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- W2130372012 abstract "The optimal management of cancer pain requires a familiarity with a range of therapeutic options including antineoplastic therapies, analgesic pharmacotherapy, anaesthetic, neurosurgical, psychological and rehabilitation techniques. Successful pain management is characterised by the implementation of the techniques with the most favourable therapeutic index for the prevailing circumstances along with provision for repeated evaluations so that a favourable balance between pain relief and adverse effects is maintained. Currently available techniques can provide adequate relief to the vast majority of patients. For the large majority of patients, pain management involves the administration of specific analgesic approaches. Anaesthetic and neurosurgical techniques should be considered for the patient who has not obtained satisfactory pain relief. In all cases, these analgesic treatments must be skilfully integrated with the management of other symptoms. There is an universal agreement that analgesic pharmacotherapy remains the mainstay of cancer pain management. However. controversy has arisen regarding the validity and application of the ‘Three step analgesic ladder’ of the World Health Organization (WHO) which advocated three basic steps of therapy according to the severity of the presenting pain problem (Fig. 1) [I]. Despite the fact that data from a series of validation studies demonstrated" @default.
- W2130372012 created "2016-06-24" @default.
- W2130372012 creator A5062364363 @default.
- W2130372012 date "2001-10-01" @default.
- W2130372012 modified "2023-09-27" @default.
- W2130372012 title "The pharmacological management of cancer pain" @default.
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- W2130372012 doi "https://doi.org/10.1016/s0959-8049(01)80031-9" @default.
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