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- W2130381330 abstract "A successful vaccine must not only induceprotection in an artificial laboratory envi-ronment and in genetically identical labo-ratory mice, but also be able to do thesame in the real world. For new tubercu-losis (TB) vaccines this poses a majorchallenge, as exposure to related myco-bacterial species in the environment mayboth block and/or mask the immunityinduced by a new vaccine. The environ-ment may have additional, nonmycobac-terial effects on how humans respond toTB vaccines, as well as to other vaccines.These effects, which are complex to bothassess and understand, may include theresults of nutrition, other infections andexposure to immune modulating agents,such as pesticides or toxins." @default.
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- W2130381330 date "2008-08-01" @default.
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- W2130381330 title "Real vaccines in the real world: tuberculosis vaccines move south" @default.
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