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• W2130392796 abstract "<h2>Abstract</h2> Topical treatment of cutaneous lupus erythematosus usually includes potent glucocorticosteroids. However, prolonged use causes adverse side effects including skin atrophy as the foremost concern. In contrast to glucocorticosteroids, the anti-inflammatory and immunosuppressive macrolactam pimecrolimus has no atrophogenic potential. Affected areas of 11 patients with different forms of lupus erythematosus were treated with pimecrolimus 1% cream under semiocclusive conditions twice daily for 3 weeks. Skin involvement before and after therapy was assessed by means of a clinical score. In all patients, significant regression of skin lesions was observed after therapy (<i>P</i> < .001). This was an open and uncontrolled study on a limited number of cases. We suggest that pimecrolimus 1% cream could be an efficacious and safe treatment option for cutaneous lupus erythematosus." @default.
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• W2130392796 date "2004-09-01" @default.
• W2130392796 modified "2023-10-17" @default.
• W2130392796 title "Pimecrolimus 1% cream for cutaneous lupus erythematosus" @default.
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• W2130392796 doi "https://doi.org/10.1016/j.jaad.2004.01.044" @default.
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