites W2005788545 @default.
- W2130303756 cites W2014203063 @default.
- W2130303756 cites W2018008180 @default.
- W2130303756 cites W2027606489 @default.
- W2130303756 cites W2028632223 @default.
- W2130303756 cites W2028758164 @default.
- W2130303756 cites W2033080466 @default.
- W2130303756 cites W2034749662 @default.
- W2130303756 cites W2035266602 @default.
- W2130303756 cites W2036774393 @default.
- W2130303756 cites W2037522799 @default.
- W2130303756 cites W2039392173 @default.
- W2130303756 cites W2044533253 @default.
- W2130303756 cites W2044977985 @default.
- W2130303756 cites W2046713629 @default.
- W2130303756 cites W2046840120 @default.
- W2130303756 cites W2049115098 @default.
- W2130303756 cites W2051207883 @default.
- W2130303756 cites W2052032617 @default.
- W2130303756 cites W2054635078 @default.
- W2130303756 cites W2054774449 @default.
- W2130303756 cites W2057250999 @default.
- W2130303756 cites W2057731820 @default.
- W2130303756 cites W2060474172 @default.
- W2130303756 cites W2062049551 @default.
- W2130303756 cites W2063764296 @default.
- W2130303756 cites W2064268611 @default.
- W2130303756 cites W2064359602 @default.
- W2130303756 cites W2065071991 @default.
- W2130303756 cites W2066186736 @default.
- W2130303756 cites W2070102952 @default.
- W2130303756 cites W2070549053 @default.
- W2130303756 cites W2070712548 @default.
- W2130303756 cites W2072060777 @default.
- W2130303756 cites W2073158960 @default.
- W2130303756 cites W2074756660 @default.
- W2130303756 cites W2078046592 @default.
- W2130303756 cites W2079658751 @default.
- W2130303756 cites W2082791101 @default.
- W2130303756 cites W2086901501 @default.
- W2130303756 cites W2089534303 @default.
- W2130303756 cites W2094026124 @default.
- W2130303756 cites W2094047507 @default.
- W2130303756 cites W2094526136 @default.
- W2130303756 cites W2094984948 @default.
- W2130303756 cites W2098161132 @default.
- W2130303756 cites W2098736996 @default.
- W2130303756 cites W2100346695 @default.
- W2130303756 cites W2113603549 @default.
- W2130303756 cites W2116813115 @default.
- W2130303756 cites W2124407078 @default.
- W2130303756 cites W2150299732 @default.
- W2130303756 cites W2152618136 @default.
- W2130303756 cites W2156782574 @default.
- W2130303756 cites W2167179332 @default.
- W2130303756 cites W2167785873 @default.
- W2130303756 cites W2169543427 @default.
- W2130303756 cites W2257076861 @default.
- W2130303756 cites W4231652722 @default.
- W2130303756 cites W4251768519 @default.
- W2130303756 doi "https://doi.org/10.1093/cercor/bhs121" @default.
- W2130303756 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22615141" @default.
- W2130303756 hasPublicationYear "2012" @default.
- W2130303756 type Work @default.
- W2130303756 sameAs 2130303756 @default.
- W2130303756 citedByCount "78" @default.
- W2130303756 countsByYear W21303037562012 @default.
- W2130303756 countsByYear W21303037562013 @default.
- W2130303756 countsByYear W21303037562014 @default.
- W2130303756 countsByYear W21303037562015 @default.
- W2130303756 countsByYear W21303037562016 @default.