Matches in SemOpenAlex for { <https://semopenalex.org/work/W2130487041> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2130487041 endingPage "370" @default.
- W2130487041 startingPage "361" @default.
- W2130487041 abstract "The aerosol solvent extraction system (ASES) process was applied to prepare miconazole (MCZ) liposomes in a dry and reconstitutable form, the optimized temperature and pressure of which were 35°C and 8.0 MPa, respectively. The influence of compositions of phosphatidylcholine (PC), cholesterol (CHOL), and poloxamer 407 (POLOX) as well as the pH of hydration medium on physical and chemical stability of both dry microparticles and liposomes hydrated from them were examined following storage at 4°C and 25°C for 3 months. MCZ microparticles in dry powder were stable on storage at 4°C but degraded considerably after storage at 25°C. MCZ liposomes hydrated from dry ASES-prepared microparticles at pH 4.0 tended to aggregate, whereas those hydrated at pH 7.2 tended to reduce in size on storage, especially with the addition of CHOL. Liposomes with high MCZ content stored at 4°C degraded faster than when stored at 25°C. Addition of POLOX tended to retard the degradation of MCZ liposomes, whereas CHOL appeared to enhance the degradation on storage under both conditions. The chemical degradation of MCZ liposomes appeared to follow the acid-catalyzed hydrolysis. The MCZ liposomes prepared by the ASES process in this study were substantially internalized after being incubated with human lymphocytes." @default.
- W2130487041 created "2016-06-24" @default.
- W2130487041 creator A5017763310 @default.
- W2130487041 creator A5022315325 @default.
- W2130487041 creator A5037937718 @default.
- W2130487041 creator A5072386199 @default.
- W2130487041 date "2007-01-01" @default.
- W2130487041 modified "2023-10-16" @default.
- W2130487041 title "Physical and Chemical Stability of Miconazole Liposomes Prepared by Supercritical Aerosol Solvent Extraction System (ASES) Process" @default.
- W2130487041 cites W1978768708 @default.
- W2130487041 cites W1981334511 @default.
- W2130487041 cites W1990351411 @default.
- W2130487041 cites W2003758378 @default.
- W2130487041 cites W2016128386 @default.
- W2130487041 cites W2030424092 @default.
- W2130487041 cites W2031686813 @default.
- W2130487041 cites W2073305649 @default.
- W2130487041 cites W2077575981 @default.
- W2130487041 cites W2094978906 @default.
- W2130487041 cites W2112301293 @default.
- W2130487041 cites W2126397755 @default.
- W2130487041 cites W2157485847 @default.
- W2130487041 cites W2161555945 @default.
- W2130487041 cites W2163106863 @default.
- W2130487041 doi "https://doi.org/10.1080/10837450701369352" @default.
- W2130487041 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17763141" @default.
- W2130487041 hasPublicationYear "2007" @default.
- W2130487041 type Work @default.
- W2130487041 sameAs 2130487041 @default.
- W2130487041 citedByCount "8" @default.
- W2130487041 countsByYear W21304870412012 @default.
- W2130487041 countsByYear W21304870412013 @default.
- W2130487041 countsByYear W21304870412019 @default.
- W2130487041 countsByYear W21304870412020 @default.
- W2130487041 countsByYear W21304870412023 @default.
- W2130487041 crossrefType "journal-article" @default.
- W2130487041 hasAuthorship W2130487041A5017763310 @default.
- W2130487041 hasAuthorship W2130487041A5022315325 @default.
- W2130487041 hasAuthorship W2130487041A5037937718 @default.
- W2130487041 hasAuthorship W2130487041A5072386199 @default.
- W2130487041 hasConcept C118419359 @default.
- W2130487041 hasConcept C127413603 @default.
- W2130487041 hasConcept C178790620 @default.
- W2130487041 hasConcept C185154212 @default.
- W2130487041 hasConcept C185592680 @default.
- W2130487041 hasConcept C186399102 @default.
- W2130487041 hasConcept C2776330855 @default.
- W2130487041 hasConcept C2778918659 @default.
- W2130487041 hasConcept C2779679103 @default.
- W2130487041 hasConcept C2780471494 @default.
- W2130487041 hasConcept C41008148 @default.
- W2130487041 hasConcept C41625074 @default.
- W2130487041 hasConcept C42360764 @default.
- W2130487041 hasConcept C43617362 @default.
- W2130487041 hasConcept C4725764 @default.
- W2130487041 hasConcept C55493867 @default.
- W2130487041 hasConcept C76155785 @default.
- W2130487041 hasConcept C94412978 @default.
- W2130487041 hasConceptScore W2130487041C118419359 @default.
- W2130487041 hasConceptScore W2130487041C127413603 @default.
- W2130487041 hasConceptScore W2130487041C178790620 @default.
- W2130487041 hasConceptScore W2130487041C185154212 @default.
- W2130487041 hasConceptScore W2130487041C185592680 @default.
- W2130487041 hasConceptScore W2130487041C186399102 @default.
- W2130487041 hasConceptScore W2130487041C2776330855 @default.
- W2130487041 hasConceptScore W2130487041C2778918659 @default.
- W2130487041 hasConceptScore W2130487041C2779679103 @default.
- W2130487041 hasConceptScore W2130487041C2780471494 @default.
- W2130487041 hasConceptScore W2130487041C41008148 @default.
- W2130487041 hasConceptScore W2130487041C41625074 @default.
- W2130487041 hasConceptScore W2130487041C42360764 @default.
- W2130487041 hasConceptScore W2130487041C43617362 @default.
- W2130487041 hasConceptScore W2130487041C4725764 @default.
- W2130487041 hasConceptScore W2130487041C55493867 @default.
- W2130487041 hasConceptScore W2130487041C76155785 @default.
- W2130487041 hasConceptScore W2130487041C94412978 @default.
- W2130487041 hasIssue "4" @default.
- W2130487041 hasLocation W21304870411 @default.
- W2130487041 hasLocation W21304870412 @default.
- W2130487041 hasOpenAccess W2130487041 @default.
- W2130487041 hasPrimaryLocation W21304870411 @default.
- W2130487041 hasRelatedWork W1482825055 @default.
- W2130487041 hasRelatedWork W1999332166 @default.
- W2130487041 hasRelatedWork W2004245704 @default.
- W2130487041 hasRelatedWork W2031517488 @default.
- W2130487041 hasRelatedWork W2042675710 @default.
- W2130487041 hasRelatedWork W2064879026 @default.
- W2130487041 hasRelatedWork W2072255493 @default.
- W2130487041 hasRelatedWork W2107003887 @default.
- W2130487041 hasRelatedWork W2315139003 @default.
- W2130487041 hasRelatedWork W2375006785 @default.
- W2130487041 hasVolume "12" @default.
- W2130487041 isParatext "false" @default.
- W2130487041 isRetracted "false" @default.
- W2130487041 magId "2130487041" @default.
- W2130487041 workType "article" @default.