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• W2130427225 endingPage "894" @default.
• W2130427225 startingPage "889" @default.
• W2130427225 abstract "Epidemiological studies have reported the co‐occurrence of Parkinson disease (PD) and melanoma. Common genetic variants in the MC1R (melanocortin 1 receptor) gene, which determines skin and hair color, are associated with melanoma. Here we investigated whether genetic variants in MC1R modulate the risk of PD by sequencing the entire gene in 870 PD patients and 736 controls ascertained from Spain. We found that the MC1R variant p.R160W (rs1805008) is marginally associated with PD (odds ratio = 2.10, gender‐ and age‐adjusted p = 0.009, Bonferroni‐corrected p = 0.063). Our results suggest that MC1R genetic variants modulate the risk of PD disease in the Spanish population. Ann Neurol 2015;77:889–894" @default.
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• W2130427225 date "2015-03-13" @default.
• W2130427225 modified "2023-10-18" @default.
• W2130427225 title "The<i>MC1R</i>melanoma risk variant p.R160W is associated with Parkinson disease" @default.
• W2130427225 cites W1969753161 @default.
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• W2130427225 doi "https://doi.org/10.1002/ana.24373" @default.
• W2130427225 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25631192" @default.
• W2130427225 hasPublicationYear "2015" @default.
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