Matches in SemOpenAlex for { <https://semopenalex.org/work/W2130408098> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2130408098 endingPage "991" @default.
- W2130408098 startingPage "984" @default.
- W2130408098 abstract "The alternation of eukaryotic life cycles between haploid and diploid phases is crucial for maintaining genetic diversity. In some organisms, the growth and development of haploid and diploid phases are nearly identical, and one might suppose that all genes required for one phase are likely to be critical for the other phase. Here, we show that targeted disruption of the chpA (cysteine- and histidine-rich-domain- [CHORD]-containing protein A) gene in haploid Aspergillus nidulans strains gives rise to chpA knockout haploids and heterozygous diploids but no chpA knockout diploids. A. nidulans chpA heterozygous diploids showed impaired conidiophore development and reduced conidiation. Deletion of chpA from diploid A. nidulans resulted in genome instability and reversion to a haploid state. Thus, our data suggest a vital role for chpA in maintenance of the diploid phase in A. nidulans. Furthermore, the human chpA homolog, Chp-1, was able to complement haploinsufficiency in A. nidulans chpA heterozygotes, suggesting that the function of CHORD-containing proteins is highly conserved in eukaryotes." @default.
- W2130408098 created "2016-06-24" @default.
- W2130408098 creator A5007353807 @default.
- W2130408098 creator A5007433152 @default.
- W2130408098 creator A5053294568 @default.
- W2130408098 creator A5067592841 @default.
- W2130408098 creator A5086285278 @default.
- W2130408098 date "2004-08-01" @default.
- W2130408098 modified "2023-10-15" @default.
- W2130408098 title "CHPA, a Cysteine- and Histidine-Rich-Domain-Containing Protein, Contributes to Maintenance of the Diploid State in <i>Aspergillus nidulans</i>" @default.
- W2130408098 cites W1484414970 @default.
- W2130408098 cites W1832077561 @default.
- W2130408098 cites W1963874309 @default.
- W2130408098 cites W1966851583 @default.
- W2130408098 cites W1967171950 @default.
- W2130408098 cites W1968592557 @default.
- W2130408098 cites W1968841865 @default.
- W2130408098 cites W1972166316 @default.
- W2130408098 cites W1985212818 @default.
- W2130408098 cites W1991585032 @default.
- W2130408098 cites W1995050753 @default.
- W2130408098 cites W2011417239 @default.
- W2130408098 cites W2023651395 @default.
- W2130408098 cites W2024655384 @default.
- W2130408098 cites W2024737416 @default.
- W2130408098 cites W2063450941 @default.
- W2130408098 cites W2066075970 @default.
- W2130408098 cites W2088357331 @default.
- W2130408098 cites W2093444601 @default.
- W2130408098 cites W2100001236 @default.
- W2130408098 cites W2150525179 @default.
- W2130408098 cites W2153870676 @default.
- W2130408098 cites W2156398812 @default.
- W2130408098 cites W2157289517 @default.
- W2130408098 cites W2160591994 @default.
- W2130408098 cites W2168705084 @default.
- W2130408098 cites W2169556026 @default.
- W2130408098 cites W2334694368 @default.
- W2130408098 cites W270861606 @default.
- W2130408098 cites W74173866 @default.
- W2130408098 doi "https://doi.org/10.1128/ec.3.4.984-991.2004" @default.
- W2130408098 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/500894" @default.
- W2130408098 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15302831" @default.
- W2130408098 hasPublicationYear "2004" @default.
- W2130408098 type Work @default.
- W2130408098 sameAs 2130408098 @default.
- W2130408098 citedByCount "8" @default.
- W2130408098 countsByYear W21304080982015 @default.
- W2130408098 countsByYear W21304080982018 @default.
- W2130408098 crossrefType "journal-article" @default.
- W2130408098 hasAuthorship W2130408098A5007353807 @default.
- W2130408098 hasAuthorship W2130408098A5007433152 @default.
- W2130408098 hasAuthorship W2130408098A5053294568 @default.
- W2130408098 hasAuthorship W2130408098A5067592841 @default.
- W2130408098 hasAuthorship W2130408098A5086285278 @default.
- W2130408098 hasBestOaLocation W21304080982 @default.
- W2130408098 hasConcept C104317684 @default.
- W2130408098 hasConcept C143065580 @default.
- W2130408098 hasConcept C143191323 @default.
- W2130408098 hasConcept C2776923806 @default.
- W2130408098 hasConcept C54355233 @default.
- W2130408098 hasConcept C86803240 @default.
- W2130408098 hasConceptScore W2130408098C104317684 @default.
- W2130408098 hasConceptScore W2130408098C143065580 @default.
- W2130408098 hasConceptScore W2130408098C143191323 @default.
- W2130408098 hasConceptScore W2130408098C2776923806 @default.
- W2130408098 hasConceptScore W2130408098C54355233 @default.
- W2130408098 hasConceptScore W2130408098C86803240 @default.
- W2130408098 hasIssue "4" @default.
- W2130408098 hasLocation W21304080981 @default.
- W2130408098 hasLocation W21304080982 @default.
- W2130408098 hasLocation W21304080983 @default.
- W2130408098 hasLocation W21304080984 @default.
- W2130408098 hasOpenAccess W2130408098 @default.
- W2130408098 hasPrimaryLocation W21304080981 @default.
- W2130408098 hasRelatedWork W1997737537 @default.
- W2130408098 hasRelatedWork W2034103052 @default.
- W2130408098 hasRelatedWork W2034625591 @default.
- W2130408098 hasRelatedWork W2066213978 @default.
- W2130408098 hasRelatedWork W2076838980 @default.
- W2130408098 hasRelatedWork W2078684637 @default.
- W2130408098 hasRelatedWork W2128665526 @default.
- W2130408098 hasRelatedWork W2144066814 @default.
- W2130408098 hasRelatedWork W2366259742 @default.
- W2130408098 hasRelatedWork W2593274445 @default.
- W2130408098 hasVolume "3" @default.
- W2130408098 isParatext "false" @default.
- W2130408098 isRetracted "false" @default.
- W2130408098 magId "2130408098" @default.
- W2130408098 workType "article" @default.