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• W2130308051 abstract "Abstract There have been some reports that folic acid inhibits phenytoin-induced gingival hyperplasia. The purpose of this double-blind study was to quantify clinically the effects of both systemic and topical administration of folic acid on phenytoin-induced gingival overgrowth in man. For a period of 6 months, one group of phenytoin patients received 2 daily topical applications of a folate solution. An additional group received 2 daily doses of systemic folate while a control group received placebo medication. Results indicate that throughout the 180-day period of the study, the topical folate significantly inhibited gingival hyperplasia to a greater extent than either systemic folate or placebo groups." @default.
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• W2130308051 date "1987-07-01" @default.
• W2130308051 modified "2023-10-16" @default.
• W2130308051 title "Effect of folate on phenytoin hyperplasia" @default.
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• W2130308051 doi "https://doi.org/10.1111/j.1600-051x.1987.tb00983.x" @default.
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